C-terminal Residues 621–635 of Protein S Are Essential for Binding to Factor Va

General method for the rapid solid-phase synthesis of large numbers of peptides: specificity of antigen-antibody interaction at the level of individual amino acids.

1985 • 1,650 citations

Deficiency of protein C in congenital thrombotic disease.

1981 • 1,260 citations

Familial protein S deficiency is associated with recurrent thrombosis.

1984 • 614 citations

Plasma protein S deficiency in familial thrombotic disease

1984 • 516 citations

Regulation of activated protein C by a new protein. A possible function for bovine protein S.

1980 • 460 citations

Homozygous Protein C Deficiency Manifested by Massive Venous Thrombosis in the Newborn

1984 • 444 citations

Regulation of activated protein C by protein S. The role of phospholipid in factor Va inactivation.

1981 • 397 citations

High molecular weight complex in human plasma between vitamin K-dependent protein S and complement component C4b-binding protein.

1981 • 373 citations

INHERITED PROTEIN C DEFICIENCY AND COUMARIN-RESPONSIVE CHRONIC RELAPSING PURPURA FULMINANS IN A NEWBORN INFANT

1983 • 346 citations

Factor V and protein S as synergistic cofactors to activated protein C in degradation of factor VIIIa.

1994 • 307 citations

Protein C Deficiency in a Dutch Family with Thrombotic Disease

1982 • 287 citations

Characterization of protein S, a .gamma.-carboxyglutamic acid containing protein from bovine and human plasma

1979 • 259 citations

Binding of protein S to factor Va associated with inhibition of prothrombinase that is independent of activated protein C.

1993 • 220 citations

Isolation and sequence of the cDNA for human protein S, a regulator of blood coagulation.

1986 • 204 citations

SCHIZOPHRENIA-MELANOSIS

1965 • 203 citations

Protein S binds to and inhibits factor Xa.

1994 • 167 citations

Kinetics of inactivation of membrane-bound factor Va by activated protein C. Protein S modulates factor Xa protection.

1988 • 158 citations

Human protein S inhibits prothrombinase complex activity on endothelial cells and platelets via direct interactions with factors Va and Xa.

1994 • 157 citations

Hereditary protein S deficiency and venous thrombo-embolism. A study in three Dutch families.

1985 • 108 citations

Immunoaffinity isolation of membrane antigens with biotinylated monoclonal antibodies and immobilized streptavidin matrices

1984 • 98 citations

Prothrombinase complex assembly on the platelet surface is mediated through the 74,000-dalton component of factor Va.

1983 • 94 citations

Identification of the binding site for activated protein C on the light chain of factors V and VIII.

1990 • 88 citations

The Interaction of Protein S with the Phospholipid Surface Is Essential for the Activated Protein C-independent Activity of Protein S

1996 • 76 citations

Hereditary Protein S Deficiency and Venous Thrombo-Embolism

1985 • 69 citations

Binding sites for blood coagulation factor Xa and protein S involving residues 493–506 in factor Va

1996 • 59 citations

Molecular recognition sites on factor Xa which participate in the prothrombinase complex.

1992 • 57 citations

Identification of residues 413-433 of plasma protein S as essential for binding to C4b-binding protein

1993 • 52 citations

Identification of a sequence of human activated protein C (residues 390-404) essential for its anticoagulant activity.

1991 • 50 citations

The SHBG‐like region of protein S is crucial for factor V‐dependent APC‐cofactor function

1998 • 48 citations

Epitope mapping of functional domains of human factor Va with human and murine monoclonal antibodies. Evidence for the interaction of heavy chain with factor Xa and calcium

1987 • 47 citations

Interaction of Calcium with Native and Decarboxylated Human Factor X.

1997 • 45 citations

Contribution of the Heavy and Light Chains of Factor Va to the Interaction with Factor Xa

1994 • 44 citations

Binding Site for C4b-Binding Protein in Vitamin K-Dependent Protein S Fully Contained in Carboxy-Terminal Laminin-G-type Repeats. A Study Using Recombinant Factor IX-Protein S Chimeras and Surface Plasmon Resonance

1997 • 42 citations

Binding Site for Blood Coagulation Factor Xa Involving Residues 311–325 in Factor Va

1998 • 42 citations

A Region of Vitamin K-dependent Protein S That Binds to C4b Binding Protein (C4BP) Identified Using Bacteriophage Peptide Display Libraries

1997 • 34 citations

A novel exosite in the light chain of human activated protein C essential for interaction with blood coagulation factor Va

1993 • 32 citations

Increased prothrombin activation in protein S-deficient plasma under flow conditions on endothelial cell matrix: an independent anticoagulant function of protein S in plasma

1995 • 30 citations

A Plasma Coagulation Assay for an Activated Protein C-independent Anticoagulant Activity of Protein S

1998 • 29 citations

Studies of the Interaction between Human Protein S and Human C4b-Binding Protein Using Deletion Variants of Recombinant Human Protein S

1994 • 29 citations

Interactions and inhibition of blood coagulation factor Va involving residues 311–325 of activated protein C

1993 • 24 citations

Involvement of Amino Acid Residues 423–429 of Human Protein S in Binding to C4b-Binding Protein

1998 • 22 citations

Screening of protein S deficiency using a functional assay in patients with venous and arterial thrombosis

1990 • 21 citations

[Hemostasis parameters in 55 patients with venous and/or arterial thromboembolisms].

1989 • 20 citations

Regulation of activated protein C by factor Xa

1991 • 10 citations