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International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (Serotonin).

1994 • 2,935 citations

A family of hyperpolarization-activated mammalian cation channels

1998 • 945 citations

Direct activation of cardiac pacemaker channels by intracellular cyclic AMP

1991 • 832 citations

Identification of a Gene Encoding a Hyperpolarization-Activated Pacemaker Channel of Brain

1998 • 698 citations

A novel adenylyl cyclase-activating serotonin receptor (5-HT7) implicated in the regulation of mammalian circadian rhythms

1993 • 682 citations

Molecular cloning, characterization, and localization of a high-affinity serotonin receptor (5-HT7) activating cAMP formation.

1993 • 607 citations

Molecular and Functional Heterogeneity of Hyperpolarization-Activated Pacemaker Channels in the Mouse CNS

2000 • 605 citations

Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype.

1993 • 510 citations

Molecular identification of a hyperpolarization-activated channel in sea urchin sperm

1998 • 464 citations

Noradrenaline and serotonin selectively modulate thalamic burst firing by enhancing a hyperpolarization-activated cation current

1989 • 434 citations

Noradrenergic and serotonergic modulation of a hyperpolarization‐activated cation current in thalamic relay neurones.

1990 • 421 citations

Two pacemaker channels from human heart with profoundly different activation kinetics

1999 • 369 citations

Inhibitory actions of ZENECA ZD7288 on whole‐cell hyperpolarization activated inward current (I_f) in guinea‐pig dissociated sinoatrial node cells

1993 • 306 citations

Mechanism of block by ZD 7288 of the hyperpolarization-activated inward rectifying current in guinea pig substantia nigra neurons in vitro

1995 • 304 citations

Inward current activated during hyperpolarization in the rabbit sinoatrial node cell

1980 • 297 citations

A Novel, Potent, and Selective 5-HT₇Antagonist: (R)-3-(2-(2-(4-Methylpiperidin-1-yl)ethyl)pyrrolidine-1-sulfonyl)phenol (SB-269970)

2000 • 246 citations

Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase.

1993 • 246 citations

Direct excitation of rat spinal motoneurones by serotonin.

1990 • 204 citations

Hyperpolarization-activated cation current (Ih) in neurons of the medial nucleus of the trapezoid body: voltage-clamp analysis and enhancement by norepinephrine and cAMP suggest a modulatory mechanism in the auditory brain stem

1993 • 153 citations

Serotonin augments the cationic current Ih in central neurons

1989 • 142 citations

Ionic mechanisms mediating 5‐hydroxytryptamine‐ and noradrenaline‐evoked depolarization of adult rat facial motoneurones.

1992 • 136 citations

Function and distribution of three rat 5-hydroxytryptamine7 (5-HT7) receptor isoforms produced by alternative splicing

1998 • 125 citations

Cyclic AMP regulates an inward rectifying sodium‐potassium current in dissociated bull‐frog sympathetic neurones.

1990 • 121 citations

Serotonergic modulation of hyperpolarization‐activated current in acutely isolated rat dorsal root ganglion neurons

1999 • 119 citations

Cyclic AMP and protein kinase A mediate 5-hydroxytryptamine type 4 receptor regulation of calcium-activated potassium current in adult hippocampal neurons.

1995 • 90 citations

Functional characterization of the recombinant human 5-hydroxytryptamine7(a) receptor isoform coupled to adenylate cyclase stimulation.

1998 • 88 citations

A Novel Rat Serotonin Receptor: Primary Structure, Pharmacology, and Expression Pattern in Distinct Brain Regions

1993 • 85 citations

Effects of protein kinase inhibitors on canine Purkinje fibre pacemaker depolarization and the pacemaker current i(f).

1991 • 84 citations

Identification of 5‐hydroxytryptamine receptors positively coupled to adenylyl cyclase in rat cultured astrocytes

1997 • 83 citations

Differential control of the hyperpolarization‐activated current (i(f)) by cAMP gating and phosphatase inhibition in rabbit sino‐atrial node myocytes.

1997 • 77 citations

5‐CT stimulation of adenylyl cyclase activity in guinea‐pig hippocampus: evidence for involvement of 5‐HT₇ and 5‐HT_1A receptors

1999 • 63 citations

A 5-HT(7) receptor-mediated depolarization in the anterodorsal thalamus. I. Pharmacological characterization.

2001 • 58 citations

Activation of f‐channels by cAMP analogues in macropatches from rabbit sino‐atrial node myocytes

1997 • 55 citations

Two kinetically distinct components of hyperpolarization‐activated current in rat superior colliculus‐projecting neurons.

1993 • 50 citations

Serotonin alters an inwardly rectifying current (Ih) in rat cerebellar Purkinje cells under voltage clamp

1993 • 48 citations

Modulation of I H by 5-HT in Neonatal Rat Motoneurones In Vitro : Mediation through a Phosphorylation Independent Action of cAMP

1997 • 48 citations

Serotonin has different effects on two classes of Betz cells from the cat

1994 • 40 citations