Stimulation of Glucose-6-phosphatase Gene Expression by Glucose and Fructose-2,6-bisphosphate

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1981 • 207 citations

Isolation and characterization of the gene coding for cytosolic phosphoenolpyruvate carboxykinase (GTP) from the rat.

1983 • 198 citations

Mechanism by which hyperglycemia inhibits hepatic glucose production in conscious rats. Implications for the pathophysiology of fasting hyperglycemia in diabetes.

1993 • 191 citations

Glucose stimulation of lipogenic enzyme gene expression in cultured white adipose tissue. A role for glucose 6-phosphate.

1992 • 184 citations

Regulation of the expression of the L-type pyruvate kinase gene in adult rat hepatocytes in primary culture

1989 • 176 citations

Regulation of Rat Liver Glucose-6-Phosphatase Gene Expression in Different Nutritional and Hormonal States: Gene Structure and 5′-Flanking Sequence

1996 • 165 citations

Glucose Regulates in Vivo Glucose-6-phosphatase Gene Expression in the Liver of Diabetic Rats

1996 • 164 citations

Metabolic Regulation of Gene Transcription in Mammals

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1976 • 159 citations

The Amino Acid Sequence of Rat Liver Glucokinase Deduced from Cloned cDNA

1989 • 158 citations

Overexpression of hexokinase I in isolated islets of Langerhans via recombinant adenovirus. Enhancement of glucose metabolism and insulin secretion at basal but not stimulatory glucose levels.

1994 • 151 citations

Metformin decreases gluconeogenesis by enhancing the pyruvate kinase flux in isolated rat hepatocytes

1993 • 149 citations

Isolation of the gene for murine glucose-6-phosphatase, the enzyme deficient in glycogen storage disease type 1A.

1993 • 145 citations

Transcriptional Glucose Signaling through The Glucose Response Element Is Mediated by the Pentose Phosphate Pathway

1996 • 142 citations

High levels of glucose-6-phosphatase gene and protein expression reflect an adaptive response in proliferating liver and diabetes.

1995 • 136 citations

The pyruvate kinase gene as a model for studies of glucose-dependent regulation of gene expression in the endocrine pancreatic beta-cell type.

1993 • 126 citations

Isolation of a cDNA for the Catalytic Subunit of Rat Liver Glucose-6-Phosphatase: Regulation of Gene Expression in FAO Hepatoma Cells by Insulin, Dexamethasone and cAMP

1994 • 122 citations

Glucose 6-Phosphate Produced by Glucokinase, but Not Hexokinase I, Promotes the Activation of Hepatic Glycogen Synthase

1996 • 112 citations

Differential Effects of Overexpressed Glucokinase and Hexokinase I in Isolated Islets

1996 • 108 citations

Differential Metabolic Effects of Adenovirus-mediated Glucokinase and Hexokinase I Overexpression in Rat Primary Hepatocytes

1996 • 95 citations

Respective roles of glucose, fructose, and insulin in the regulation of the liver-specific pyruvate kinase gene promoter.

1994 • 92 citations

Effect of Acute Diabetes on Rat Hepatic Glucose-6-Phosphatase Activity and Its Messenger RNA Level

1994 • 88 citations

Hepatic 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. Use of site-directed mutagenesis to evaluate the roles of His-258 and His-392 in catalysis.

1990 • 76 citations

Glucose‐dependent regulation of the <scp>l</scp> ‐pyruvate kinase gene in a hepatoma cell line is independent of insulin and cyclic AMP

1994 • 70 citations

The rat fructose-1,6-bisphosphatase gene. Structure and regulation of expression

1991 • 63 citations

Complete nucleotide and deduced amino acid sequences of rat L‐type pyruvate kinase

1986 • 62 citations

Glucose-dependent and -independent effect of insulin on gene expression

1991 • 61 citations

Rat liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. Properties of phospho- and dephospho- forms and of two mutants in which Ser32 has been changed by site-directed mutagenesis.

1992 • 60 citations

Mechanism of Abnormal Oral Glucose Tolerance of Genetically Obese fa/fa Rats

1986 • 53 citations

Stimulation of malic enzyme formation in hepatocyte culture by metabolites: Evidence favoring a nonglycolytic metabolite as the proximate induction signal

1984 • 48 citations

[5] Glucokinase of rat liver

1975 • 43 citations

Adenovirus-mediated Overexpression of Liver 6-Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase in Gluconeogenic Rat Hepatoma Cells

1995 • 37 citations

Induction by cAMP of the mRNA encoding the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) from the chicken. Identification and characterization of a cDNA clone for the enzyme.

1984 • 35 citations

Regulation of genes for glycolytic enzymes in cultured rat hepatoma cell lines

1987 • 34 citations

Fructose 2,6-bisphosphate in livers of genetically obese rats

1983 • 27 citations

Enzymatic Breakdown of Glycogen in Liver Extracts

1938 • 24 citations

Decreased responsiveness of basal gluconeogenesis to insulin action in hepatocytes isolated from genetically obese (fa/fa) Zucker rats.

1994 • 13 citations

Preface

1991 • 4 citations