Cloning of the gene encoding the delta subunit of the human T-cell receptor reveals its physical organization within the alpha-subunit locus and its involvement in chromosome translocations in T-cell malignancy.

Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing

1980 • 3,476 citations

Rapid and efficient cosmid cloning

1981 • 1,897 citations

The isolation of structural genes from libraries of eucaryotic DNA

1978 • 1,877 citations

A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains

1984 • 1,262 citations

The Chromosomal Basis of Human Neoplasia

1983 • 1,121 citations

Identification of a putative second T-cell receptor

1986 • 980 citations

Polymer support oligonucleotide synthesis XVIII^1.2): use ofβ-cyanoethyi-N,N-dialkylamino-/N-morpholino phosphoramidite of deoxynucleosides for the synthesis of DNA fragments simplifying deprotection and isolation of the final product

1984 • 840 citations

Sequence relationships between putative T-cell receptor polypeptides and immunoglobulins

1984 • 719 citations

A third rearranged and expressed gene in a clone of cytotoxic T lymphocytes

1984 • 528 citations

A third type of murine T-cell receptor gene

1984 • 491 citations

A new T-cell receptor gene located within the alpha locus and expressed early in T-cell differentiation

1987 • 483 citations

New chromosomal translocations correlate with specific immunophenotypes of childhood acute lymphoblastic leukemia

1984 • 365 citations

Packaging recombinant DNA molecules into bacteriophage particles in vitro.

1977 • 343 citations

Gene for α-Chain of Human T-Cell Receptor: Location on Chromosome 14 Region Involved in T-Cell Neoplasms

1985 • 300 citations

Immunochemical Proof That a Novel Rearranging Gene Encodes the T Cell Receptor δ Subunit

1987 • 278 citations

Isolation of β-globin-related genes from a human cosmid library

1981 • 277 citations

The human T cell receptor: Appearance in ontogeny and biochemical relationship of α and β subunits on IL-2 dependent clones and T cell tumors

1983 • 264 citations

Primary structure of human T-cell receptor α-chain

1984 • 245 citations

A 14;18 and an 8;14 chromosome translocation in a cell line derived from an acute B-cell leukemia.

1984 • 227 citations

Identification of a T3-Associated γδ T Cell Receptor on Thy-1 ⁺ Dendritic Epidermal Cell Lines

1987 • 208 citations

A Common Mechanism of Chromosomal Translocation in T- and B-Cell Neoplasia

1986 • 205 citations

Human γ-chain genes are rearranged in leukaemic T cells and map to the short arm of chromosome 7

1985 • 205 citations

Organization and sequences of the variable, joining and constant region genes of the human T-cell receptor α-chain

1985 • 201 citations

Deregulation of c- myc by Translocation of the α-Locus of the T-Cell Receptor in T-Cell Leukemias

1986 • 199 citations

Characterization of T Cell Receptor Gamma Chain Expression in a Subset of Murine Thymocytes

1986 • 199 citations

Identification of Putative Human T Cell Receptor δ Complementary DNA Clones

1987 • 187 citations

The t(8; 14) chromosomal translocation occurring in B-cell malignancies results from mistakes in V–D–J joining

1986 • 184 citations

Inversion of chromosome 14 marks human T-cell chronic lymphocytic leukaemia

1984 • 174 citations

Common Region on Chromosome 14 in T-Cell Leukemia and Lymphoma

1984 • 174 citations

Locus of the α-Chain of the T-Cell Receptor Is Split by Chromosome Translocation in T-Cell Leukemias

1985 • 140 citations

Cytogenetic studies on patients with chronic T cell leukemia/lymphoma

1984 • 134 citations

Sequences and repertoire of human T cell receptor alpha chain variable region genes in mature T lymphocytes.

1986 • 132 citations

Location of Gene for β Subunit of Human T-Cell Receptor at Band 7q35, a Region Prone to Rearrangements in T Cells

1985 • 121 citations

New cosmid vectors developed for eukaryotic DNA cloning

1984 • 77 citations

Common Mechanism of Chromosome Inversion in B- and T-Cell Tumors: Relevance to Lymphoid Development

1986 • 77 citations

Human T-cell tumours containing chromosome 14 inversion or translocation with breakpoints proximal to immunoglobulin joining regions at 14q32.

1987 • 75 citations

The mechanism of chromosome 14 inversion in a human T cell lymphoma

1987 • 70 citations

Transient rearrangements of the T cell antigen receptor alpha locus in early thymocytes.

1987 • 55 citations

Alpha-chain locus of the T-cell antigen receptor is involved in the t(10;14) chromosome translocation of T-cell acute lymphocytic leukemia.

1987 • 50 citations

Promoter and enhancer elements in the rearranged alpha chain gene of the human T cell receptor.

1987 • 50 citations