Molecular analysis of HLA class I and class II antigen loss mutants reveals a homozygous deletion of the DR, DQ, and part of the DP region: Implications for class II gene order

Immune interferon activates multiple class II major histocompatibility complex genes and the associated invariant chain gene in human endothelial cells and dermal fibroblasts.

1984 • 579 citations

Structure, Sequence and Polymorphism in the HLA‐D Region

1985 • 302 citations

Gamma ray-induced loss of expression of HLA and glyoxalase I alleles in lymphoblastoid cells.

1980 • 257 citations

Mutations and selection in the generation of class II histocompatibility antigen polymorphism.

1984 • 232 citations

Human B cell variants immunoselected against a single Ia antigen subset have lost expression of several Ia antigen subsets.

1983 • 205 citations

Homozygous deletions that simultaneously eliminate expressions of class I and class II antigens of EBV-transformed B-lymphoblastoid cells. I. Reduced proliferative responses of autologous and allogeneic T cells to mutant cells that have decreased expression of class II antigens

1984 • 187 citations

Structural organization of the DR subregion of the human major histocompatibility complex.

1985 • 173 citations

Six HLA-D region alpha-chain genes on human chromosome 6: polymorphisms and associations of DC alpha-related sequences with DR types.

1984 • 163 citations

Complete nucleotide sequence of a functional HLA-DPβ gene and the region between the DPβ1 and DPα1 genes: comparison of the 5′ ends of HLA class II genes

1985 • 132 citations

Linkage map of two HLA-SBβ and two HLA-SBα-related genes: an intron in one of the SBβ genes contains a processed pseudogene

1984 • 109 citations

DNA sequence and characterization of human class II major histocompatibility complex beta chains from the DR1 haplotype.

1985 • 109 citations

Specificity of monoclonal antibodies directed against human and murine class II histocompatibility antigens as analyzed by binding to HLA-deletion mutant cell lines

1985 • 106 citations

SB: a new HLA-linked human histocompatibility gene defined using HLA-mutant cell lines

1981 • 93 citations

Molecular map of the human HLA-SB (HLA-DP) region and sequence of an SB alpha (DP alpha) pseudogene.

1984 • 84 citations

SB subregion of the human major histocompatibility complex: gene organization, allelic polymorphism and expression in transformed cells.

1985 • 79 citations

Identification of a trans-acting function regulating HLA-DR expression in a DR-negative B cell variant

1980 • 78 citations

A minimum of four human class II α-chain genes are encoded in the HLA region of chromosome 6

1983 • 77 citations

Dissection of the D-region of the human major histocompatibility complex by means of induced mutations in a lymphoblastoid cell line

1983 • 76 citations

Nomenclature for factors of the HLA system 1984

1984 • 75 citations

Molecular localization of human class II MT2 and MT3 determinants.

1984 • 72 citations

Isolation of a cDNA clone for the human HLA-DR antigen alpha chain by using a synthetic oligonucleotide as a hybridization probe.

1982 • 63 citations

Transfer of cloned human class I major histocompatibility complex genes into HLA mutant human lymphoblastoid cells.

1986 • 60 citations

Serological and immunochemical analysis of the products of a single HLA DR-alpha and DR-beta chain gene expressed in a mouse cell line after DNA-mediated cotransformation reveals that the beta chain carries a known supertypic specificity.

1985 • 51 citations

Mapping of class I DNA sequences within the human major histocompatibility complex

1983 • 50 citations

The gene encoding the human class II antigen-associated ? chain is located on chromosome 5

1984 • 46 citations

In search of a function for the invariant chain associated with la antigens

1985 • 43 citations

Polymorphic restriction endonuclease sites linked to the HLA-DR alpha gene: localization and use as genetic markers of insulin-dependent diabetes.

1985 • 41 citations

Localization of the human MHC-linked complement genes between HLA-B and HLA-DR by using HLA mutant cell lines.

1985 • 40 citations

Identification of a human Ia antigen that is different from HLA-DR and DC antigens

1983 • 33 citations

Mapping of the genes encoding the HLA-DR alpha chain and the HLA-related antigens to a chromosome 6 deletion by using genomic blotting.

1983 • 27 citations

Dissociation in expression of MB1/MT1 and DR1 alloantigens in mutants of a lymphoblastoid cell line.

1983 • 22 citations

Analysis by molecular cloning of the human class II genes.

1984 • 20 citations

The proliferative immune response to autologous Epstein-Barr virus-transformed lymphoblastoid cells. I. Studies with HLA haplotype loss variants demonstrate a role for MHC-linked genes

1985 • 10 citations

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