Matrix metalloproteinases (MMPs) in fresh human prostate tumour tissue and organ-cultured prostate tissue: Levels of collagenolytic and gelatinolytic MMPs are low, variable and different in fresh tissue versus organ-cultured tissue

Molecular basis of sun-induced premature skin ageing and retinoid antagonism

1996 • 1,379 citations

The Matrix Metalloproteinases and Their Inhibitors

1992 • 604 citations

Antisense RNA-Induced Reduction in Murine TIMP Levels Confers Oncogenicity on Swiss 3T3 Cells

1989 • 459 citations

Matrix metalloproteinase–1 is associated with poor prognosis in colorectal cancer

1996 • 449 citations

Inhibition of invasion and metastasis in cells transfected with an inhibitor of metalloproteinases.

1992 • 429 citations

New Ki-67-equivalent murine monoclonal antibodies (MIB 1-3) generated against bacterially expressed parts of the Ki-67 cDNA containing three 62 base pair repetitive elements encoding for the Ki-67 epitope.

1993 • 380 citations

Localization of messenger RNA for Mr 72,000 and 92,000 type IV collagenases in human skin cancers by in situ hybridization.

1992 • 331 citations

Matrix metalloproteinase–1 is associated with poor prognosis in colorectal cancer

1996 • 312 citations

Expression and localization of the matrix metalloproteinase pump‐1 (MMP‐7) in human gastric and colon carcinomas

1991 • 288 citations

Expression of collagenase-3 (matrix metalloproteinase-13) in squamous cell carcinomas of the head and neck.

1997 • 247 citations

Expression of metalloproteinase genes in human prostate cancer

1991 • 222 citations

Increased stromelysin 3 gene expression is associated with increased local invasiveness in head and neck squamous cell carcinomas.

1993 • 222 citations

Association of MMP-2 Activation Potential With Metastatic Progression in Human Breast Cancer Cell Lines Independent of MMP-2 Production

1993 • 216 citations

Role of ERK and JNK pathways in regulating cell motility and matrix metalloproteinase 9 production in growth factor-stimulated human epidermal keratinocytes

1999 • 215 citations

Expression of collagenase‐related metalloproteinase genes in human lung or head and neck tumours

1991 • 210 citations

Mechanisms Controlling the Transcription of Matrix Metalloproteinase Genes in Normal and Neoplastic Cells

1996 • 194 citations

Type IV collagenase (M(r) 72,000) expression in human prostate: benign and malignant tissue.

1993 • 181 citations

Harvey ras induction of metastatic potential depends upon oncogene activation and the type of recipient cell.

1985 • 175 citations

QUANTITATION AND IMMUNOCYTOCHEMICAL LOCALIZATION OF HUMAN SKIN COLLAGENASE IN BASAL CELL CARCINOMA

1977 • 166 citations

Matrix metalloproteinases and tissue inhibitor of metalloproteinases: a review of their role in tumorigenesis and tissue invasion.

1989 • 158 citations

Inhibition of tumor invasion of smooth muscle cell layers by recombinant human metalloproteinase inhibitor.

1991 • 135 citations

Overexpression of tissue inhibitor of metalloproteinases-2 retroviral-mediated gene transfer in vivo inhibits tumor growth and invasion.

1996 • 134 citations

Matrix metalloproteinase 9 expression in primary human prostatic adenocarcinoma and benign prostatic hyperplasia

1994 • 130 citations

Anti-invasive activity of ursolic acid correlates with the reduced expression of matrix metalloproteinase-9 (MMP-9) in HT1080 human fibrosarcoma cells.

1996 • 120 citations

Secretion of matrix metalloproteinases and their inhibitors (tissue inhibitor of metalloproteinases) by human prostate in explant cultures: reduced tissue inhibitor of metalloproteinase secretion by malignant tissues.

1993 • 119 citations

Role of Matrix Metalloproteinases in Models of Macrophage-Dependent Acute Lung Injury

1999 • 114 citations

Targeted disruption of the tissue inhibitor of metalloproteinases gene increases the invasive behavior of primitive mesenchymal cells derived from embryonic stem cells in vitro.

1992 • 109 citations

The 92-kDa gelatinase B is expressed by advanced stage melanoma cells: suppression by somatic cell hybridization with early stage melanoma cells.

1995 • 102 citations

Membrane type 1-matrix metalloproteinase (MT1-MMP) and MMP-2 immunolocalization in human prostate: change in cellular localization associated with high-grade prostatic intraepithelial neoplasia.

1999 • 91 citations

Interstitial collagenase gene expression in oral squamous cell carcinoma.

1992 • 90 citations

Collagenolytic and gelatinolytic matrix metalloproteinases and their inhibitors in basal cell carcinoma of skin: comparison with normal skin

2000 • 88 citations

In vivo suppression of immune complex-induced alveolitis by secretory leukoproteinase inhibitor and tissue inhibitor of metalloproteinases 2.

1993 • 82 citations

Hormone regulation of human prostate in organ culture.

1993 • 79 citations

Localization and quantification of mRNA for matrix metalloproteinase-2 (MMP-2) and tissue inhibitor of matrix metalloproteinase-2 (TIMP-2) in human benign and malignant prostatic tissue

2000 • 76 citations

Matrix metalloproteinases 1 and 3, tissue inhibitor of metalloproteinase-1 and the complex of metalloproteinase-1/tissue inhibitor in plasma of patients with prostate cancer

1997 • 75 citations

Increased matrix metalloproteinase-9 secretion in short-term tissue cultures of prostatic tumor cells

1996 • 51 citations

Increased expression of stromelysin‐3 in basal cell carcinomas

1994 • 46 citations

Basal Cell Carcinoma and Collagenase

1986 • 40 citations

Growth factor-induced epidermal invasion of the dermis in human skin organ culture: expression and role of matrix metalloproteinases.

1996 • 35 citations

Gelatinolytic And Caseinolytic Proteinase Activities In Human Prostatic Secretions

1993 • 34 citations

Immunohistochemical evaluation of type IV collagenase (72-kd metalloproteinase) in prostatic intraepithelial neoplasia.

1996 • 32 citations

Human skin in organ culture. Elaboration of proteolytic enzymes in the presence and absence of exogenous growth factors.

1995 • 27 citations

In vitro maintenance of human hyperplastic prostate tissue.

1971 • 26 citations

Measurement of androgen sensitivity in the human prostate in in vitro three‐dimensional histoculture

1992 • 25 citations

Characteristics of nonmalignant and malignant human prostate in organ culture.

1999 • 23 citations

In situ epithelial cell invasion in organ culture.

1993 • 19 citations

Location of 72-kd metalloproteinase (Type IV Collagenase) in untreated prostatic adenocarcinoma

1995 • 18 citations

Organ culture of benign, aging, and hyperplastic human prostate

1995 • 14 citations

Elaboration of Matrix Metalloproteinase Inhibitors by Human Skin in Organ Culture and by Skin Cells in Monolayer Culture: Relationship to Invasion

1998 • 14 citations

Role of ERK and JNK pathways in regulating cell motility and matrix metalloproteinase 9 production in growth factor-stimulated human epidermal keratinocytes

1999 • 13 citations