Deoxyribonucleic acid damage by neocarzinostatin chromophore: strand breaks generated by selective oxidation of C-5' of deoxyribose

A new method for sequencing DNA.

1977 • 7,941 citations

SUPERCOILED CIRCULAR DNA-PROTEIN COMPLEX IN Escherichia coli : PURIFICATION AND INDUCED CONVERSION TO AN OPEN CIRCULAR DNA FORM

1969 • 1,847 citations

Complete Nucleotide Sequence of the Escherichia coli Plasmid pBR322

1979 • 1,807 citations

Sulfoxide-Carbodiimide Reactions. I. A Facile Oxidation of Alcohols

1965 • 450 citations

Bleomycin-induced strand-scission of DNA. Mechanism of deoxyribose cleavage.

1981 • 415 citations

Enzymatic Breakage and Joining of Deoxyribonucleic Acid

1968 • 344 citations

A Deoxyribonucleic Acid Phosphatase-Exonuclease from Escherichia coli

1964 • 332 citations

Sequence specific cleavage of DNA by the antitumor antibiotics neocarzinostatin and bleomycin.

1978 • 299 citations

A new endonuclease from Escherichia coli acting at apurinic sites in DNA.

1977 • 225 citations

Origin of malondialdehyde from DNA degraded by Fe(II) x bleomycin.

1980 • 172 citations

Neocarzinostatin: Spectral characterization and separation of a non-protein chromophore

1979 • 163 citations

Roles of chromophore and apo-protein in neocarzinostatin action.

1980 • 110 citations

Strand-scission of DNA by neocarzinostatin, auromomycin, and bleomycin: studies on base release and nucleotide sequence specificity

1981 • 109 citations

[6] Specific labeling of 3′ termini with T4 DNA polymerase

1980 • 102 citations

Neocarzinostatin chromophore binds to deoxyribonucleic acid by intercalation

1981 • 92 citations

Binding of the nonprotein chromophore of neocarzinostatin to deoxyribonucleic acid

1980 • 92 citations

Characterization of DNA strand breakage in vitro by the antitumor protein neocarzinostatin

1977 • 88 citations

Activation and inactivation of neocarzinostatin-induced cleavage of DNA

1978 • 71 citations

Nucleotide specificity in DNA scission by neocarzinostatin.

1978 • 70 citations

Stabilization of neocarzinostatin nonprotein chromophore activity by interaction with apoprotein and with HeLa cells

1980 • 70 citations

Identification of thymidine-5′-aldehyde at DNA strand breaks induced by neocarzinostatin chromophore

1982 • 60 citations

Gaps in DNA induced by neocarzinostatin bear 3'- and 5'-phosphoryl termini

1978 • 57 citations

Deoxyribonucleic acid sugar damage in the action of neocarzinostatin

1980 • 51 citations

release of thymine from DNA by neocarzinostatin

1976 • 40 citations

Covalent adducts of DNA and the nonprotein chromophore of neocarzinostatin contain a modified deoxyribose.

1982 • 39 citations

Neocarzinostatin chromophore: Presence of a cyclic carbonate subunit and its modification in the structure of other biologically active forms

1981 • 31 citations

Apurinic/apyrimidinic endonuclease sensitive sites as intermediates in the in vitro degradation of deoxyribonucleic acid by neocarzinostatin

1980 • 30 citations

Effect of neocarzinostatin-induced strand scission on the template activity of DNA for DNA polymerase I

1977 • 24 citations

Neocarzinostatin chromophore-DNA adducts: evidence for a covalent linkage to the oxidized C-5′ of deoxyribose

1982 • 15 citations

Reconstitution of neocarzinostatin (NCS).

1982 • 9 citations