Adjuvant Intraperitoneal 5-Fluorouracil in High-Risk Colon Cancer

Levamisole and Fluorouracil for Adjuvant Therapy of Resected Colon Carcinoma

1990 • 2,226 citations

Efficacy of adjuvant fluorouracil and folinic acid in colon cancer

1995 • 1,043 citations

Pharmacokinetic rationale for peritoneal drug administration in the treatment of ovarian cancer.

1978 • 707 citations

Tumor size, sensitivity to therapy, and design of treatment schedules.

1977 • 442 citations

A randomized controlled trial of adjuvant portal vein cytotoxic perfusion in colorectal cancer

1985 • 302 citations

Early postoperative intraperitoneal chemotherapy as an adjuvant therapy to surgery for peritoneal carcinomatosis from gastrointestinal cancer: pharmacological studies.

1990 • 245 citations

Prospective, randomized trial of intravenous versus intraperitoneal 5-fluorouracil in patients with advanced primary colon or rectal cancer.

1985 • 243 citations

No-Touch isolation technique in colon cancer: A controlled prospective trial

1988 • 239 citations

Rationale for integrating early postoperative intraperitoneal chemotherapy into the surgical treatment of gastrointestinal cancer

1991 • 230 citations

Laparotomy enhances intraperitoneal tumor growth and abrogates the antitumor effects of interleukin-2 and lymphokine-activated killer cells.

1987 • 222 citations

Adjuvant therapy of Dukes' A, B, and C adenocarcinoma of the colon with portal-vein fluorouracil hepatic infusion: preliminary results of National Surgical Adjuvant Breast and Bowel Project Protocol C-02.

1990 • 212 citations

Prospective Randomized Trial of Early Postoperative Intraperitoneal Chemotherapy as an Adjuvant to Resectable Gastric Cancer

1998 • 192 citations

Efficacy of adjuvant fluorouracil and folinic acid in colon cancer. International Multicentre Pooled Analysis of Colon Cancer Trials (IMPACT) investigators.

1995 • 184 citations

Vascularization of small liver metastases

1989 • 159 citations

Dormant liver metastases: an experimental study

1992 • 147 citations

Randomised controlled trial of adjuvant chemotherapy by portal-vein perfusion after curative resection for colorectal adenocarcinoma

1992 • 136 citations

Portal Vein Chemotherapy for Colorectal Cancer: a Meta-analysis of 4000 Patients in 10 Studies

1997 • 118 citations

Long-term results of single course of adjuvant intraportal chemotherapy for colorectal cancer

1995 • 113 citations

Adjuvant portal liver infusion in colorectal cancer with 5-fluorouracil/heparin versus urokinase versus control results of a prospective randomized clinical trial (colorectal adenocarcinoma trial I)

1990 • 106 citations

Sites of recurrent tumour after ‘curative’ colorectal surgery: Implications for adjuvant therapy

1984 • 105 citations

Combined intravenous and intraperitoneal chemotherapy with fluorouracil + leucovorin vs fluorouracil + levamisole for adjuvant therapy of resected colon carcinoma

1998 • 93 citations

Adjuvant portal-vein infusion of fluorouracil and heparin in colorectal cancer: a randomised trial

1998 • 79 citations

Prospective randomized trial of intravenous v intraperitoneal 5-FU in patients with advanced primary colon or rectal cancer.

1985 • 67 citations

Experimental and clinical status of intraperitoneal chemotherapy

1990 • 64 citations

Phase I clinical and pharmacologic study of intraperitoneal cisplatin and fluorouracil in patients with advanced intraabdominal cancer.

1990 • 52 citations

The healing of colonic anastomoses after early intraperitoneal chemotherapy: An experimental study in rats

1988 • 51 citations

The rationale behind intraperitoneal chemotherapy in gastrointestinal malignancies.

1985 • 51 citations

Incidence of free colorectal cancer cells on the peritoneal surface

1997 • 45 citations

Adjuvant intraperitoneal 5-fluorouracil and intravenous leucovorin after colorectal cancer surgery: a randomized phase II placebo-controlled study

1994 • 45 citations

A phase I trial of immediate postoperative intraperitoneal floxuridine and leucovorin plus systemic 5-fluorouracil and levamisole after resection of high risk colon cancer

1994 • 42 citations

Effect of intraperitoneal chemotherapy and fibrinolytic therapy on tumor implantation in wound sites

1996 • 41 citations

Pharmacology of intraperitoneal infusion 5-fluorouracil and mitomycin-C.

1985 • 40 citations

Combined intraperitoneal plus intravenous chemotherapy after curative resection for colonic adenocarcinoma

1995 • 26 citations

Experimental model of colon cancer

1991 • 26 citations

Long-term results of single course of adjuvant intraportal chemotherapy for colorectal cancer. Swiss Group for Clinical Cancer Research (SAKK)

1995 • 19 citations

Portal vein chemotherapy for colorectal cancer: a meta-analysis of 4000 patients in 10 studies. Liver Infusion Meta-analysis Group.

1997 • 15 citations

Kinetics of Minimal Residual Disease

1979 • 15 citations