Altered expression of novel genes in the cerebral cortex following experimental brain injury

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Cluster analysis and display of genome-wide expression patterns

1998 • 16,410 citations

Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays

2000 • 3,871 citations

Genomics, gene expression and DNA arrays

2000 • 2,039 citations

A controlled cortical impact model of traumatic brain injury in the rat

1991 • 1,123 citations

The LightCycler ^TM : A Microvolume Multisample Fluorimeter with Rapid Temperature Control

1997 • 908 citations

The lack of chromosomal protein Hmg1 does not disrupt cell growth but causes lethal hypoglycaemia in newborn mice

1999 • 523 citations

Neural representations of skilled movement

2000 • 481 citations

Prolonged memory impairment in the absence of hippocampal cell death following traumatic brain injury in the rat

1990 • 411 citations

Analysis of complex brain disorders with gene expression microarrays: schizophrenia as a disease of the synapse

2001 • 393 citations

An Id-related helix-loop-helix protein encoded by a growth factor-inducible gene.

1991 • 352 citations

An evaluation of the performance of cDNA microarrays for detecting changes in global mRNA expression

2001 • 313 citations

Transthyretin

1986 • 311 citations

Novel Pharmacologic Strategies in the Treatment of Experimental Traumatic Brain Injury: 1998

1998 • 298 citations

Dynamic Regulation of RGS2 Suggests a Novel Mechanism in G-Protein Signaling and Neuronal Plasticity

1998 • 296 citations

Traumatic brain injury as a risk factor for Alzheimer's disease: a review.

2000 • 259 citations

Accumulation of Amyloid β and Tau and the Formation of Neurofilament Inclusions Following Diffuse Brain Injury in the Pig

1999 • 255 citations

Molecular Cloning and Characterization of TIEG2Reveals a New Subfamily of Transforming Growth Factor-β-inducible Sp1-like Zinc Finger-encoding Genes Involved in the Regulation of Cell Growth

1998 • 190 citations

AP-1 proteins in the adult brain: facts and fiction about effectors of neuroprotection and neurodegeneration

2001 • 190 citations

Are the Pathobiological Changes Evoked by Traumatic Brain Injury Immediate and Irreversible?

1995 • 162 citations

Reduction of Cognitive and Motor Deficits after Traumatic Brain Injury in Mice Deficient in Poly(ADP-Ribose) Polymerase

1999 • 158 citations

Regional changes in the expression of neurotrophic factors and their receptors following acute traumatic brain injury in the adult rat brain

1999 • 152 citations

Cortical Correlates of Gesture Processing: Clues to the Cerebral Mechanisms Underlying Apraxia during the Imitation of Meaningless Gestures

2001 • 129 citations

Nerve Growth Factor Attenuates Cholinergic Deficits Following Traumatic Brain Injury in Rats

1997 • 127 citations

The role of Jun transcription factor expression and phosphorylation in neuronal differentiation, neuronal cell death, and plastic adaptationsin vivo

1994 • 123 citations

Mild Experimental Brain Injury Differentially Alters the Expression of Neurotrophin and Neurotrophin Receptor mRNAs in the Hippocampus

1999 • 110 citations

Apolipoprotein E, transthyretin and actin in the CSF of Alzheimer's patients: relation with the senile plaques and cytoskeleton biochemistry

1998 • 110 citations

Spatial memory deficits, increased phosphorylation of the transcription factor CREB, and induction of the AP-1 complex following experimental brain injury

1995 • 105 citations

Increased expression of brain-derived neurotrophic factor but not neurotrophin-3 mRNA in rat brain after cortical impact injury

1996 • 103 citations

Microarray Applications in Neuroscience

2001 • 93 citations

Modification of the Cortical Impact Model To Produce Axonal Injury in the Rat Cerebral Cortex

1994 • 89 citations

Traumatic brain injury in rats results in increased expression of Gap-43 that correlates with behavioral recovery

1998 • 87 citations

Increased expression of c-fos mRNA and AP-1 transcription factors after cortical impact injury in rats

1994 • 84 citations

Traumatic brain injury as a risk factor for Alzheimer disease. Comparison of two retrospective autopsy cohorts with evaluation of ApoE genotype

2001 • 83 citations

A new approach for filtering noise from high-density oligonucleotide microarray datasets

2001 • 78 citations

Expression of Brain-Derived Neurotrophic Factor, Nerve Growth Factor, and Heat Shock Protein HSP70 Following Fluid Percussion Brain Injury in Rats

1999 • 74 citations

Changes in Gene Expression Following Traumatic Brain Injury in the Rat

1995 • 73 citations

Regionally and temporally distinct patterns of induction of c-fos, c-jun and junB mRNAs following experimental brain injury in the rat

1996 • 72 citations

Transthyretin binds amyloid β peptides, Aβ1–42 and Aβ1–40 to form complex in the autopsied human kidney – possible role of transthyretin for Aβ sequestration

2000 • 70 citations

Sphingosine-1-phosphate induces apoptosis of cultured hippocampal neurons that requires protein phosphatases and activator protein-1 complexes

1999 • 67 citations

Interaction of Transthyretin with Amyloid β‐Protein: Binding and Inhibition of Amyloid Formation

2007 • 62 citations

Cold-Injury of the Cerebral Cortex: Immunolocalization of Cellular Proteins and Blood-Brain Barrier Permeability Studies

1996 • 58 citations

Activation of Helix-Loop-Helix Proteins Id1, Id2 and Id3 during Neural Differentiation

1994 • 58 citations

Gene expression profiles during long‐term memory consolidation

2001 • 57 citations

Transcript analysis of 1003 novel yeast genes using high-throughput northern hybridizations

2001 • 48 citations

Expression of c-fos in the Hippocampus Following Mild and Moderate Fluid Percussion Brain Injury

1992 • 46 citations

Identity of nuclear high-mobility-group protein, HMG-1, and sulfoglucuronyl carbohydrate-binding protein, SBP-1, in brain

2001 • 40 citations

Patterns of immediate early gene mRNA expression following rodent and human traumatic brain injury

1999 • 32 citations

TGFβ-Inducible Early Gene (TIEG) Also Codes for Early Growth Response α (EGRα): Evidence of Multiple Transcripts from Alternate Promoters

1998 • 31 citations

Cytoskeletal Derangements Following Central Nervous System Injury: Modulation by Neurotrophic Gene Transfection

1995 • 29 citations

Differential induction of immediate early gene mRNAs following cryogenic and impact trauma with/without craniotomy in rats

1998 • 17 citations

Assignment of the mouse <i>Rbpsuh</i> gene to chromosome 5 and one processed pseudogene <i>Rbpsuh-rs3</i> to chromosome 6

2000 • 4 citations