The Importance of Immunesenescence in the Incidence and Malignant Properties of Cancer in Hosts of Advanced Age

Cancer: Principles and Practice of Oncology.

1991 • 8,402 citations

Age Influence on the Immune System

1980 • 703 citations

Immunological studies of aging. Decreased production of and response to T cell growth factor by lymphocytes from aged humans.

1981 • 473 citations

The Immune Reaction as a Stimulator of Tumor Growth

1972 • 403 citations

Systemic alteration induced in mice by ultraviolet light irradiation and its relationship to ultraviolet carcinogenesis.

1977 • 400 citations

Regualtion of the immune response to tumor antigens. I. Immunosuppressor cells in tumor-bearing hosts.

1976 • 339 citations

Lymphocyte-induced angiogenesis: a quantitative and sensitive assay of the graft-vs.-host reaction.

1975 • 285 citations

Regulation of the immune response to tumor antigens. II. The nature of immunosuppressor cells in tumor-bearing hosts.

1976 • 239 citations

Lymphokines and aging: interleukin-2 production and activity in aged animals.

1981 • 234 citations

Further Studies on the Tumor-Specific Suppressor Cells Induced by Ultraviolet Radiation

1978 • 189 citations

Role of T cells and adherent cells in age-related decline in murine interleukin 2 production.

1982 • 153 citations

Mechanisms of syngeneic tumor rejection. Susceptibility of host-selected progressor variants to various immunological effector cells.

1982 • 135 citations

Enhancing T lymphocytes from tumor‐bearing mice suppress host resistance to a syngeneic tumor

1974 • 135 citations

Carcinogenesis and Aging

2009 • 127 citations

Interleukin 2: Biology and biochemistry

1983 • 122 citations

Survival following breast cancer surgery in the elderly

1981 • 80 citations

Wound Repair in Mice as Influenced by Age and Antimacrophage Serum

1987 • 74 citations

Breast cancer in elderly women.

1971 • 70 citations

Change of Cell-Mediated Cytotoxicity with Aging

1975 • 59 citations

Geriatric colon cancer

1973 • 55 citations

Aging, immunity, and malignancy.

1970 • 51 citations

Why Tumors Grow More Slowly in Old People<xref ref-type="fn" rid="FN3">3</xref>

1986 • 43 citations

Suppressor Factor Secreted by T-Lymphocytes From Tumor-Bearing Mice 2

1976 • 40 citations

Lymphocyte-induced angiogenesis factor is produced by L3T4+ murine T lymphocytes, and its production declines with age

1988 • 25 citations

Hormonal Influences on Growth of B16 Murine Melanoma&lt;xref ref-type="fn" rid="FN2"&gt;2&lt;/xref&gt;

1985 • 23 citations

Proliferative and cytotoxic immune functions in ageing mice. I. Sequence of decline of reactivities measured under optimal and suboptimal sensitization conditions.

1981 • 17 citations