Expression of the Gastric H/K-ATPase α-Subunit in the Thymus may Explain the Dominant Role of the β-Subunit in the Pathogenesis of Autoimmune Gastritis

Low avidity recognition of self-antigen by T cells permits escape from central tolerance

1995 • 415 citations

How virus induces a rapid or slow onset insulin-dependent diabetes mellitus in a transgenic model

1994 • 309 citations

Autoimmune diabetes as a consequence of locally produced interleukin-2

1992 • 242 citations

PCR. A practical approach

1992 • 226 citations

T-cell tolerance toward a transgenic beta-cell antigen and transcription of endogenous pancreatic genes in thymus.

1994 • 223 citations

Compartmentalization of MHC class II gene expression in transgenic mice

1988 • 201 citations

Organ‐specific Autoimmunity Induced by Lymphopenia

1996 • 194 citations

An autoimmune disease with multiple molecular targets abrogated by the transgenic expression of a single autoantigen in the thymus.

1993 • 168 citations

Murine autoimmune oophoritis, epididymoorchitis, and gastritis induced by day 3 thymectomy. Immunopathology.

1987 • 117 citations

Immunological function of a defined T-cell population tolerized to low-affinity self antigens

1995 • 97 citations

The parietal cell autoantibodies recognized in neonatal thymectomy-induced murine gastritis are the α and β subunits of the gastric proton pump

1991 • 97 citations

Organ‐specific autoimmunity induced by adult thymectomy and cyclophosphamide‐induced lymphopenia

1995 • 84 citations

Mechanisms of immune tolerance induction through the thymic expression of a peripheral tissue-specific protein

1995 • 74 citations

Deletion of high-avidity T cells by thymic epithelium.

1995 • 67 citations

A conserved epitope on H+,K+-adenosine triphosphatase of parietal cells discerned by a murine gastritogenic T-cell clone

1994 • 61 citations

Primary structure and functional expression of the mouse and frog alpha-subunit of the gastric H(+)-K(+)-ATPase

1995 • 49 citations

Rapid purification of the gastric H+/K+-ATPase complex by tomato-lectin affinity chromatography

1992 • 47 citations

Expression of rat gastric H+, K+-ATPase in insect cells using a double recombinant baculovirus

1994 • 4 citations