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Strengths and limitations of meta-analysis: Larger studies may be more reliable

Data up to Jan 2025

Published1997
Citations229
References47

Total Citations Per Year

Abstract

References (47)

Meta-analysis in clinical trials

1986 • 36,193 citations

Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. Analysis and examples

1977 • 8,468 citations

COLLABORATIVE OVERVIEW OF RANDOMIZED TRIALS OF ANTIPLATELET THERAPY .1. PREVENTION OF DEATH, MYOCARDIAL-INFARCTION, AND STROKE BY PROLONGED ANTIPLATELET THERAPY IN VARIOUS CATEGORIES OF PATIENTS

1994 • 3,408 citations

Beta blockade during and after myocardial infarction: An overview of the randomized trials

1985 • 3,248 citations

Publication bias in clinical research

1991 • 3,034 citations

Collaborative overview of randomised trials of antiplatelet therapy Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients

1994 • 2,993 citations

Clinical Trials: A Practical Approach.

1984 • 2,966 citations

EFFECTIVENESS OF INTRAVENOUS THROMBOLYTIC TREATMENT IN ACUTE MYOCARDIAL INFARCTION

1986 • 2,315 citations

Design and analysis of randomized clinical trials requiring prolonged observation of each patient. I. Introduction and design

1976 • 2,290 citations

Indications for fibrinolytic therapy in suspected acute myocardial infarction : collaborative overview of early mortality and major morbidity results from all randomised trials of more than 1000 patients

1994 • 2,250 citations

Indications for fibrinolytic therapy in suspected acute myocardial infarction: collaborative overview of early mortality and major morbidity results from all randomised trials of more than 1000 patients

1994 • 2,186 citations

Effect of coronary artery bypass graft surgery on survival: overview of 10-year results from randomised trials by the Coronary Artery Bypass Graft Surgery Trialists Collaboration

1994 • 2,115 citations

ISIS-4: A randomised factorial trial assessing early oral captopril, oral mononitrate, and intravenous magnesium sulphate in 58 050 patients with suspected acute myocardial infarction

1995 • 1,786 citations

Assessing the quality of randomized controlled trials: An annotated bibliography of scales and checklists

1995 • 1,323 citations

TRIAL OF TISSUE PLASMINOGEN ACTIVATOR FOR MORTALITY REDUCTION IN ACUTE MYOCARDIAL INFARCTION

1988 • 1,161 citations

ISIS-4 - A randomised factorial assessing early oral captopril, oral mononitrate, and intravenous magnesium sulphate in 58.050 patient with suspected acute myocardial-infarction.

1995 • 1,124 citations

Methods for combining randomized clinical trials: Strengths and limitations

1987 • 998 citations

Publication bias and clinical trials

1987 • 715 citations

Why do we need some large, simple randomized trials?

1984 • 692 citations

Intravenous and intracoronary fibrinolytic therapy in acute myocardial infarction: Overview of results on mortality, reinfarction and side-effects from 33 randomized controlled trials

1985 • 578 citations

Completeness of reporting of trials published in languages other than English: implications for conduct and reporting of systematic reviews

1996 • 543 citations

Intravenous magnesium sulphate in suspected acute myocardial infarction: results of the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2)

1992 • 540 citations

Invited Commentary: A Critical Look at Some Popular Meta-Analytic Methods

1994 • 516 citations

A comparison of statistical methods for combining event rates from clinical trials

1989 • 426 citations

Why do we need systematic overviews of randomized trials? (Transcript of an oral presentation, modified by the editors)

1987 • 404 citations

Effects of intravenous magnesium in suspected acute myocardial infarction: overview of randomised trials.

1991 • 336 citations

Approaches to sample size estimation in the design of clinical trials—a review

1984 • 251 citations

Meta‐analysis of clinical trials as a scientific discipline. I: Control of bias and comparison with large co‐operative trials

1987 • 245 citations

Confronting publication bias: A cohort design for meta‐analysis

1987 • 220 citations

Effect of Intravenous Streptokinase on Acute Myocardial Infarction

1982 • 206 citations

Avoidance of large biases and large random errors in the assessment of moderate treatment effects: The need for systematic overviews

1987 • 180 citations

Problems induced by meta‐analyses

1991 • 151 citations

Clinical trial methodology

2015 • 145 citations

Efficacy of intravenous magnesium in acute myocardial infarction in reducing arrhythmias and mortality. Meta-analysis of magnesium in acute myocardial infarction.

1992 • 138 citations

Intravenous infusion of magnesium sulphate after acute myocardial infarction: effects on arrhythmias and mortality

1986 • 131 citations

Discordance between Meta-analyses and Large-Scale Randomized, Controlled Trials: Examples from the Management of Acute Myocardial Infarction

1995 • 129 citations

Inter‐study differences: How should they influence the interpretation and analysis of results?

1987 • 111 citations

Clinical trial methodology

1978 • 106 citations

Protocol for a prospective collaborative overview of all current and planned randomized trials of cholesterol treatment regimens

1995 • 96 citations

Alteration of cellular ribonucleases associated with murine oncogenic virus infection.

1978 • 94 citations

Estimation issues in clinical trials and overviews

1990 • 90 citations

Keynote addresses. Meta‐analysis: Reconciling the results of independent studies

1995 • 86 citations

Mega-trials and management of acute myocardial infarction

1995 • 71 citations

Toward prospective registration of clinical trials

1988 • 59 citations

Obtaining medically meaningful answers from an overview of randomized clinical trials

1987 • 55 citations

Meta-analysis and evidence

1989 • 54 citations

Lessons from overviews of cardiovascular trials

1987 • 52 citations

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