Combined Biodifferentiating and Antiangiogenic Oral Metronomic Therapy is Feasible and Effective in Relapsed Solid Tumors in Children: Single-Center Pilot Study
Data up to Jan 2025
Total Citations Per Year
Abstract
References (45)
New Guidelines to Evaluate the Response to Treatment in Solid Tumors
2000 • 15,583 citations
Tumor Angiogenesis: Therapeutic Implications
1971 • 9,898 citations
Angiogenesis in cancer and other diseases
2000 • 8,734 citations
Transplacental Carcinogenesis by Stilbestrol
1971 • 2,595 citations
Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer
2004 • 2,481 citations
Revisions of the international criteria for neuroblastoma diagnosis, staging, and response to treatment.
1993 • 2,242 citations
Treatment of High-Risk Neuroblastoma with Intensive Chemotherapy, Radiotherapy, Autologous Bone Marrow Transplantation, and 13-cis-Retinoic Acid
1999 • 1,843 citations
Highly Efficacious Nontoxic Preclinical Treatment for Advanced Metastatic Breast Cancer Using Combination Oral UFT-Cyclophosphamide Metronomic Chemotherapy
2006 • 228 citations
A Feasibility Trial of Antiangiogenic (Metronomic) Chemotherapy in Pediatric Patients With Recurrent or Progressive Cancer
2005 • 194 citations
BMP-2 mediates retinoid-induced apoptosis in medulloblastoma cells through a paracrine effect
2003 • 185 citations
Phase I trial of 13-cis-retinoic acid in children with neuroblastoma following bone marrow transplantation.
1995 • 168 citations
Phase II Evaluation of Temozolomide and 13-cis-Retinoic Acid for the Treatment of Recurrent and Progressive Malignant Glioma: A North American Brain Tumor Consortium Study
2003 • 151 citations
Treatment of recurrent malignant gliomas with high-dose 13-cis-retinoic acid.
1996 • 121 citations
13‐cis‐retinoic acid (NSC 122758) in the treatment of children with metastatic neuroblastoma unresponsive to conventional chemotherapy: Report from the childrens cancer study group
1992 • 100 citations
Pioglitazone and rofecoxib combined with angiostatically scheduled trofosfamide in the treatment of far‐advanced melanoma and soft tissue sarcoma
2004 • 99 citations
All-trans-retinoic acid: a phase II Radiation Therapy Oncology Group study (RTOG 91-13) in patients with recurrent malignant astrocytoma.
1997 • 78 citations
Proangiogenic role of neutrophil-like inflammatory heterophils during neovascularization induced by growth factors and human tumor cells
2005 • 72 citations
Cancer Anti-angiogenic Therapy
2004 • 71 citations
The selective Cox-2 inhibitor Celecoxib suppresses angiogenesis and growth of secondary bone tumors: An intravital microscopy study in mice
2006 • 70 citations
All-trans retinoic acid in relapsing malignant gliomas: clinical and radiological stabilization associated with the appearance of intratumoral calcifications.
1997 • 58 citations
The treatment of recurrent cerebral gliomas with all-trans-retinoic acid (tretinoin).
1997 • 56 citations
Response and progression in recurrent malignant glioma
1999 • 53 citations
Pharmacokinetics of all-trans retinoic acid, 13-cis retinoic acid, and fenretinide in plasma and brain of Rat.
2000 • 52 citations
Regulation of the human tissue-nonspecific alkaline phosphatase gene expression by all-trans-retinoic acid in SaOS-2 osteosarcoma cell line
2005 • 51 citations
Disposition of all-trans- and 13-cis-retinoic acids and n-hydroxyethylretinamide in mice after intravenous administration.
1980 • 51 citations
A phase II study of concurrent temozolomide and cis-retinoic acid with radiation for adult patients with newly diagnosed supratentorial glioblastoma
2005 • 49 citations
Docetaxel and cyclooxygenase-2 inhibition with celecoxib for advanced non-small cell lung cancer progressing after platinum-based chemotherapy: a multicenter phase II trial
2005 • 49 citations
High cumulative rate of secondary leukemia after continuous etoposide treatment for solid tumors in children and young adults
2005 • 45 citations
Oral etoposide for recurrent/progressive sarcomas of childhood
2003 • 44 citations
Response and progression in recurrent malignant glioma
1999 • 39 citations
Treatment With Oral Etoposide for Childhood Recurrent Ependymomas
2005 • 39 citations
Fenretinide activates caspases and induces apoptosis in gliomas.
1999 • 39 citations
Differentiation of rhabdomyosarcoma cell lines using retinoic acid
2005 • 38 citations
High-Dose Chemotherapy in Childhood Brain Tumors
2004 • 28 citations
Inhibition of epidermal growth factor receptor activity by retinoic acid in glioma cells
1990 • 28 citations
Dimethyl celecoxib as a novel non–cyclooxygenase 2 therapy in the treatment of non–small cell lung cancer
2005 • 26 citations
All-trans retinoic acid and interferon-α in the treatment of a patient with resistant metastatic osteosarcoma
2000 • 24 citations
Antineovascular therapy, a novel antiangiogenic approach
2005 • 21 citations
Effects of all-trans retinoic acid on tumor recurrence and metastasis
2005 • 15 citations
Low-Dose Thalidomide for Multiple Myeloma: Interim Analysis of a Compassionate Use Program
2004 • 12 citations
Merkel Cell Carcinoma – a Rarity in the Urogenital Tract
2006 • 10 citations
EXPRESSION AND REGULATION OF THE TRANSCRIPTIONAL REPRESSOR ZNF43 IN EWING SARCOMA CELLS
2002 • 9 citations
No responses to oral etoposide in 15 patients with recurrent brain tumors
2000 • 9 citations
Contemporary therapeutic options for children with high risk neuroblastoma.
2002 • 8 citations
Relapse after High-Dose Therapy in Relapsed Ewing’s Tumor Patients: Effects of Maintenance Chemotherapy in Two Selected Patients?
2003 • 4 citations