Carbohydrate responsive element-binding protein (ChREBP): a key regulator of glucose metabolism and fat storage

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

The SREBP Pathway: Regulation of Cholesterol Metabolism by Proteolysis of a Membrane-Bound Transcription Factor

1997 • 3,702 citations

A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver

2001 • 647 citations

ADD1: a Novel Helix-Loop-Helix Transcription Factor Associated with Adipocyte Determination and Differentiation

1993 • 575 citations

Sterol Regulatory Element-binding Proteins (SREBPs): Key Regulators of Nutritional Homeostasis and Insulin Action

2000 • 518 citations

Sterol-Regulated Release of SREBP-2 from Cell Membranes Requires Two Sequential Cleavages, One Within a Transmembrane Segment

1996 • 515 citations

Sterol Resistance in CHO Cells Traced to Point Mutation in SREBP Cleavage–Activating Protein

1996 • 473 citations

Fatty Acid Regulation of Gene Transcription

2000 • 398 citations

Mechanism for Fatty Acid “Sparing” Effect on Glucose-induced Transcription

2002 • 395 citations

Glucose and cAMP regulate the L-type pyruvate kinase gene by phosphorylation/dephosphorylation of the carbohydrate response element binding protein

2001 • 364 citations

ADD1: a novel helix-loop-helix transcription factor associated with adipocyte determination and differentiation.

1993 • 351 citations

MECHANISMS BY WHICH CARBOHYDRATES REGULATE EXPRESSION OF GENES FOR GLYCOLYTIC AND LIPOGENIC ENZYMES

1997 • 350 citations

The “Thrifty Genotype” in 19981

2009 • 321 citations

REGULATION OF THE EXPRESSION OF LIPOGENIC ENZYME GENES BY CARBOHYDRATE

1997 • 294 citations

The genes of hepatic glucose metabolism.

1990 • 271 citations

Glucose Regulation of Gene Transcription

2000 • 265 citations

Cis-regulation of the L-type pyruvate kinase gene promoter by glucose, insulin and cyclic AMP

1992 • 183 citations

Dietary Regulation of Gene Expression: Enzymes Involved in Carbohydrate and Lipid Metabolism

1987 • 178 citations

Metabolic Regulation of Gene Transcription in Mammals

1995 • 160 citations

Localization of the carbohydrate response element of the rat L-type pyruvate kinase gene

1991 • 143 citations

Transcriptional Glucose Signaling through The Glucose Response Element Is Mediated by the Pentose Phosphate Pathway

1996 • 142 citations

Carbohydrate regulation of the rat L-type pyruvate kinase gene requires two nuclear factors: LF-A1 and a member of the c-myc family

1993 • 138 citations

Overweight prevalence among youth in the United States: Why so many different numbers?

1999 • 110 citations

Purification and Characterization of a Novel Xylulose 5-Phosphate-activated Protein Phosphatase Catalyzing Dephosphorylation of Fructose-6-phosphate,2-kinase:Fructose-2,6-bisphosphatase

1995 • 102 citations

Carbohydrate Regulation of Hepatic Gene Expression

1997 • 93 citations

Induction of Fatty‐Acid‐Synthase Gene Expression by Glucose in Primary Culture of Rat Hepatocytes

1995 • 92 citations

Respective roles of glucose, fructose, and insulin in the regulation of the liver-specific pyruvate kinase gene promoter.

1994 • 92 citations

Induction of fatty acid synthase and S14 gene expression by glucose, xylitol and dihydroxyacetone in cultured rat hepatocytes is closely correlated with glucose 6-phosphate concentrations

1997 • 86 citations

Glucose Regulation of Mouse S14 Gene Expression in Hepatocytes

2000 • 78 citations

Exploration of a liver-specific, glucose/insulin-responsive promoter in transgenic mice

1993 • 62 citations

Glucose-stimulated synthesis of fructose 2,6-bisphosphate in rat liver. Dephosphorylation of fructose 6-phosphate, 2-kinase:fructose 2,6-bisphosphatase and activation by a sugar phosphate

1994 • 59 citations

A Novel Factor Binding to the Glucose Response Elements of Liver Pyruvate Kinase and Fatty Acid Synthase Genes

1999 • 57 citations

The content of pentose-cycle intermediates in liver in starved, fed ad libitum and meal-fed rats

1986 • 51 citations

Characterization and Purification of Carbohydrate Response Element-Binding Protein of the Rat L-Type Pyruvate Kinase Gene Promoter

1999 • 20 citations