Mechanisms and Measurement of Dyspnea in Chronic Obstructive Pulmonary Disease

The Body-Mass Index, Airflow Obstruction, Dyspnea, and Exercise Capacity Index in Chronic Obstructive Pulmonary Disease

2004 • 3,761 citations

A measure of quality of life for clinical trials in chronic lung disease.

1987 • 1,692 citations

Measurement of feelings using visual analogue scales.

1969 • 1,362 citations

The Measurement of Dyspnea

1984 • 1,291 citations

Clinical exercise testing

1976 • 1,274 citations

Combined salmeterol and fluticasone in the treatment of chronic obstructive pulmonary disease: a randomised controlled trial

2003 • 1,222 citations

Visual analogue scales: measurement of subjective phenomena.

1989 • 1,153 citations

Dyspnea Is a Better Predictor of 5-Year Survival Than Airway Obstruction in Patients With COPD

2002 • 980 citations

Significance of Respiratory Symptoms and the Diagnosis of Chronic Bronchitis in a Working Population

1959 • 923 citations

Effects of Pulmonary Rehabilitation on Physiologic and Psychosocial Outcomes in Patients with Chronic Obstructive Pulmonary Disease

1995 • 910 citations

A long-term evaluation of once-daily inhaled tiotropium in chronic obstructive pulmonary disease

2002 • 910 citations

Effects of tiotropium on lung hyperinflation, dyspnoea and exercise tolerance in COPD

2004 • 853 citations

Improved health outcomes in patients with COPD during 1 yr's treatment with tiotropium

2002 • 752 citations

Exertional Breathlessness in Patients with Chronic Airflow Limitation: The Role of Lung Hyperinflation

1993 • 549 citations

Fundamentals of scaling and psychophysics

1978 • 540 citations

Exercise Capacity and Ventilatory, Circulatory, and Symptom Limitation in Patients with Chronic Airflow Limitation

1992 • 538 citations

Effectiveness of Fluticasone Propionate and Salmeterol Combination Delivered via the Diskus Device in the Treatment of Chronic Obstructive Pulmonary Disease

2002 • 491 citations

Pathophysiology of Dyspnea

1995 • 470 citations

Dyspnoea, disability, and distance walked: comparison of estimates of exercise performance in respiratory disease.

1978 • 446 citations

Qualitative aspects of exertional breathlessness in chronic airflow limitation: pathophysiologic mechanisms.

1997 • 428 citations

Validation of a New Dyspnea Measure

1998 • 392 citations

Lung-volume reduction improves dyspnea, dynamic hyperinflation, and respiratory muscle function.

1997 • 314 citations

The clinical diagnosis of pulmonary emphysema; an experimental study.

1952 • 285 citations

Cold Facial Stimulation Reduces Breathlessness Induced in Normal Subjects

1987 • 268 citations

Measurement Properties and Interpretability of the Chronic Respiratory Disease Questionnaire (CRQ)

2005 • 257 citations

Efficacy and Safety of a Monoclonal Antibody Recognizing Interleukin-8 in COPD

2004 • 244 citations

Effect of increased lung volume on perception of breathlessness, effort, and tension

1984 • 242 citations

Descriptors of breathlessness in cardiorespiratory diseases.

1996 • 231 citations

Comparison of Clinical Dyspnea Ratings and Psychophysical Measurements of Respiratory Sensation in Obstructive Airway Disease^1–4

1987 • 223 citations

‘Air hunger’ from increased PCO2 persists after complete neuromuscular block in humans

1990 • 222 citations

Minimal important difference of the transition dyspnoea index in a multinational clinical trial

2003 • 222 citations

Symptoms and Quadriceps Fatigability after Walking and Cycling in Chronic Obstructive Pulmonary Disease

2003 • 211 citations

The impact of exercise reconditioning on breathlessness in severe chronic airflow limitation.

1995 • 208 citations

The Effect of Comprehensive Outpatient Pulmonary Rehabilitation on Dyspnea

1994 • 196 citations

Effect of Dynamic Airway Compression on Breathing Pattern and Respiratory Sensation in Severe Chronic Obstructive Pulmonary Disease^1–3

1987 • 138 citations

Symptom Intensity and Subjective Limitation to Exercise in Patients With Cardiorespiratory Disorders

1996 • 128 citations

Inspiratory muscle training in chronic airflow limitation: comparison of two different training loads with a threshold device

1994 • 127 citations

The Breathlessness, Cough, and Sputum Scale

2003 • 115 citations

A randomised trial to evaluate the self-administered standardised chronic respiratory questionnaire

2005 • 105 citations

Meaningful effect size and patterns of response of the transition dyspnea index

2003 • 82 citations

Perceived effect on shortness of breath of an acute inhalation of saline or terbutaline: variability and sensitivity of a visual analogue scale in patients with asthma or COPD

1992 • 73 citations

Health status measurement: sensitivity of the self-reported Chronic Respiratory Questionnaire (CRQ-SR) in pulmonary rehabilitation

2003 • 67 citations

Differentiation between Dyspnea and Its Affective Components

1996 • 58 citations

Target Dyspnea Ratings Predict Expected Oxygen Consumption as Well as Target Heart Rate Values

1999 • 54 citations

Continuous measurement of breathlessness during exercise: validity, reliability, and responsiveness

2001 • 51 citations

Comparison of Continuous and Discrete Measurements of Dyspnea During Exercise in Patients With COPD and Normal Subjects

2004 • 41 citations

Psychological Profile and Ventilatory Response to Inspiratory Resistive Loading

2000 • 22 citations

Measurement of Dyspnea: Clinical Ratings

2005 • 22 citations

Responsiveness of Continuous Ratings of Dyspnea during Exercise in Patients with COPD

2005 • 19 citations

Comparison between Continuous and Discrete Measurements of Breathlessness during Exercise in Normal Subjects Using a Visual Analogue Scale

1993 • 18 citations

Mechanisms and Measurement of Exertional Dyspnea

2002 • 6 citations