PKC.epsilon. is involved in granulocyte-macrophage colony-stimulating factor signal transduction: Evidence from microphysiometry and antisense oligonucleotide experiments

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

The molecular heterogeneity of protein kinase C and its implications for cellular regulation

1988 • 4,243 citations

Staurosporine, a potent inhibitor of phospholipidCa++dependent protein kinase

1986 • 2,445 citations

Establishment and characterization of a unique human cell line that proliferates dependently on GM‐CSF, IL‐3, or erythropoietin

1989 • 833 citations

The structure, expression, and properties of additional members of the protein kinase C family.

1988 • 706 citations

Light-Addressable Potentiometric Sensor for Biochemical Systems

1988 • 688 citations

The cytosensor microphysiometer: biological applications of silicon technology

1992 • 631 citations

Lysosphingolipids Inhibit Protein Kinase C: Implications for the Sphingolipidoses

1987 • 593 citations

Potent selective inhibitors of protein kinase C

1989 • 482 citations

Detection of Cell-Affecting Agents with a Silicon Biosensor

1989 • 300 citations

Protein kinase C — a family affair

1989 • 289 citations

Biosensors based on the energy metabolism of living cells: The physical chemistry and cell biology of extracellular acidification

1992 • 269 citations

Isolation and characterization of PKC-L, a new member of the protein kinase C-related gene family specifically expressed in lung, skin, and heart.

1991 • 212 citations

Purification and characterization of three types of protein kinase C from rabbit brain cytosol.

1987 • 168 citations

Isolation and characterization of the epsilon subspecies of protein kinase C from rat brain.

1992 • 140 citations

Protein kinase C heterogeneity in GH4C1 rat pituitary cells. Characterization of a Ca2(+)-independent phorbol ester receptor.

1990 • 126 citations

Continuous monitoring of receptor-mediated changes in the metabolic rates of living cells.

1990 • 124 citations

Molecular cloning of mouse protein kinase C (PKC) cDNA from Swiss 3T3 fibroblasts

1988 • 122 citations

Interferon-alpha selectively activates the beta isoform of protein kinase C through phosphatidylcholine hydrolysis.

1990 • 117 citations

Distinct mechanisms of regulation of protein kinase C epsilon by hormones and phorbol diesters.

1991 • 107 citations

Purification and characterization of a calcium-unresponsive, phorbol ester/phospholipid-activated protein kinase from porcine spleen.

1990 • 85 citations

Insulin stimulates the activity of a novel protein kinase C, PKC-epsilon, in cultured fetal chick neurons.

1990 • 79 citations

Activation of distinct protein kinase C isozymes by phorbol esters: correlation with induction of interleukin 1.beta. gene expression

1989 • 73 citations

IL-1 up-regulates the expression of cytokine receptors on a factor-dependent human hemopoietic cell line, TF-1

1991 • 69 citations

A simple, sensitive, and specific assay for free choline in plasma

1975 • 57 citations

A single form of protein kinase C is expressed in bovine adrenocortical tissue, as compared to four chromatographically resolved isozymes in rat brain

1987 • 53 citations

The microphysiometer biosensor

1991 • 48 citations

Effects of excitotoxin exposure on metabolic rate of primary hippocampal cultures: application of silicon microphysiometry to neurobiology

1992 • 45 citations

The temporal relationship between phospholipase activation, diradylglycerol formation and superoxide production in the human neutrophil

1990 • 45 citations

Interleukin 3 stimulates phosphatidylcholine turnover in a mast/megakaryocyte cell line

1989 • 40 citations

Antigen-specific stimulation of T cell extracellular acidification by MHC class II-peptide complexes.

1992 • 29 citations