Effect of Aerosolized Uridine-5 ′ -Triphosphate on Airway Clearance with Cough in Patients with Primary Ciliary Dyskinesia

A Human Syndrome Caused by Immotile Cilia

1976 • 1,235 citations

Mucociliary clearance in the airways.

1996 • 701 citations

The Immotile-Cilia Syndrome

1977 • 635 citations

Activation by Extracellular Nucleotides of Chloride Secretion in the Airway Epithelia of Patients with Cystic Fibrosis

1991 • 495 citations

Human airway ion transport. Part one.

1994 • 446 citations

Coordinated clearance of periciliary liquid and mucus from airway surfaces.

1998 • 374 citations

A Pilot Study of Aerosolized Amiloride for the Treatment of Lung Disease in Cystic Fibrosis

1990 • 348 citations

Mechanics of Breathing

2002 • 321 citations

Clearance of mucus by simulated cough

1985 • 224 citations

Altered Fluid Transport Across Airway Epithelium in Cystic Fibrosis

1993 • 222 citations

Human airway ion transport. Part two.

1994 • 188 citations

Effect of uridine 5'-triphosphate plus amiloride on mucociliary clearance in adult cystic fibrosis.

1996 • 169 citations

Evidence that UTP and ATP regulate phospholipase C through a common extracellular 5'-nucleotide receptor in human airway epithelial cells.

1991 • 158 citations

Rheology of Cystic Fibrosis Sputum after in vitro Treatment with Hypertonic Saline Alone and in Combination with Recombinant Human Deoxyribonuclease I

1997 • 157 citations

Chloride secretory response to extracellular ATP in human normal and cystic fibrosis nasal epithelia

1992 • 134 citations

Control of the beat cycle of respiratory tract cilia by Ca2+ and cAMP

1992 • 127 citations

Nucleotide Regulation of Goblet Cells in Human Airway Epithelial Explants: Normal Exocytosis in Cystic Fibrosis

1993 • 127 citations

Acute safety and effects on mucociliary clearance of aerosolized uridine 5'-triphosphate +/- amiloride in normal human adults.

1996 • 123 citations

UDP activates a mucosal-restricted receptor on human nasal epithelial cells that is distinct from the P2Y ₂ receptor

1997 • 113 citations

Rheological properties of microliter quantities of normal mucus

1977 • 103 citations

Primary Ciliary Dyskinesia (Immotile Cilia Syndrome—Kartagener Syndrome)

2005 • 97 citations

Primary Ciliary Dyskinesia: Cytological and Clinical Features

1988 • 95 citations

Sampling Technique and Rheology of Human Tracheobronchial Mucus

1988 • 66 citations

Immotile cilia syndrome in persons with and without Kartagener's syndrome.

1980 • 64 citations

Relationship between Tracheobronchial Particle Clearance Rates and Sites of Initial Deposition in Man

1989 • 63 citations

Mucus transport by cough

1981 • 58 citations

Effect of extracellular ATP and UTP on fluid transport by human nasal epithelial cells in culture.

1994 • 44 citations

Measurements of tracheobronchial clearance in patients with immotile-cilia syndrome and its value in differential diagnosis.

1983 • 39 citations

Production of 99mTc-labeled iron oxide aerosols for human lung deposition and clearance studies

1980 • 36 citations

Rheology of sputum collected by a simple technique limiting salivary contamination.

1984 • 35 citations

Ciliary Defects: Cell Biology and Clinical Perspectives

1988 • 28 citations

AEROSOL DELIVERY IN INFANTS AND YOUNG CHILDREN

1993 • 14 citations

Minireview: How Important is Mucociliary Clearance?

1988 • 11 citations