EphB Forward Signaling Controls Directional Branch Extension and Arborization Required for Dorsal-Ventral Retinotopic Mapping

CHEMOAFFINITY IN THE ORDERLY GROWTH OF NERVE FIBER PATTERNS AND CONNECTIONS

1963 • 1,947 citations

Eph Receptors and Ligands Comprise Two Major Specificity Subclasses and Are Reciprocally Compartmentalized during Embryogenesis

1996 • 851 citations

In vitro guidance of retinal ganglion cell axons by RAGS, a 25 kDa tectal protein related to ligands for Eph receptor tyrosine kinases

1995 • 849 citations

Complementary gradients in expression and binding of ELF-1 and Mek4 in development of the topographic retinotectal projection map

1995 • 740 citations

Nuk Controls Pathfinding of Commissural Axons in the Mammalian Central Nervous System

1996 • 536 citations

Bidirectional signalling through the EPH-family receptor Nuk and its transmembrane ligands

1996 • 526 citations

Recognition of position-specific properties of tectal cell membranes by retinal axons in vitro

1987 • 486 citations

Eph Family Transmembrane Ligands Can Mediate Repulsive Guidance of Trunk Neural Crest Migration and Motor Axon Outgrowth

1997 • 477 citations

Ephrin-A5 (AL-1/RAGS) Is Essential for Proper Retinal Axon Guidance and Topographic Mapping in the Mammalian Visual System

1998 • 460 citations

Signal transduction underlying growth cone guidance by diffusible factors

1999 • 457 citations

Topographically Specific Effects of ELF-1 on Retinal Axon Guidance In Vitro and Retinal Axon Mapping In Vivo

1996 • 418 citations

Tyrosine Phosphorylation of Transmembrane Ligands for Eph Receptors

1997 • 394 citations

Development of topographic order in the mammalian retinocollicular projection

1992 • 360 citations

Modulation of EphA Receptor Function by Coexpressed EphrinA Ligands on Retinal Ganglion Cell Axons

1999 • 355 citations

Topographic Mapping from the Retina to the Midbrain Is Controlled by Relative but Not Absolute Levels of EphA Receptor Signaling

2000 • 342 citations

Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation.

1996 • 334 citations

Juxtamembrane tyrosine residues couple the Eph family receptor EphB2/Nuk to specific SH2 domain proteins in neuronal cells

1997 • 276 citations

Inaccuracies in initial growth and arborization of chick retinotectal axons followed by course corrections and axon remodeling to develop topographic order

1989 • 273 citations

Topographic Guidance Labels in a Sensory Projection to the Forebrain

1998 • 268 citations

Kinase-Dependent and Kinase-Independent Functions of EphA4 Receptors in Major Axon Tract Formation In Vivo

2001 • 257 citations

Topographic targeting errors in the retinocollicular projection and their elimination by selective ganglion cell death

1986 • 254 citations

Ephrin-B3 is the midline barrier that prevents corticospinal tract axons from recrossing, allowing for unilateral motor control

2001 • 251 citations

Shared and distinct functions of RAGS and ELF-1 in guiding retinal axons

1997 • 239 citations

Tbx5 and the Retinotectum Projection

2000 • 234 citations

Forward Signaling Mediated by Ephrin-B3 Prevents Contralateral Corticospinal Axons from Recrossing the Spinal Cord Midline

2001 • 218 citations

EphB2 Guides Axons at the Midline and Is Necessary for Normal Vestibular Function

2000 • 210 citations

Ventroptin: A BMP-4 Antagonist Expressed in a Double-Gradient Pattern in the Retina

2001 • 206 citations

Topographic-Specific Axon Branching Controlled by Ephrin-As Is the Critical Event in Retinotectal Map Development

2001 • 205 citations

Surface densities of ephrin-B1 determine EphB1-coupled activation of cell attachment through alpha vbeta 3 and alpha 5beta 1 integrins

1999 • 202 citations

In vitro experiments on axon guidance demonstrating an anterior-posterior gradient on the tectum.

1982 • 195 citations

Kinase independent function of EphB receptors in retinal axon pathfinding to the optic disc from dorsal but not ventral retina

2000 • 191 citations

Misexpression of the Emx-Related Homeobox Genes cVax and mVax2 Ventralizes the Retina and Perturbs the Retinotectal Map

1999 • 158 citations

Nck Recruitment to Eph Receptor, EphB1/ELK, Couples Ligand Activation to c-Jun Kinase

1998 • 151 citations

A POU Domain Transcription Factor–Dependent Program Regulates Axon Pathfinding in the Vertebrate Visual System

2000 • 151 citations

Graded and Lamina-Specific Distributions of Ligands of EphB Receptor Tyrosine Kinases in the Developing Retinotectal System

1997 • 150 citations

Expression and Tyrosine Phosphorylation of Eph Receptors Suggest Multiple Mechanisms in Patterning of the Visual System

1998 • 149 citations

Position-dependent properties of retinal axons and their growth cones

1985 • 148 citations

Biochemical investigations of retinotectal adhesive specificity

1977 • 138 citations

Eph Family Receptors and Their Ligands Distribute in Opposing Gradients in the Developing Mouse Retina

1996 • 137 citations

The homeodomain protein Vax2 patterns the dorsoventral and nasotemporal axes of the eye

2002 • 129 citations

Polarized Expression of the Receptor Protein Tyrosine Kinase Cek5 in the Developing Avian Visual System

1995 • 125 citations

Control of Topographic Retinal Axon Branching by Inhibitory Membrane-Bound Molecules

1994 • 122 citations

Directional cues for growing axons forming the retinotectal projection

1987 • 117 citations

The first retinal axon growth in the mouse optic chiasm: axon patterning and the cellular environment

1995 • 117 citations

Molecular Development of Sensory Maps

1999 • 113 citations

Responses of retinal axons in vivo and in vitro to position-encoding molecules in the embryonic superior colliculus

1992 • 104 citations

Reciprocal Expression of the Eph Receptor Cek5 and Its Ligand(s) in the Early Retina

1997 • 97 citations

A gradient of adhesive specificity in developing avian retina.

1976 • 88 citations

Influence of position along the medial-lateral axis of the superior colliculus on the topographic targeting and survival of retinal axons

1992 • 45 citations

Biochemical investigations of retinotectal specificity.

1977 • 6 citations