Selective changes in mitochondria respiratory properties in oxidative or glycolytic muscle fibers isolated from G93AhumanSOD1 transgenic mice

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1993 • 6,762 citations

Motor Neuron Degeneration in Mice that Express a Human Cu,Zn Superoxide Dismutase Mutation

1994 • 3,959 citations

Oxidative damage and mitochondrial decay in aging.

1994 • 2,024 citations

MITOCHONDRIAL DNA MUTATIONS AS AN IMPORTANT CONTRIBUTOR TO AGEING AND DEGENERATIVE DISEASES

1989 • 1,179 citations

Genetic Analysis with Man–Mouse Somatic Cell Hybrids: Linkage between Human Lactate Dehydrogenase B and Peptidase B Genes

1970 • 1,148 citations

Evidence of Increased Oxidative Damage in Both Sporadic and Familial Amyotrophic Lateral Sclerosis

1997 • 792 citations

Altered Reactivity of Superoxide Dismutase in Familial Amyotrophic Lateral Sclerosis

1996 • 718 citations

Massive Mitochondrial Degeneration in Motor Neurons Triggers the Onset of Amyotrophic Lateral Sclerosis in Mice Expressing a Mutant SOD1

1998 • 706 citations

Early and Selective Loss of Neuromuscular Synapse Subtypes with Low Sprouting Competence in Motoneuron Diseases

2000 • 645 citations

Mitochondrial disease in mouse results in increased oxidative stress

1999 • 634 citations

Superoxide Dismutase Activity, Oxidative Damage, and Mitochondrial Energy Metabolism in Familial and Sporadic Amyotrophic Lateral Sclerosis

1993 • 627 citations

Mitochondrial disease in superoxide dismutase 2 mutant mice

1999 • 581 citations

A gain-of-function of an amyotrophic lateral sclerosis-associated Cu,Zn-superoxide dismutase mutant: An enhancement of free radical formation due to a decrease in Km for hydrogen peroxide.

1996 • 464 citations

Mitochondrial respiratory parameters in cardiac tissue: A novel method of assessment by using saponin-skinned fibers

1987 • 342 citations

Copper, zinc superoxide dismutase catalyzes hydroxyl radical production from hydrogen peroxide.

1990 • 336 citations

Mitochondrial DNA abnormalities in skeletal muscle of patients with sporadic amyotrophic lateral sclerosis

2000 • 252 citations

Impairment of mitochondrial function in skeletal muscle of patients with amyotrophic lateral sclerosis

1998 • 249 citations

Muscle Creatine Kinase-deficient Mice

1995 • 173 citations

Ultrastructural study of synapses in the anterior horn neurons of patients with amyotrophic lateral sclerosis

1996 • 170 citations

Muscle Creatine Kinase-deficient Mice

1995 • 138 citations

Metabolic Dysfunction in Familial, but Not Sporadic, Amyotrophic Lateral Sclerosis

1998 • 136 citations

Retarded diffusion of ADP in cardiomyocytes: possible role of mitochondrial outer membrane and creatine kinase in cellular regulation of oxidative phosphorylation

1993 • 134 citations

Superoxide Dismutase Concentration and Activity in Familial Amyotrophic Lateral Sclerosis

1995 • 125 citations

The age-related accumulation of a mitochondrial DNA control region mutation in muscle, but not brain, detected by a sensitive PNA-directed PCR clamping based method

2000 • 118 citations

Progressive motor neuron impairment in an animal model of familial amyotrophic lateral sclerosis

1997 • 107 citations

Oxidative stress mediates impairment of muscle function in transgenic mice with elevated level of wild-type Cu/Zn superoxide dismutase

1997 • 105 citations

Superoxide dismutase in familial amyotrophic lateral sclerosis: models for gain of function

1995 • 59 citations

Spontaneous myopathy in the SJL/J mouse: Pathology and strength loss

1997 • 58 citations

Copper/zinc superoxide dismutase mRNA levels are increased in sporadic amyotrophic lateral sclerosis motorneurons

1994 • 42 citations

CuZnSOD and MnSOD immunoreactivity in brain stem motor neurons from amyotropic lateral sclerosis patients

1998 • 28 citations

Maintained Coupling of Oxidative Phosphorylation to Creatine Kinase Activity in Sarcomeric Mitochondrial Creatine Kinase-deficient Mice

1998 • 26 citations

The free radical‐generating function of a familial amyotrophic lateral sclerosis‐associated D90A Cu,Zn‐superoxide dismutase mutant

1998 • 9 citations

Deleted Work

1955 • 0 citations