Interactions of antitumor agents ametantrone∗∗Trade name for the salt of 1,4-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione (Fig. 1, I). Abbreviations: HAQ, ANT; NSC-287513. and mitoxantrone (novatrone)††Trade name for the salt of 1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino] -9,10- anthracenedione (Fig. 1, II). Abbreviation: DHAQ; NSC-279836 and NSC-301739. with double-stranded DNA

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1974 • 2,905 citations

The molecular theory of polyelectrolyte solutions with applications to the electrostatic properties of polynucleotides

1978 • 2,873 citations

A fluorescent complex between ethidium bromide and nucleic acids

1967 • 2,351 citations

Structural considerations in the interaction of DNA and acridines

1961 • 2,199 citations

Ion effects on ligand-nucleic acid interactions

1976 • 1,016 citations

Calculation of binding isotherms for heterogeneous polymers

1968 • 432 citations

Molecular Aspects of Anti-Cancer Drug Action

1983 • 309 citations

Antineoplastic agents. Structure-activity relationship study of bis(substituted aminoalkylamino)anthraquinones

1978 • 250 citations

Intercalation chemistry

1983 • 162 citations

Interactions of a new antitumor agent, 1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]-ethyl]amino]-9,10-anthracenedione, with nucleic acids

1981 • 149 citations

Analysis of cooperativity and ion effects in the interaction of quinacrine with DNA

1979 • 147 citations

Molecular and biochemical pharmacology of mitoxantrone

1983 • 124 citations

The solution spectroscopy of drugs and the drug-nucleic acid interactions

1979 • 96 citations

The effect of ionic strength on DNA-tigand unwinding angles for acridine and quinoline derivatives

1980 • 83 citations

Interactions of acridine orange with nucleic acids

1983 • 79 citations

DNA-Binding Specificity and RNA Polymerase Inhibitory Activity of Bis(aminoalkyl)anthraquinones and Bis(methylthio)vinylquinolinium Iodides

1982 • 52 citations

Denaturation of Nucleic Acids Induced by Intercalating Agents. Biochemical and Biophysical Properties of Acridine Orange-DNA Complexes

1984 • 37 citations

Complex formation of acridine orange with single-stranded polyriboadenylic acid and 5?-AMP: Cooperative binding and intercalation between bases

1979 • 29 citations

Dihydroxyanthraquinone and related Bis(Substituted) aminoanthraquinones: A novel class of antitumor agents

1983 • 24 citations

Binding of magnesium ions and ethidium bromide: comparison of ribosomes and free ribosomal RNA

1979 • 17 citations

Influence of mitoxantrone on nucleic acid synthesis on the T‐47D breast tumor cell line

1983 • 16 citations