Effect of a Deficiency of Thiamine on Brain Pyruvate Dehydrogenase: Enzyme Assay by Three Different Methods

α-KETO ACID DEHYDROGENASE COMPLEXES, XI. COMPARATIVE STUDIES OF REGULATORY PROPERTIES OF THE PYRUVATE DEHYDROGENASE COMPLEXES FROM KIDNEY, HEART, AND LIVER MITOCHONDRIA

1969 • 355 citations

α-Keto acid dehydrogenase complexes

1972 • 282 citations

α-Keto acid dehydrogenase complexes

1972 • 278 citations

The measurement of respiratory electron-transport-system activity in marine zooplankton

1975 • 260 citations

Lactic Dehydrogenase

1959 • 258 citations

α-Keto acid dehydrogenase complexes

1972 • 244 citations

Active and inactive forms of pyruvate dehydrogenase in rat heart and kidney: Effect of diabetes, fasting, and refeeding on pyruvate dehydrogenase interconversion

1971 • 231 citations

Correlation of enzymatic, metabolic, and behavioral deficits in thiamin deficiency and its reversal

1984 • 141 citations

Regulation of pyruvate dehydrogenase activity in Escherichia coli K12

1966 • 139 citations

An NADH-linked spectrophotometric assay for pyruvate dehydrogenase complex in crude tissue homogenates.

1981 • 139 citations

A tissue homogenizer

1960 • 131 citations

Hormonal regulation of pyruvate dehydrogenase

1971 • 127 citations

Development of mitochondrial energy metabolism in rat brain

1977 • 127 citations

Interconversion and Kinetic Properties of Pyruvate Dehydrogenase from Brain

1971 • 127 citations

Studies on the Physiological Functions of Thiamine

1961 • 123 citations

THE EFFECTS OF A THIAMINE ANTAGONIST, PYRITHIAMINE, ON LEVELS OF SELECTED METABOLIC INTERMEDIATES and ON ACTIVITIES OF THIAMINE‐DEPENDENT ENZYMES IN BRAIN and LIVER¹

1968 • 101 citations

Activities of thiamine-dependent enzymes in two experimental models of thiamine-deficiency encephalopathy 2. ?-ketoglutarate dehydrogenase

1986 • 100 citations

Activities of thiamine-dependent enzymes in two experimental models of thiamine-deficiency encephalopathy:

1985 • 96 citations

The effect of thiamine deficiency on the pyruvate decarboxylase system of the central nervous system

1965 • 91 citations

The activity of pyruvate dehydrogenase in rat brain during postnatal development

1974 • 88 citations

ANALYSIS OF THE PREFERENTIAL RELEASE OF NEWLY SYNTHESIZED ACETYLCHOLINE BY CORTICAL SLICES FROM RAT BRAIN WITH THE AID OF TWO DIFFERENT LABELLED PRECURSORS

1976 • 86 citations

THE EFFECT OF THIAMINE DEFICIENCY ON THE ACETYLCOENZYMEA AND ACETYLCHOLINE LEVELS IN THE RAT BRAIN

1973 • 70 citations

Regulation of Pyruvate-Dehydrogenase Interconversion in Rat-Liver Mitochondria as Related to the Phosphorylation State of Intramitochondrial Adenine Nucleotides

1974 • 69 citations

DECREASED METABOLISM IN VIVO OF GLUCOSE INTO AMINO ACIDS OF THE BRAIN OF THIAMINE‐DEFICIENT RATS AFTER TREATMENT WITH PYRITHIAMINE

1975 • 63 citations

THE REGULATION OF PYRUVATE DEHYDROGENASE IN BRAIN IN VIVO

1976 • 62 citations

DEVELOPMENT OF MITOCHONDRIAL PYRUVATE METABOLISM IN RAT BRAIN

1974 • 58 citations

Studies on the Pyruvate Dehydrogenase Complex in Brain with the Arylamine Acetyltransferase‐Coupled Assay

1982 • 57 citations

Brain mitochondrial metabolism in experimental thiamine deficiency

1984 • 55 citations

THE CHANGES WITH AGE IN THE PROTEIN COMPOSITION OF THE RAT BRAIN

1956 • 48 citations

Regional distribution of thiamine-dependent enzymes in normal and thiamine-deficient brain

1972 • 42 citations

A comparison of the regulation of pyruvate dehydrogenase in mitochondria from rat brain and liver

1975 • 42 citations

METABOLISM OF HIGHLY BASIC PROTEINS OF RAT BRAIN DURING POSTNATAL DEVELOPMENT

1970 • 41 citations

THE CONTROL OF PYRUVATE DEHYDROGENASE IN ISOLATED BRAIN MITOCHONDRIA

1978 • 39 citations

Thiamin Deficiency and the Pentose Phosphate Cycle in Rats: Intracerebral Mechanisms

1976 • 36 citations

PYRUVATE DECARBOXYLATION IN THIAMINE DEFICIENT BRAIN*

1964 • 34 citations

Effects of Dichloroacetate on Pyruvate Metabolism in Rat Brain in Vivo

1984 • 34 citations

Effect of Substrate Structure on Activity of Pigeon Liver Acetyl Transferase

1961 • 28 citations

Kinetic Studies of Mouse Brain Transketolase

1982 • 28 citations

METABOLISM OF <scp>d</scp>‐[U‐¹⁴C]RIBOSE IN RAT TISSUES

1971 • 28 citations

THE EFFECTS OF THIAMINE DEFICIENCY ON THE METABOLISM OF THE BRAIN–I. OXIDATION OF VARIOUS SUBSTRATES IN VITRO BY THE LIVER AND BRAIN OF NORMAL AND PYRITHIAMINE‐FED RATS*

1966 • 27 citations

Regulation of pyruvate metabolism via pyruvate carboxylase in rat brain mitochondria

1973 • 27 citations

The effect of (‐)hydroxycitrate on pyruvate metabolism in rat brain synaptosomes¹

1977 • 27 citations

Methods for the Isolation and Determination of Glutamate, Glutamine, Aspartate, and γ-Aminobutyrate in Brain

1974 • 26 citations

THE EFFECT OF DEFICIENCY OF THIAMINE ON THE METABOLISM OF [U‐¹⁴C]GLUCOSE AND [U‐¹⁴C]RIBOSE AND THE LEVELS OF AMINO ACIDS IN RAT BRAIN

1974 • 25 citations

Aktivitätsänderungen der Pyruvatdehydrogenase im Thiaminmangel

1968 • 24 citations

Effect of phenylpyruvate on pyruvate dehydrogenase activity in rat brain mitochondria

1973 • 23 citations

Brain glutamic acid decar☐ylase and open field activity in ten inbred strains of mice

1976 • 15 citations

Effects of Dichloroacetate on Pyruvate Metabolism in Rat Brain in Vivo

1984 • 6 citations

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