Heterogeneity of muscarinic receptors coupled to phosphoinositide breakdown in guinea pig brain and peripheral tissues

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1973 • 12,522 citations

Muscarinic receptor subtypes: M1 and M2 biochemical and functional characterization

1982 • 699 citations

Inositol Phospholipid Hydrolysis in Rat Cerebral Cortical Slices: I. Receptor Characterisation

1984 • 517 citations

Binding profile of a novel cardioselective muscarine receptor antagonist, AF-DX 116, to membranes of peripheral tissues and brain in the rat

1986 • 373 citations

A unique regulatory profile and regional distribution of [3H]pirenzepine binding in the rat provide evidence for distinct M1 and M2 muscarinic receptor subtypes

1983 • 298 citations

Cardioselective profile of AF-DX 116, a muscarine M2 receptor antagonist

1986 • 283 citations

Muscarinic receptor subclasses

1983 • 238 citations

Pirenzepine distinguishes between muscarinic receptor-mediated phosphoinositide breakdown and inhibition of adenylate cyclase.

1985 • 217 citations

Muscarinic agonist binding and phospholipid turnover in brain.

1983 • 185 citations

Regional Differences in the Coupling of Muscarinic Receptors to Inositol Phospholipid Hydrolysis in Guinea Pig Brain

1985 • 151 citations

On the presence in the cerebral cortex of muscarinic receptor subtypes which differ in neuronal localization, function and pharmacological properties.

1985 • 100 citations

Muscarinic Receptors and Hydrolysis of Inositol Phospholipids in Rat Cerebral Cortex and Parotid Gland

1985 • 100 citations

Pharmacological evidence for selective inhibition of gastric acid secretion by telenzepine, a new antimuscarinic drug

1985 • 93 citations

Dicyclomine, benzhexol and oxybutynine distinguish between subclasses of muscarinic binding sites

1986 • 79 citations

Pirenzepine indicates heterogeneity of muscarinic receptors linked to cerebral inositol phospholipid metabolism

1985 • 63 citations

Organ selectivity of hexahydrosiladifenidol in blocking pre-and postjunctional muscarinic receptors studied in guinea-pig ileum and rat heart

1985 • 58 citations

Differences between Binding Affinities of some Antimuscarinic Drugs in the Parotid Gland and those in the Urinary Bladder and Ileum

1983 • 52 citations

Muscarinic-receptor stimulation enhances polyphosphoinositide breakdown in guinea-pig ileum smooth muscle

1984 • 28 citations

Subclassification of muscarinic receptors in the heart, urinary bladder and sympathetic ganglia in the pithed rat

1985 • 26 citations

Carbachol stimulation of phosphatidic acid synthesis: Competitive inhibition by pirenzepine in synaptosomes from rat cerebral cortex

1985 • 26 citations