Genetic detection of lymph node micrometastases in patients with colorectal cancer

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Cytokeratin 20 in human carcinomas. A new histodiagnostic marker detected by monoclonal antibodies.

1992 • 807 citations

Expression of CD44 variant proteins in human colorectal cancer is related to tumor progression.

1993 • 541 citations

Identification of occult micrometastases in pericolic lymph nodes of Dukes' B colorectal cancer patients using monoclonal antibodies against cytokeratin and CC49. Correlation with long-term survival

1994 • 413 citations

Prognostic importance of occult axillary lymph node micrometastases from breast cancers

1990 • 385 citations

Chemotherapy for Colorectal Cancer

1994 • 378 citations

Identification of protein IT of the intestinal cytoskeleton as a novel type I cytokeratin with unusual properties and expression patterns.

1990 • 375 citations

Detection of cancer micrometastases in lymph nodes by reverse transcriptase-polymerase chain reaction.

1995 • 366 citations

Detection of epithelial cancer cells in peripheral blood by reverse transcriptase-polymerase chain reaction

1995 • 343 citations

Genetic diagnosis of lymph-node metastasis in colorectal cancer

1995 • 289 citations

Detection of Submicroscopic Lymph Node Metastases with Polymerase Chain Reaction in Patients with Malignant Melanoma

1994 • 280 citations

Detection of breast cancer micrometastases in axillary lymph nodes by using polymerase chain reaction.

1994 • 271 citations

Detection and significance of occult axillary node metastases in patients with invasive breast cancer

1978 • 269 citations

The prognostic significance of immunohistochemically detected lymph node micrometastases in colorectal carcinoma

1994 • 246 citations

Sensitive nested reverse transcription polymerase chain reaction detection of circulating prostatic tumor cells: comparison of prostate-specific membrane antigen and prostate-specific antigen-based assays.

1994 • 241 citations

Restaging of colorectal cancer based on the identification of lymph node micrometastases through immunoperoxidase staining of CEA and cytokeratins

1991 • 233 citations

Keratin gene expression in non-epithelial tissues. Detection with polymerase chain reaction.

1993 • 208 citations

Clearance technique for the detection of lymph nodes in colorectal cancer

1986 • 186 citations

The detection of breast carcinoma micrometastases in axillary lymph nodes by means of reverse transcriptase-polymerase chain reaction

1995 • 166 citations

The molecular detection of circulating tumour cells

1995 • 148 citations

The importance of combining xylene clearance and immunohistochemistry in the accurate staging of colorectal carcinoma.

1992 • 125 citations

Genetic diagnosis identifies occult lymph node metastases undetectable by the histopathological method.

1994 • 108 citations

Prognostic factors in colorectal cancer

1992 • 107 citations

Alternatively spliced variants of the cell adhesion molecule CD44 and tumour progression in colorectal cancer

1996 • 99 citations

Detection of circulating tumour cells and nodal metastasis by reverse transcriptase-polymerase chain reaction technique.

1997 • 39 citations

Differences in Messenger RNA Expression of Carcinoembryonic Antigen in Surgical Specimens of Colorectal Carcinoma

1992 • 11 citations