Tyrosine Hydroxylase Activation and Inactivation by Protein Phosphorylation Conditions

A Method for Determining the Sedimentation Behavior of Enzymes: Application to Protein Mixtures

1961 • 5,561 citations

A study of the factors affecting the aluminum oxide-trihydroxyindole procedure for the analysis of catecholamines.

1962 • 2,236 citations

ELUCIDATION OF THE RATE-LIMITING STEP IN NOREPINEPHRINE BIOSYNTHESIS IN THE PERFUSED GUINEA-PIG HEART.

1965 • 1,002 citations

[43] Preparation of homogeneous cyclic AMP-dependent protein kinase(s) and its subunits from rabbit skeletal muscle

1974 • 496 citations

Assay of tyrosine hydroxylase by coupled decarboxylation of dopa formed from 1-14C-l-tyrosine

1971 • 461 citations

Tritosol: A new scintillation cocktail based on Triton X-100

1975 • 389 citations

Inhibitors of purified beef adrenal tyrosine hydroxylase

1965 • 327 citations

Increased synthesis of norepinephrine and epinephrine in the intact rat during exercise and exposure to cold.

1966 • 326 citations

Tyrosine hydroxylase in rat brain—cofactor requirements, regional and subcellular distribution

1972 • 308 citations

Direct phosphorylation of brain tyrosine hydroxylase by cyclic AMP-dependent protein kinase: mechanism of enzyme activation.

1978 • 286 citations

ATP, cyclic AMP, and magnesium increase the affinity of rat striatal tyrosine hydroxylase for its cofactor.

1975 • 184 citations

Evidence for involvement of protein kinase in the activation by adenosine 3':5'-monophosphate of brain tyrosine 3-monooxygenase.

1975 • 179 citations

THE MOLECULAR WEIGHT OF CRYSTALLINE CATALASE

1938 • 169 citations

A Kinetic Study of Bovine Adrenal Tyrosine Hydroxylase

1966 • 167 citations

The regulation of norepinephrine synthesis in sympathetic nerves: effect of nerve stimulation, cocaine, and catecholamine-releasing agents.

1966 • 164 citations

Effects of Neuroleptics on Striatal Tyrosine Hydroxylase: Changes in Affinity for the Pteridine Cofactor

1974 • 141 citations

Tyrosine hydroxylase. Activation by protein phosphorylation and end product inhibition.

1978 • 130 citations

Haloperidol: Effect of Long-Term Treatment on Rat Striatal Dopamine Synthesis and Turnover

1977 • 123 citations

Properties of mitochondrial malate dehydrogenases

1962 • 117 citations

Stimulation of tyrosine hydroxylase activity by cyclic amp in synaptosomes and in soluble striatal enzyme preparations

1976 • 110 citations

Acceleration of norepinephrine synthesis in the rat submaxillary gland during sympathetic nerve stimulation

1967 • 107 citations

Evidence for the lack of direct phosphorylation of bovine caudate tyrosine hydroxylase following activation by exposure to enzymatic phosphorylating conditions

1975 • 93 citations

Regulation of bovine adrenal tyrosine 3-monooxygenase by phosphorylation-dephosphorylation reaction, catalyzed by adenosine 3‘:5‘-monophosphate-dependent protein kinase and phosphoprotein phosphatase.

1979 • 83 citations

Increased synthesis of norepinephrine in the rat heart on electrical stimulation of the stellate ganglia.

1966 • 80 citations

[48] Purification and characterization of an inhibitor protein of cyclic AMP-dependent protein kinases

1974 • 70 citations

Acceleration of noradrenaline turnover in the mouse heart by cold exposure

1965 • 69 citations

A simple radioisotope assay for phenylalanine hydroxylase cofactor

1967 • 64 citations

Isolation and characterization of a tyrosine hydroxylase cofactor from bovine adrenal medulla.

1971 • 62 citations

Changes of kinetic constant of striatal tyrosine hydroxylase elicited by neuroleptics that impair the function of dopamine receptors

1974 • 55 citations

Bovine brain adenosine 3',5'-monophosphate dependent protein kinase. Mechanism of regulatory subunit inhibition of the catalytic subunit

1975 • 55 citations

Factors influencing the rate of norepinephrine biosynthesis in nerve tissue.

1967 • 55 citations

[109] Phenylalanine hydroxylase

1962 • 49 citations

Adenosine cyclic 3',5'-monophosphate dependent protein kinase: active site directed inhibition by Cibacron Blue F3GA

1980 • 49 citations

Biosynthesis of the sympathetic neurotransmitter, norepinephrine.

1966 • 47 citations

The effects of phosphatidylinositol on tyrosine hydroxylase. Stimulation and inactivation.

1979 • 44 citations

Über den einfluss von harnstoff auf die molekulare struktur von lactat-dehydrogenase aus dem schweineherz

1962 • 38 citations

The effect of ethylene glycol bis(beta-aminoethyl ether-N,N'-tetraacetic acid and calcium on tyrosine hydroxylase activity.

1977 • 16 citations

Activation by cyclic AMP of soluble tyrosine hydroxylase in bovine adrenal medulla

1977 • 15 citations

Radiometric assay of tyrosine hydroxylase and tryptophan hydroxylase by Kalignost extraction procedures

1977 • 9 citations