Peroxidase-Catalyzed Pro- versus Antioxidant Effects of 4-Hydroxytamoxifen: Enzyme Specificity and Biochemical Sequelae

Tissue sulfhydryl groups

1959 • 25,130 citations

X-ray crystal structure of canine myeloperoxidase at 3 Å resolution

1992 • 312 citations

Tamoxifen: new membrane-mediated mechanisms of action and therapeutic advances

1994 • 116 citations

Glutathione and ascorbate reduction of the acetaminophen radical formed by peroxidase. Detection of the glutathione disulfide radical anion and the ascorbyl radical.

1990 • 78 citations

The antioxidant action of tamoxifen and its metabolites Inhibition of lipid peroxidation

1990 • 77 citations

Tamoxifen induces hepatic aneuploidy and mitotic spindle disruption after a single in vivo administration to female Sprague-Dawley rats.

1994 • 65 citations

Does tamoxifen cause cancer in humans?

1998 • 60 citations

Mechanisms of non-genotoxic carcinogenesis

1994 • 56 citations

Activation of 4-hydroxytamoxifen and the tamoxifen derivative metabolite E by uterine peroxidase to form DNA adducts: Comparison with DNA adducts formed in the uterus of Sprague-Dawley rats treated with tamoxifen

1996 • 55 citations

Detection of glutathione thiyl free radical catalyzed by prostaglandin H synthase present in keratinocytes

1989 • 52 citations

Detection and Characterization of the Electron Paramagnetic Resonance-Silent Glutathionyl-5,5-dimethyl-1-pyrrolineN-Oxide Adduct Derived from Redox Cycling of Phenoxyl Radicals in Model Systems and HL-60 Cells

1996 • 48 citations

Histochemical identification of cultured cells from human endometrium

1984 • 29 citations

The Antioxidant Action of Synthetic Oestrogens Involves Decreased Membrane Fluidity: Relevance to Their Potential Use as Anticancer and Cardioprotective Agents Compared to Tamoxifen?

1994 • 29 citations

In Vitro Effect of Estrogens on the Peroxidase Activity of Human Endometrium*

1985 • 9 citations