The natural interleukin-1 receptor antagonist prevents interleukin-l-induced preterm delivery in mice

Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia

1987 • 2,492 citations

Passive Immunization Against Cachectin/Tumor Necrosis Factor Protects Mice from Lethal Effect of Endotoxin

1985 • 2,380 citations

Interleukin-1 and interleukin-1 antagonism

1991 • 2,276 citations

Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonist

1990 • 1,095 citations

Interleukin-1 receptor antagonist reduces mortality from endotoxin shock

1990 • 865 citations

Purification, cloning, expression and biological characterization of an interleukin-1 receptor antagonist protein

1990 • 609 citations

Infection and labor

1989 • 600 citations

Infection and labor

1992 • 593 citations

Biological properties of recombinant human monocyte-derived interleukin 1 receptor antagonist.

1990 • 569 citations

A specific receptor antagonist for interleukin 1 prevents Escherichia coli ‐induced shock in rabbits

1991 • 435 citations

Interleukin‐1α and Interleukin‐1 β in Preterm and Term Human Parturition

1992 • 390 citations

Interleukin-1 receptor blockade improves survival and hemodynamic performance in Escherichia coli septic shock, but fails to alter host responses to sublethal endotoxemia.

1992 • 338 citations

Systemic administration of interleukin-1 induces preterm parturition in mice

1991 • 333 citations

Interlukin-1 stimulates prostaglandin biosynthesis by human amnion

1989 • 301 citations

A recombinant human receptor antagonist to interleukin 1 improves survival after lethal endotoxemia in mice.

1991 • 298 citations

Inhibition of interleukin 1 (IL-1) binding and bioactivity in vitro and modulation of acute inflammation in vivo by IL-1 receptor antagonist and anti-IL-1 receptor monoclonal antibody.

1991 • 295 citations

Interleukin-1β, human leukocyte antigen HLA-DRα, and transforming growth factor-β expression in endom trium, placenta, and placental membranes

1990 • 248 citations

Interleukin 1 receptor antagonist is a member of the interleukin 1 gene family: evolution of a cytokine control mechanism.

1991 • 243 citations

Interleukin-6 stimulates prostaglandin production by human amnion and decidual cells

1991 • 232 citations

Human decidua: a source of interleukin-1.

1989 • 221 citations

Prostaglandin E2 and collagenase production by fibroblasts and synovial cells is regulated by urine-derived human interleukin 1 and inhibitor(s).

1986 • 211 citations

Prostaglandin biosynthesis by human decidual cells: Effects of inflammatory mediators

1990 • 197 citations

Bacterial endotoxin and tumor necrosis factor stimulate prostaglandin production by human decidua

1989 • 143 citations