Endocytosis of liposomes and intracellular fate of encapsulated molecules: Encounter with a low pH compartment after internalization in coated vesicles

Phosphorus Assay in Column Chromatography

1959 • 12,895 citations

Procedure for preparation of liposomes with large internal aqueous space and high capture by reverse-phase evaporation.

1978 • 2,254 citations

Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents.

1978 • 2,146 citations

Coated pits, coated vesicles, and receptor-mediated endocytosis

1979 • 2,073 citations

Lysosomotropic agents

1974 • 1,887 citations

Comparative Properties and Methods of Preparation of Lipid Vesicles (Liposomes)

1980 • 1,491 citations

Endocytosis

1977 • 1,275 citations

Use of resonance energy transfer to monitor membrane fusion

1981 • 1,274 citations

On the entry of semliki forest virus into BHK-21 cells

1980 • 808 citations

Conjugation of antibodies with fluorochromes: Modifications to the standard methods

1976 • 757 citations

Liposome-Cell Interaction: Transfer and Intracellular Release of a Trapped Fluorescent Marker

1977 • 702 citations

Rapid acidification of endocytic vesicles containing α2-macroglobulin

1982 • 672 citations

Cell fusion by Semliki Forest, influenza, and vesicular stomatitis viruses.

1981 • 569 citations

Intracellular pH: Its Measurement, Regulation, and Utilization in Cellular Functions.

1982 • 544 citations

Preparation of unilamellar liposomes of intermediate size (0.1–0.2 μm) by a combination of reverse phase evaporation and extrusion through polycarbonate membranes

1980 • 472 citations

Serum-induced leakage of liposome contents

1980 • 467 citations

p H-Sensitive Liposomes: Possible Clinical Implications

1980 • 410 citations

INTERACTIONS OF LIPOSOMES WITH MAMMALIAN CELLS

1978 • 408 citations

Introduction of liposome-encapsulated SV40 DNA into cells.

1980 • 407 citations

Receptor-Mediated Endocytosis of Hormones in Cultured Cells

1981 • 388 citations

Targeting to cells of fluorescent liposomes covalently coupled with monoclonal antibody or protein A

1980 • 374 citations

Role of cholesterol in membranes effects on phospholipid-protein interactions, membrane permeability and enzymatic activity

1973 • 337 citations

Introduction of macromolecules into cultured mammalian cells by osmotic lysis of pinocytic vesicles

1982 • 320 citations

Carboxyfluorescein as a probe for liposome-cell interactions effect of impurities, and purification of the dye

1981 • 257 citations

Disintegration of phosphatidylcholine liposomes in plasma as a result of interaction with high-density lipoproteins

1978 • 248 citations

Antibody Targeting of Liposomes: Cell Specificity Obtained by Conjugation of F(ab′) ₂ to Vesicle Surface

1980 • 232 citations

Stability of liposomes invivo and invitro is promoted by their cholesterol content and the presence of blood cells

1979 • 228 citations

Liposomes in biological systems

1981 • 216 citations

Distribution of Enzymes Between Subcellular Fractions in Animal Tissues

1962 • 208 citations

Liposome-mediated delivery of deoxyribonucleic acid to cells: enhanced efficiency of delivery by changes in lipid composition and incubation conditions

1981 • 181 citations

Properties and Biological Effects of Liposomes and their uses in Pharmacology and Toxicology

1978 • 167 citations

Liposomes as Gene Carriers: Efficient Transformation of Mouse L Cells by Thymidine Kinase Gene

1982 • 157 citations

The introduction of enzymes into cells by means of liposomes.

1978 • 142 citations

The use of aqueous space markers to determine the mechanism of interaction between phospholipid vesicles and cells

1979 • 130 citations

Fusion between cell membrane and liposomes containing the glycoproteins of influenza virus

1980 • 129 citations

Fluorescence Techniques in the Microdetermination of Metals in Biological Materials. Utility of 2, 4-Bis-[N,N´-di-(carboxymethyl)aminomethyl] Fluorescein in the Fluorometric Estimation of Al⁺³, Alkaline Earths, Co⁺², Cu⁺², Ni⁺², and Zn⁺² in Micromolar Concentrations.

1963 • 119 citations

Reconstitution of lipid vesicles associated with HVJ (Sendai virus) sikes. Purification and some properties of vesicles containing nontoxic fragment A of diphtheria toxin.

1979 • 104 citations

The introduction of poliovirus RNA into cells via lipid vesicles (liposomes)

1979 • 102 citations

Preparation and Properties of 3,6-Dihydroxy-2,4-bis-[N-N´-di-(carboxymethyl)-aminomethyl] fluoran

1959 • 99 citations

Liposome--lymphocyte interaction: saturable sites for transfer and intracellular release of liposome contents.

1977 • 87 citations

Fluorescence studies on the mechanism of liposome-cell interactions in vitro

1980 • 80 citations

Inhibition of vesicular stomatitis virus infection by spike glycoprotein. Evidence for an intracellular, G protein-requiring step.

1980 • 72 citations

[32] Liposomes as carriers for intracellular delivery of nucleic acids

1983 • 67 citations

Cell-induced leakage of liposome contents

1981 • 65 citations

Use of lectins and polyethylene glycol for fusion of glycolipid-containing liposomes with eukaryotic cells.

1981 • 54 citations

Implantation of the isolated human erythrocyte anion channel into plasma membranes of Friend erythroleukemic cells by use of Sendai virus envelopes.

1979 • 46 citations

Degradation of Nucleic Acids by Lysosomal Extracts of Rat Liver and Ehrlich Ascites Tumor Cells

1970 • 45 citations

Adsorptive and passive pinocytic uptake

1980 • 39 citations

Amoeboid movements and cytoplasmic fragmentation of glycerinated leukocytes induced by ATP

1970 • 34 citations

INTERACTIONS OF PHOSPHOLIPID VESICLES WITH MAMMALIAN CELLS *

1978 • 30 citations

An optical technique for measurement of intracellular pH in single living cells.

1981 • 24 citations

Liposomes, drugs and immunocompetent cell functions

1982 • 21 citations

Inability of liposome encapsulated 1-β-d-arabinofuranosylcytosine nucleotides to overcome drug resistance in L1210 cells

1981 • 20 citations

Chromatographie von Polyelektrolyten V. Aminoäthyl‐Cellulose und Guanidinoäthyl‐Cellulose

1960 • 19 citations