A New Class of HIV-1 Tat Antagonist Acting through Tat−TAR Inhibition

Investigation of exchange processes by two-dimensional NMR spectroscopy

1979 • 4,720 citations

Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

1986 • 2,918 citations

Natural abundance nitrogen-15 NMR by enhanced heteronuclear spectroscopy

1980 • 2,519 citations

Clean TOCSY for proton spin system identification in macromolecules

1988 • 1,128 citations

Conformation of the TAR RNA-Arginine Complex by NMR Spectroscopy

1992 • 594 citations

HIV-1 Tat protein promotes formation of more-processive elongation complexes.

1991 • 295 citations

High Affinity Binding of TAR RNA by the Human Immunodeficiency Virus Type-1 tat Protein Requires Base-pairs in the RNA Stem and Amino Acid Residues Flanking the Basic Region

1993 • 281 citations

NMR of macromolecules : a practical approach

1993 • 227 citations

Implications and concepts of polyamine‐nucleic acid interactions

1991 • 179 citations

Synthesis and mode(s) of action of a new series of imide derivatives of 3-nitro-1,8 naphthalic acid

1980 • 129 citations

The Regulation of Human Immunodeficiency Virus Type‐1 Gene Expression

1996 • 123 citations

Hydrogen-bonding Contacts in the Major Groove are required for Human Immunodeficiency Virus Type-1 tat Protein Recognition of TAR RNA

1993 • 109 citations

Treatment of human immunodeficiency virus type 1 (HIV-1)-infected cells with combinations of HIV-1-specific inhibitors results in a different resistance pattern than does treatment with single-drug therapy

1993 • 107 citations

Visualization of drug-nucleic acid interactions at atomic resolution

1979 • 102 citations

Location of spermine and other polyamines on DNA as revealed by photoaffinity cleavage with poly(amino)benzenediazonium salts

1991 • 97 citations

Critical chemical features in trans-acting-responsive RNA are required for interaction with human immunodeficiency virus type 1 Tat protein

1991 • 79 citations

Detailed mutational analysis of TAR RNA: critical spacing between the bulge and loop recognition domains

1991 • 76 citations

The Human Immunodeficiency Virus Long Terminal Repeat Includes a Specialised Initiator Element which is Required for Tat-responsive Transcription

1995 • 65 citations

The cellular factor TRP-185 regulates RNA polymerase II binding to HIV-1 TAR RNA.

1995 • 45 citations

The treatment of antiretroviral-naive subjects with the 3TC/zidovudine combination: a review of North American (NUCA 3001) and European (NUCB 3001) trials

1996 • 30 citations