Usage of T‐cell receptor Vβ chain genes in fresh and cultured tumor‐infiltrating lymphocytes from human melanoma

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

A Gene Encoding an Antigen Recognized by Cytolytic T Lymphocytes on a Human Melanoma

1991 • 3,493 citations

Use of Tumor-Infiltrating Lymphocytes and Interleukin-2 in the Immunotherapy of Patients with Metastatic Melanoma

1988 • 2,196 citations

Interaction of Staphylococcus aureus toxin "superantigens" with human T cells.

1989 • 1,000 citations

Vβ-Specific Stimulation of Human T Cells by Staphylococcal Toxins

1989 • 711 citations

Spontaneous human lymphocyte-mediated cytotoxicity against tumor target cells. IX. The quantitation of natural killer cell activity

1981 • 703 citations

Evidence for the Effects of a Superantigen in Rheumatoid Arthritis

1991 • 632 citations

The T Cell Receptor

1987 • 554 citations

Tumor-specific cytolysis by lymphocytes infiltrating human melanomas.

1989 • 511 citations

Identification of specific cytolytic immune responses against autologous tumor in humans bearing malignant melanoma.

1987 • 478 citations

Immunotherapy of patients with advanced cancer using tumor-infiltrating lymphocytes and recombinant interleukin-2: a pilot study.

1988 • 432 citations

Limited heterogeneity of rearranged T-cell receptor Vα transcripts in brains of multiple sclerosis patients

1990 • 395 citations

Expansion of human tumor infiltrating lymphocytes for use in immunotherapy trials

1987 • 361 citations

Tumor localization of adoptively transferred indium-111 labeled tumor infiltrating lymphocytes in patients with metastatic melanoma.

1989 • 332 citations

Autologous tumor-specific cytotoxic T lymphocytes in the infiltrate of human metastatic melanomas. Activation by interleukin 2 and autologous tumor cells, and involvement of the T cell receptor.

1988 • 324 citations

Lysis of human melanoma cells by autologous cytolytic T cell clones. Identification of human histocompatibility leukocyte antigen A2 as a restriction element for three different antigens.

1989 • 223 citations

Evidence of Limited Variability of Antigen Receptors on Intrathyroidal T Cells in Autoimmune Thyroid Disease

1991 • 207 citations

Cytolytic T-cell clones against an autologous human melanoma: specificity study and definition of three antigens by immunoselection.

1989 • 188 citations

Natural killer cytotoxicity in the diagnosis of immune dysfunction: Criteria for a reproducible assay

1990 • 173 citations

Predominant Expression of T Cell Receptor V _α 7 in Tumor-Infiltrating Lymphocytes of Uveal Melanoma

1990 • 169 citations

T cell receptor V-segment frequencies in peripheral blood T cells correlate with human leukocyte antigen type.

1991 • 166 citations

Oligoclonality of human intestinal intraepithelial T cells.

1992 • 165 citations

Prevention and treatment of murine experimental allergic encephalomyelitis with T cell receptor V beta-specific antibodies.

1990 • 164 citations

Interleukin 4 promotes the growth of tumor-infiltrating lymphocytes cytotoxic for human autologous melanoma.

1988 • 160 citations

Specific release of granulocyte-macrophage colony-stimulating factor, tumor necrosis factor-alpha, and IFN-gamma by human tumor-infiltrating lymphocytes after autologous tumor stimulation.

1991 • 138 citations

In vitro sensitization and expansion with viable tumor cells and interleukin 2 in the generation of specific therapeutic effector cells.

1986 • 89 citations

Common Expression of Melanoma Tumor-Associated Antigens Recognized by Human Tumor Infiltrating Lymphocytes: Analysis by Human Lymphocyte Antigen Restriction

1991 • 84 citations

Antibodies specific for VB8 receptor peptide suppress experimental autoimmune encephalomyelitis.

1990 • 82 citations

Cellular Immune Response Against Autologous Human Malignant Melanoma: Are In Vitro Studies Providing a Framework for a More Effective Immunotherapy?

1990 • 81 citations

Generation of human autologous melanoma-specific cytotoxic T-cells using HLA-A2-matched allogeneic melanomas.

1990 • 80 citations

Separation of tumor-infiltrating lymphocytes from tumor cells in human solid tumors

1986 • 80 citations

Analysis of T-cell receptor alpha/beta variability in lymphocytes infiltrating a melanoma metastasis.

1992 • 52 citations

The T-cell receptor V beta gene usage in tumor-infiltrating lymphocytes and blood of patients with hepatocellular carcinoma.

1992 • 52 citations

Effects of cytokines on in vitro growth of tumor-infiltrating lymphocytes obtained from human primary and metastatic liver tumors

1991 • 43 citations

HLA restriction and T‐cell‐receptor Vβ gene expression of cytotoxic T lymphocytes reactive with human squamous‐cell carcinoma of the head and neck

1994 • 36 citations

Phase I Trial of Trimetrexate Glucuronate on a Five-Day Bolus Schedule: Clinical Pharmacology and Pharmacodynamics

1989 • 32 citations

Phenotypic characterization of murine tumor-infiltrating T lymphocytes.

1991 • 32 citations

An analysis of T‐cell‐receptor variable‐region genes in tumor‐infiltrating lymphocytes within malignant tumors

1991 • 23 citations

Induction by Interleukin-2 of Oligoclonal Expansion of Cultured Tumor-Infiltrating Lymphocytes

1990 • 21 citations

Lysis by interleukin 2-stimulated tumor-infiltrating lymphocytes of autologous and allogeneic tumor target cells

1989 • 21 citations

T-cell receptor V beta gene expression differs in tumor-infiltrating lymphocytes within primary and metastatic melanoma.

1991 • 14 citations

Two autologous melanoma-specific and MHC-restricted human T cell clones with identical intra-tumour reactivity do not share the same TCR Vα and Vβ gene families

1991 • 13 citations

Selective usage of TCR V beta in tumor-specific CTL lines isolated from ovarian tumor-associated lymphocytes.

1991 • 12 citations

Book ReviewGrand Rounds: One hundred years of internal medicine

1988 • 7 citations