Enhancement of CD3‐induced activation of human intestinal intraepithelial lymphocytes by stimulation of the β₇‐containing integrin defined by HML‐1 monoclonal antibody

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

A Cell Culture Model for T Lymphocyte Clonal Anergy

1990 • 1,894 citations

CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones

1992 • 1,573 citations

Signal transduction by integrins: increased protein tyrosine phosphorylation caused by clustering of beta 1 integrins.

1991 • 713 citations

Fibronectin/integrin interaction induces tyrosine phosphorylation of a 120-kDa protein.

1991 • 578 citations

Evidence for function of Ia molecules on gut epithelial cells in man.

1987 • 521 citations

A monoclonal antibody (HML‐1) defining a novel membrane molecule present on human intestinal lymphocytes

1987 • 461 citations

Costimulation of proliferative responses of resting CD4+ T cells by the interaction of VLA-4 and VLA-5 with fibronectin or VLA-6 with laminin.

1990 • 400 citations

Analysis of T cell stimulation by superantigen plus major histocompatibility complex class II molecules or by CD3 monoclonal antibody: costimulation by purified adhesion ligands VCAM-1, ICAM-1, but not ELAM-1.

1991 • 293 citations

Activation of CD4 cells by fibronectin and anti-CD3 antibody. A synergistic effect mediated by the VLA-5 fibronectin receptor complex.

1989 • 291 citations

Antigen presentation by epithelial cells of the rat small intestine. I. Kinetics, antigen specificity and blocking by anti-Ia antisera.

1986 • 289 citations

Subsets of CD3⁺ (T cell receptor α/β or γ/δ) and CD3⁻ lymphocytes isolated from normal human gut epithelium display phenotypical features different from their counterparts in peripheral blood

1990 • 269 citations

A new surface antigen on intraepithelial lymphocytes in the intestine

1990 • 216 citations

Intestinal Intraepithelial Lymphocytes

1991 • 152 citations

Intraepithelial lymphocytes of human gut: isolation, characterisation and study of natural killer activity.

1985 • 150 citations

Ligation of VLA-4 on T cells stimulates tyrosine phosphorylation of a 105-kD protein.

1992 • 143 citations

Proliferative responses of human intraepithelial lymphocytes to various T-cell stimuli

1989 • 138 citations

Expression, function and regulation of the intercellular adhesion molecule‐1 (ICAM‐1) on human intestinal epithelial cell lines

1991 • 121 citations

Activation and signaling status of human lamina propria T lymphocytes

1991 • 102 citations

The human intraepithelial lymphocyte marker HML‐1 is an integrin consisting of a β7 subunit associated with a distinctive α chain

1992 • 101 citations

Differential responsiveness to CD3‐Ti vs. CD2‐dependent activation of human intestinal T lymphocytes

1990 • 97 citations

HML-1 antigen on mucosa-associated T cells, activated cells, and hairy leukemic cells is a new integrin containing the beta 7 subunit.

1991 • 71 citations

Identity between the novel integrin β7 subunit and an antigen found highly expressed on intraepithelial lymphocytes in the small intestine

1991 • 37 citations

Expression of the LFA‐1 β2 Integrin (CD11a/CD18) and ICAM‐1 (CD54) in Normal and Coeliac Small Bowel Mucosa

1991 • 32 citations

Down‐regulation of protein kinase C activation in human lamina propria T lymphocytes: Influence of intestinal mucosa on T cell reactivity

1991 • 29 citations