Site-directed mutagenesis of human ferrochelatase: Identification of histidine-263 as a binding site for metal ions

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes.

1985 • 2,450 citations

Zinc Finger-DNA Recognition: Crystal Structure of a Zif268-DNA Complex at 2.1 Å

1991 • 2,034 citations

Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain

1987 • 1,640 citations

Transition Metals in Control of Gene Expression

1993 • 629 citations

Atomic Structure of the DNA Repair [4Fe-4S] Enzyme Endonuclease III

1992 • 289 citations

Studies on ferrochelatase. 1. Assay and properties of ferrochelatase from a pig-liver mitochondrial extract

1963 • 289 citations

The structural organization of haem synthesis in rat liver mitochondria

1969 • 231 citations

Human ferrochelatase is an iron-sulfur protein

1994 • 208 citations

Bovine ferrochelatase. Kinetic analysis of inhibition by N-methylprotoporphyrin, manganese, and heme.

1983 • 159 citations

Molecular cloning and sequence analysis of cDNA encoding human ferrochelatase

1990 • 138 citations

Rat liver ferrochelatase. Purification, properties, and stimulation by fatty acids.

1981 • 129 citations

Cloning and characterization of the Bacillus subtilis hemEHY gene cluster, which encodes protoheme IX biosynthetic enzymes

1992 • 125 citations

Human Erythropoietic Protoporphyria: Two point mutations in the ferrochelatase gene

1991 • 116 citations

Isolation and characterization of visible light-sensitive mutants of Escherichia coli K12

1991 • 102 citations

The ferrochelatase from Saccharomyces cerevisiae. Sequence, disruption, and expression of its structural gene HEM15.

1990 • 96 citations

Uroporphyrinogen Decarboxylase Structural Mutant (Gly281→Glu) in a Case of Porphyria

1986 • 95 citations

A molecular defect in human protoporphyria.

1992 • 88 citations

Characterization of a Bradyrhizobium japonicum ferrochelatase mutant and isolation of the hemH gene

1992 • 87 citations

Molecular cloning, sequencing, and expression of mouse ferrochelatase.

1990 • 87 citations

Purification and Substrate Specificity of Bovine Liver‐Ferrochelatase

1982 • 78 citations

Ferrochelatase Structural Mutant (Fechm1Pas) in the House Mouse

1993 • 68 citations

Mammalian ferrochelatase. Expression and characterization of normal and two human protoporphyric ferrochelatases.

1994 • 68 citations

Cloning and expression of the defective genes from a patient with delta-aminolevulinate dehydratase porphyria.

1992 • 62 citations

Effect of sulfhydryl group modification on the activity of bovine ferrochelatase.

1984 • 54 citations

Molecular defect in human erythropoietic protoporphyria with fatal liver failure

1993 • 51 citations

Does ferredoxin I (Azotobacter) represent a novel class of DNA‐binding proteins that regulate gene expression in response to cellular iron(II)?

1991 • 49 citations

Ferrochelatase activity in human lymphocytes, as quantified by a new high-performance liquid-chromatographic method.

1988 • 38 citations

Mammalian ferrochelatase. Overexpression in Escherichia coli as a soluble protein, purification and characterization.

1994 • 36 citations

Ferrochelatase activity in human lymphocytes, as quantified by a new high-performance liquid-chromatographic method.

1988 • 35 citations

A novel mutation in erythropoietic protoporphyria: an aberrant ferrochelatase mRNA caused by exon skipping during RNA splicing

1993 • 35 citations

Structure-function studies of yeast ferrochelatase. Identification and functional analysis of amino acid substitutions that increase Vmax and the KM for both substrates.

1993 • 32 citations

The role of arginyl residues in porphyrin binding to ferrochelatase.

1986 • 26 citations

Characterization of ferrochelatase in kidney and erythroleukemia cells

1990 • 24 citations

Overexpression in Escherichia coli, and one-step purification of the human recombinant ferrochelatase

1994 • 18 citations