In vivo upregulation of the blood–brain barrier GLUT1 glucose transporter by brain-derived peptides

Brain-type glucose transporter (GLUT-1) is selectively localized to the blood-brain barrier. Studies with quantitative western blotting and in situ hybridization.

1990 • 581 citations

An in situ brain perfusion technique to study cerebrovascular transport in the rat

1984 • 538 citations

Brain Glucose Uptake and Unawareness of Hypoglycemia in Patients with Insulin-Dependent Diabetes Mellitus

1995 • 220 citations

Reversibility of Unawareness of Hypoglycemia in Patients with Insulinomas

1993 • 219 citations

Hypoxia-inducible Protein Binding to Vascular Endothelial Growth Factor mRNA and Its Modulation by the von Hippel-Lindau Protein

1996 • 212 citations

Glucose transporter localization in brain using light and electron immunocytochemistry

1989 • 202 citations

Ectopic Expression of Hel-N1, an RNA-Binding Protein, Increases Glucose Transporter (GLUT1) Expression in 3T3-L1 Adipocytes

1997 • 200 citations

Distribution of glucose transporter messenger RNA transcripts in tissues of rat and man.

1987 • 190 citations

Erythrocyte/HEPG2-type glucose transporter is concentrated in cells of blood-tissue barriers

1990 • 162 citations

Upregulation of Blood-Brain Barrier GLUT1 Glucose Transporter Protein and mRNA in Experimental Chronic Hypoglycemia

1995 • 158 citations

Gene expression of GLUT3 and GLUT1 glucose transporters in human brain tumors

1994 • 157 citations

Glucose Deprivation Causes Posttranscriptional Enhancement of Brain Capillary Endothelial Glucose Transporter Gene Expression via GLUT1 mRNA Stabilization

1993 • 121 citations

Glucose Availability to Individual Cerebral Structures Is Correlated to Glucose Metabolism

1983 • 115 citations

The brain-type glucose transporter mRNA is specifically expressed at the blood-brain barrier

1990 • 114 citations

Tumor necrosis factor alpha-induced glucose transporter (GLUT-1) mRNA stabilization in 3T3-L1 preadipocytes. Regulation by the adenosine-uridine binding factor.

1992 • 112 citations

Efficacy of the Peptidergic Nootropic Drug Cerebrolysin in Patients with Senile Dementia of the Alzheimer Type (SDAT)

1994 • 107 citations

The Interaction of Transport and Metabolism on Brain Glucose Utilization: A Reevaluation of the Lumped Constant

1981 • 100 citations

Up‐Regulation of Blood‐Brain Barrier Short‐Form Leptin Receptor Gene Products in Rats Fed a High Fat Diet

1998 • 96 citations

The antidiabetic agent pioglitazone increases expression of glucose transporters in 3T3-F442A cells by increasing messenger ribonucleic acid transcript stability.

1993 • 84 citations

Neurotrophic factor-like effect of FPF1070 on septal cholinergic neurons after transections of fimbria-fornix in the rat brain.

1992 • 82 citations

Molecular cloning of the bovine blood-brain barrier glucose transporter cDNA and demonstration of phylogenetic conservation of the 5′-untranslated region

1990 • 82 citations

Nerve growth factor and nootropic drug Cerebrolysin but not fibroblast growth factor can reduce spatial memory impairment elicited by fimbria-fornix transection: short-term study

1996 • 64 citations

Cerebrolysin Ameliorates Performance Deficits, and Neuronal Damage in Apolipoprotein E-Deficient Mice

1999 • 63 citations

A One‐Step Procedure for Isolation of Poly(A)⁺ mRNA from Isolated Brain Capillaries and Endothelial Cells in Culture

1991 • 63 citations

Ten nucleotide cis element in the 3′-untranslated region of the GLUT1 glucose transporter mRNA increases gene expression via mRNA stabilization

1998 • 58 citations

Tumor Necrosis Factor-α Regulation of Glucose Transporter (GLUT1) mRNA Turnover

1997 • 51 citations

Cis‐Element/Cytoplasmic Protein Interaction Within the 3′‐Untranslated Region of the GLUT1 Glucose Transporter mRNA

1996 • 45 citations

Enhanced expression of the blood-brain barrier GLUT1 glucose transporter gene by brain-derived factors

1994 • 43 citations

Upregulation of blood-brain barrier GLUT1 glucose transporter protein and mRNA in experimental chronic hypoglycemia

1995 • 43 citations

Brain-derived peptides regulate the steady state levels and increase stability of the blood-brain barrier GLUT1 glucose transporter mRNA

1995 • 41 citations

Differential expression in glioblastoma multiforme and cerebral hemangioblastoma of cytoplasmic proteins that bind two different domains within the 3'-untranslated region of the human glucose transporter 1 (GLUT1) messenger RNA.

1996 • 40 citations

Blood–brain barrier methodology and biology

1998 • 39 citations

[Protective effect of FPF 1070 (cerebrolysin) on delayed neuronal death in the gerbil--detection of hydroxyl radicals with salicylic acid].

1993 • 35 citations

The antidiabetic agent pioglitazone increases expression of glucose transporters in 3T3-F442A cells by increasing messenger ribonucleic acid transcript stability

1993 • 24 citations

Morphofunctional effects of moderate forebrain ischemia combined with short-term hypoxia in rats — protective effects of Cerebrolysin

1997 • 24 citations

GLUT1 glucose transporter: differential gene transcription and mRNA binding to cytosolic and polysome proteins in brain and peripheral tissues

1998 • 24 citations

The effect of MK-801 and of brain-derived polypeptides on the development of ischemic lesion induced by photothrombotic occlusion of the distal middle cerebral artery in rats

1998 • 23 citations

The influence of Cerebrolysin® and E021 on spatial navigation of 24-month-old rats

1998 • 21 citations

Brain-derived peptides increase blood–brain barrier GLUT1 glucose transporter gene expression via mRNA stabilization

1998 • 19 citations

Site‐Directed Deletion of a 10‐Nucleotide Domain of the 3′‐Untranslated Region of the GLUT1 Glucose Transporter mRNA Eliminates Cytosolic Protein Binding in Human Brain Tumors and Induction of Reporter Gene Expression

1997 • 15 citations

Molecular regulation of the blood-brain barrier GLUT1 glucose transporter by brain-derived factors

1998 • 13 citations

Dose-dependent effects of Cerebrolysin® on EEG and short term memory of healthy volunteers during control and hyperventilation induced cerebral ischemia

1998 • 11 citations

Molecular biology of brain capillaries

1998 • 7 citations