Biphasic redistribution of muscarinic receptor and the altered receptor phosphorylation and gene transcription are underlying mechanisms in the rat heart during sepsis
Data up to Jan 2025
Total Citations Per Year
Abstract
References (32)
Molecular Cloning: A Laboratory Manual
2001 • 133,517 citations
Sepsis and septic shock—A review of laboratory models and a proposal
1980 • 1,441 citations
Muscarinic Receptors—Characterization, coupling and function
1993 • 1,264 citations
Antagonist binding profiles of five cloned human muscarinic receptor subtypes.
1991 • 605 citations
Protein kinases that phosphorylate activated G protein‐coupled receptors
1995 • 520 citations
Muscarinic acetylcholine receptors: signal transduction through multiple effectors
1995 • 514 citations
Molecular Biology of Muscarinic Acetylcholine Receptors
1996 • 488 citations
The Role of Sequestration in G Protein-coupled Receptor Resensitization
1997 • 356 citations
Cardiac muscarinic cholinergic receptors. Biochemical identification and characterization.
1978 • 314 citations
Adenosine-5′-triphosphate
1965 • 313 citations
Dynamic Targeting of the Agonist-stimulated m2 Muscarinic Acetylcholine Receptor to Caveolae in Cardiac Myocytes
1997 • 275 citations
Primary structure of rat cardiac beta-adrenergic and muscarinic cholinergic receptors obtained by automated DNA sequence analysis: further evidence for a multigene family.
1987 • 181 citations
Internalization of the m2 Muscarinic Acetylcholine Receptor
1997 • 170 citations
Turning off the signal: mechanisms that attenuate signaling by G protein-coupled receptors
1997 • 88 citations
Synergistic Regulation of m2 Muscarinic Acetylcholine Receptor Desensitization and Sequestration by G Protein-coupled Receptor Kinase-2 and β-Arrestin-1
1997 • 77 citations
Functional and binding studies with muscarinic M2‐subtype selective antagonists
1989 • 76 citations
Initial externalization followed by internalization of beta-adrenergic receptors in rat heart during sepsis
1996 • 72 citations
Muscarinic receptor modulation of basal and beta-adrenergic stimulated function of the failing human left ventricle.
1996 • 52 citations
Characterization of the positive and negative inotropic effects of acetylcholine in the human myocardium
1995 • 46 citations
Hypermetabolism-Organ Failure Syndrome: A Metabolic Response to Injury
1989 • 44 citations
Regulation of muscarinic M2 receptors
1997 • 42 citations
A simple assay method for determination of the specific radioactivity of the γ-phosphate group of 32P-labelled ATP.
1983 • 40 citations
HYPER- AND HYPOCARDIODYNAMIC STATES ARE ASSOCIATED WITH EXTERNALIZATION AND INTERNALIZATION, RESPECTIVELY, OF α-ADRENERGIC RECEPTORS IN RAT HEART DURING SEPSIS
1997 • 32 citations
Phosphorylation of β-adrenergic receptor leads to its redistribution in rat heart during sepsis
1998 • 30 citations
Decrease in β1-adrenergic and M2-muscarinic receptor mRNA levels and unchanged accumulation of mRNAs coding for Gαi‒2 and Gαs proteins in rat cardiac hypertrophy
1995 • 28 citations
Carbachol activates a novel sodium current in isolated guinea pig ventricular myocytes via M2 muscarinic receptors.
1991 • 27 citations
Supersensitivity of the Adenylyl Cyclase System in Acute Myocardial Ischemia: Evaluation of Three Independent Mechanisms
1991 • 25 citations
β-Adrenergic and muscarinic receptor mRNA accumulation in the sinoatrial node area of adult and senescent rat hearts
1998 • 21 citations
Adrenergic and muscarinic receptor regulation and therapeutic implications in heart failure
1996 • 17 citations
Externalization and internalization of (Na+ + K+)-ATPase in rat heart during different phases of sepsis.
1993 • 10 citations
G Protein-Coupled Receptor Kinase: Phosphorylation of Muscarinic Receptors and Facilitation of Receptor Sequestration
1996 • 7 citations
G PROTEIN-COUPLED
1996 • 5 citations