All-trans-Retinoic Acid Inhibits Jun N-terminal Kinase-dependent Signaling Pathways

Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation

1995 • 4,589 citations

The RXR heterodimers and orphan receptors

1995 • 3,168 citations

The Regulation of AP-1 Activity by Mitogen-activated Protein Kinases

1995 • 2,441 citations

Activation of the Estrogen Receptor Through Phosphorylation by Mitogen-Activated Protein Kinase

1995 • 1,973 citations

9-cis retinoic acid is a high affinity ligand for the retinoid X receptor

1992 • 1,790 citations

TISSUE CHANGES FOLLOWING DEPRIVATION OF FAT-SOLUBLE A VITAMIN

1925 • 1,630 citations

Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

1995 • 1,499 citations

The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain

1993 • 1,313 citations

9-Cis retinoic acid stereoisomer binds and activates the nuclear receptor RXRα

1992 • 1,252 citations

Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun

1994 • 978 citations

Integration of MAP Kinase Signal Transduction Pathways at the Serum Response Element

1995 • 935 citations

ERK phosphorylation potentiates Elk-1-mediated ternary complex formation and transactivation.

1995 • 667 citations

Type beta transforming growth factor is the primary differentiation-inducing serum factor for normal human bronchial epithelial cells.

1986 • 570 citations

A serum-free method for culturing normal human bronchial epithelial cells at clonal density

1985 • 344 citations

Retinoids Selective for Retinoid X Receptor Response Pathways

1992 • 342 citations

A retinoic acid receptor alpha antagonist selectively counteracts retinoic acid effects.

1992 • 256 citations

Activation of Retinoid X Receptors Induces Apoptosis in HL-60 Cell Lines

1995 • 247 citations

Regulation of proliferation and differentiation of respiratory tract epithelial cells by TGFβ

1986 • 166 citations

Activation of specific RXR heterodimers by an antagonist of RXR homodimers

1996 • 164 citations

Control of growth regulatory and differentiation-specific genes in human epidermal keratinocytes by interferon gamma. Antagonism by retinoic acid and transforming growth factor beta 1.

1994 • 151 citations

Isomerization of all-trans-retinoic acid to 9-cis-retinoic acid

1994 • 130 citations

Identification of retinoids with nuclear receptor subtype-selective activities.

1991 • 105 citations

All-trans-retinoic Acid Increases Transforming Growth Factor-β2 and Insulin-like Growth Factor Binding Protein-3 Expression through a Retinoic Acid Receptor-α-dependent Signaling Pathway

1997 • 94 citations

Retinoic acid and substratum regulate the differentiation of rabbit tracheal epithelial cells into squamous and secretory phenotype. Morphological and biochemical characterization.

1987 • 83 citations

Conformational Effects on Retinoid Receptor Selectivity. 2. Effects of Retinoid Bridging Group on Retinoid X Receptor Activity and Selectivity

1995 • 81 citations

Squamous Metaplasia in Organ Cultures of Vitamin A-Deficient Hamster Trachea: Cytokinetic and Ultrastructural Alterations<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1982 • 67 citations

Constitutively active mitogen-activated protein kinase kinase 1 (MAPKK1) and MAPKK2 mediate similar transcriptional and morphological responses.

1996 • 62 citations

Retinoids Increase Human Apolipoprotein A-II Expression through Activation of the Retinoid X Receptor but Not the Retinoic Acid Receptor

1996 • 60 citations

Differential effects of 12-O-tetradecanoylphorbol-13-acetate on cultured normal and neoplastic human bronchial epithelial cells.

1984 • 58 citations

Retinoid refractoriness occurs during lung carcinogenesis despite functional retinoid receptors

1996 • 54 citations

Functional dissection in vitro of the human c-fos promoter.

1991 • 49 citations

Retinoic acid receptor- and retinoid X receptor-selective retinoids activate signaling pathways that converge on AP-1 and inhibit squamous differentiation in human bronchial epithelial cells.

1996 • 44 citations

Nuclear retinoic acid receptor characterization in cultured human trophoblast cells: effect of retinoic acid on epidermal growth factor receptor expression

1994 • 40 citations

Regulation of differentiation of airway epithelial cells by retinoids

1986 • 39 citations

Retinoid X receptor-specific retinoids inhibit the ability of retinoic acid receptor-specific retinoids to increase the level of insulin-like growth factor binding protein-3 in human ectocervical epithelial cells.

1996 • 38 citations

Differential regulation of human ectocervical epithelial cell line proliferation and differentiation by retinoid X receptor- and retinoic acid receptor-specific retinoids.

1996 • 34 citations

Retinoic acid suppresses polyoma virus transformation by inhibiting transcription of the c-fos proto-oncogene.

1994 • 28 citations

Inhibition of epidermal growth factor-like growth factor secretion in tracheobronchial epithelial cells by vitamin A.

1993 • 21 citations

All-trans-retinoic acid and hexamethylene bisacetamide (HMBA) regulate TGF-α and Hst-1/kFGF expression in differentiation sensitive but not in resistant human teratocarcinomas

1994 • 20 citations

Determination of the Promoter Elements That Mediate Repression of c-fos Gene Transcription by Thyroid Hormone and Retinoic Acid Receptors

1994 • 14 citations

Retroviral gene transfer of epidermal growth factor receptor into HL60 cells results in a partial block of retinoic acid-induced granulocytic differentiation.

1993 • 14 citations

Regulation of retinoid-induced differentiation in embryonal carcinoma PCC4.aza1R cells: effects of retinoid-receptor selective ligands.

1996 • 10 citations

Inhibition of TGF-alpha gene expression by vitamin A in airway epithelium.

1996 • 8 citations