Effect of DNA repair systems on antibacterial and mutagenic activity of an antitumor protein, neocarzinostatin

Chemical Mutagens. Principles and Methods for Their Detection.

1974 • 1,473 citations

Mutagen testing using TRP+ reversion in Escherichia coli

1976 • 439 citations

The Detection of Chemical Mutagens with Enteric Bacteria

1971 • 414 citations

BASE-CHANGE MUTAGENESIS AND PROPHAGE INDUCTION IN STRAINS OF ESCHERICHIA COLI WITH DIFFERENT DNA REPAIR CAPACITIES

1970 • 405 citations

Mutagenic activities of metal compounds in bacteria

1975 • 400 citations

Time, Temperature, and Protein Synthesis: A Study of Ultraviolet-Induced Mutation in Bacteria

1956 • 307 citations

In vitro and host-mediated “rec-assay” procedures for screening chemical mutagens; and phloxine, a mutagenic red dye detected

1972 • 301 citations

NEOCARZINOSTATIN, AN ANTITUMOR ANTIBIOTIC OF HIGH MOLECULAR WEIGHT. ISOLATION, PHYSIOCHEMICAL PROPERTIES AND BIOLOGICAL ACTIVITIES.

1965 • 289 citations

A radiation-sensitive mutant of Escherichia coli

1958 • 251 citations

DIFFERENTIAL INDUCTION AND REPAIR OF ULTRAVIOLET DAMAGE LEADING TO TRUE REVERSIONS AND EXTERNAL SUPPRESSOR MUTATIONS OF AN OCHRE CODON IN ESCHERICHIA COLI B/r WP2

1967 • 190 citations

DNA strand scission by the antitumor protein neocarzinostatin

1974 • 110 citations

Mutagenicity of dichlorvos and methyl methane-sulphonate for Escherichia coli WP2 and some derivatives deficient in DNA repair

1973 • 106 citations

Induction of Renal Tumour by Streptozotocin in Rats

1967 • 104 citations

Mode of action of neocarzinostatin: Inhibition of DNA synthesis and degradation of DNA in Sarcina lutea

1966 • 94 citations

Effect of neocarzinostatin on DNA synthesis in L1210 cells.

1974 • 82 citations

Renal tumors and other lesions in rats following a single intravenous injection of daunomycin.

1972 • 70 citations

Structure of the antitumor protein neocarzinostatin

1974 • 46 citations

Neocarzinostatin-induced breakdown of deoxyribonucleic acid in HeLa-S3 cells.

1975 • 44 citations

Selective tryptophan oxidation in the antitumor protein neocarzinostatin and effects on conformation and biological activity

1974 • 41 citations

release of thymine from DNA by neocarzinostatin

1976 • 40 citations

Clinical Trials of a New Antitumor Polypeptide: Neocarzinostatin (NCS)

1969 • 39 citations

Neocarzinostatin (NSC-69856): an antitumor antibiotic effective against ascitic leukemia L1210 in mice.

1966 • 39 citations

Invasive tumors induced in rats with actinomycin D.

1970 • 38 citations

Mode of action of neocarzinostatin: Requirement of protein synthesis for neocarzinostatin-mediated DNA degradation in Sarcina lutea

1968 • 35 citations

Structure of the antitumor protein neocarzinostatin

1974 • 26 citations

Damage of mammalian cell DNA in vivo and in vitro induced by neocarzinostatin.

1974 • 17 citations

Unscheduled DNA synthesis in human lymphocytes treated with neocarzinostatin.

1975 • 15 citations

Mutagenicity of an antitumor protein, neocarzinostatin, in Escherichia coli

1977 • 6 citations

Some modifying factors on mutagenicity of a nitrofuran compound (AF2) in E. coli

1975 • 4 citations