Influence of conjugation of doxorubicin to transferrin on the iron uptake by K562 cells via receptor‐mediated endocytosis

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycoluril

1978 • 4,673 citations

Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome

1975 • 2,865 citations

Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome

1975 • 2,228 citations

Iron Transport and Storage Proteins

1980 • 1,183 citations

Reduction of Ribonucleotides

1979 • 1,170 citations

Human cell surface glycoprotein related to cell proliferation is the receptor for transferrin.

1981 • 685 citations

Receptor-mediated endocytosis of transferrin in K562 cells.

1983 • 576 citations

Transferrin receptor internalization sequence YXRF implicates a tight turn as the structural recognition motif for endocytosis

1990 • 508 citations

Receptor-mediated endocytosis of transferrin and the uptake of fe in K562 cells: identification of a nonlysosomal acidic compartment.

1982 • 486 citations

Iterative fractionation of recycling receptors from lysosomally destined ligands in an early sorting endosome.

1989 • 330 citations

The Reaction of Ferric Salts with Transferrin

1973 • 326 citations

Evidence of a specific complex between adriamycin and negatively-charged phospholipids

1980 • 307 citations

TRANSFERRIN AND TRANSFERRIN RECEPTORS IN CARCINOMA OF THE BREAST

1980 • 272 citations

Oxidative destruction of erythrocyte ghost membranes catalyzed by the doxorubicin-iron complex

1982 • 238 citations

Second messengers in plant growth and development

1989 • 223 citations

Identification of transferrin receptors on the surface of human cultured cells.

1979 • 185 citations

Sorting of endocytosed transferrin and asialoglycoprotein occurs immediately after internalization in HepG2 cells.

1987 • 147 citations

Cell surface actions of adriamycin

1991 • 109 citations

Demonstration of two distinct transferrin receptor recycling pathways and transferrin-independent receptor internalization in K562 cells.

1986 • 106 citations

Transferrin binding by human lymphoblastoid cell lines and other transformed cells

1980 • 100 citations

A highly cytotoxic human transferrin-ricin A chain conjugate used to select receptor-modified cells.

1984 • 94 citations

Structural basis of anthracycline selectivity for unilamellar phosphatidylcholine vesicles: an equilibrium binding study

1985 • 83 citations

Co-migration and internalization of transferrin and its receptor on K562 cells.

1983 • 82 citations

Interaction of adriamycin with negatively charged model membranes: evidence of two types of binding sites

1985 • 76 citations

Cell surface-mediated cytotoxicity of polymer-bound Adriamycin against drug-resistant hepatocytes.

1983 • 75 citations

Transferrin conjugates of adriamycin are cytotoxic without intercalating nuclear DNA.

1992 • 71 citations

Characterization of a transferrin-diphtheria toxin conjugate.

1985 • 55 citations

The release of iron and transferrin from the human melanoma cell

1991 • 53 citations

The Structure, Function, and Regulation of Transferrin Receptors

1987 • 52 citations

Cell surface effects of adriamycin and carminomycin immobilized on cross-linked polyvinyl alcohol.

1985 • 48 citations

Heterogeneity of the human transferrin receptor and use of anti‐transferrin receptor antibodies to detect tumours in vivo

1987 • 42 citations

Transferrin and iron uptake by human lymphoblastoid and K-562 cells

1981 • 41 citations

Cytotoxicity of a transferrin‐adriamycin conjugate to anthracycline‐resistant cells

1992 • 40 citations

Inhibition of transplasma membrane electron transport by transferrin-adriamycin conjugates

1992 • 33 citations

Preliminary clinical study of transferrin-adriamycin conjugate for drug delivery to acute leukemia patients.

1990 • 30 citations

Induction of erythroid differentiation in human leukemic K-562 cells by membrane-directed action of adriamycin covalently bound to microspheres.

1990 • 30 citations

Reconstitution of transferrin receptor in mixed lipid vesicles. An example of the role of elastic and electrostatic forces for protein/lipid assembly

1990 • 28 citations

Kinetics of Internalization and Cytotoxicity of Transferrin‐Neocarzinostatin Conjugate in Human Leukemia Cell Line, K562

1990 • 26 citations

Uptake and concentration of bioactive macromolecules by K562 cells via the transferrin cycle utilizing an acid-labile transferrin conjugate

1991 • 26 citations

Transverse location of anthracyclines in lipid bilayers

1990 • 21 citations

Coated endosomal vesicles: sorting and recycling compartment for transferrin in BHK cells.

1991 • 21 citations

Effects of benzyl alcohol on transferrin and low density lipoprotein receptor mediated endocytosis in leukemic guinea pig B lymphocytes

1990 • 18 citations

Recent Advances in Cancer Research: Drug Targeting Without the Use of Monoclonal Antibodies

1989 • 18 citations

Transferrin-adriamycin conjugates which inhibit tumor cell proliferation without interaction with DNA inhibit plasma membrane oxidoreductase and proton release in K562 cells.

1991 • 15 citations

The effect of anaesthetics on protein conformation in membranes as studied by the spin-labelling technique

1983 • 14 citations

Targeting of Cytotoxic Drugs by Transferrin Receptors; Selective Killing of Acute Myelogenous Leukemia Cells

1985 • 13 citations

Plasma membrane Fe₂‐transferrin reductase and iron uptake in K562 cells are not directly related

1990 • 13 citations

Characterization of the cooperative cross-linking of doxorubicin N-hydroxysuccinimide ester derivatives to water soluble proteins

1991 • 6 citations

A rapid redistribution of the transferrin receptor to the cell surface of HL-60 cells and K562 cells upon treatment with dimethyl sulfoxide due to slowing of endocytosis

1990 • 5 citations

Lipid-protein interaction in frog nerve membrane as studied by spin-labelling.

1983 • 1 citations