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Some studies of the active intermediates formed in the microsomal metabolism of cyclophosphamide and isophosphamide

Data up to Jan 2025

Published1974
Citations347
References21

Total Citations Per Year

Abstract

References (21)

1,2-Naphthalene oxide as an intermediate in the microsomal hydroxylation of naphthalene. V

1970 • 428 citations

Use of γ-(4-Nitrobenzyl)pyridine as Analytical Reagent for Ethylenimines and Alkylating Agents

1955 • 348 citations

Studies on the mechanism of action of cytoxan. Evidence of activation in vivo and in vitro.

1961 • 190 citations

Enzymatic metabolism of cyclophosphamide and nicotine and production of a toxic cyclophosphamide metabolite.

1972 • 183 citations

Synthese und Abbau cytostatisch wirksamer cyclischer N‐Phosphamidester des Bis‐(β‐chloräthyl)‐amins

1958 • 161 citations

THE IDENTIFICATION OF CARBONYL COMPOUNDS BY USE OF 2,4-DINITROPHENYLHYDRAZINE

1930 • 148 citations

Cyclophosphamide metabolites and their related compounds. II. Preparation of an active species of cyclophosphamide and some related compounds

1973 • 81 citations

Comparison of nitrogen‐mustard‐sensitive and ‐resistant yoshida sarcomas

1966 • 77 citations

THE DIAZOMETHOLYSIS OF GLYCEROLPHOSPHATIDES. A NOVEL METHOD OF DETERMINING THE CONFIGURATION OF PHOSPHATIDYL SERINES AND CEPHALINS

1955 • 58 citations

Metabolism of cyclophosphamide by sheep

1972 • 57 citations

Isophosphamide as a new acrolein-producing antineoplastic isomer of cyclophosphamide.

1972 • 56 citations

Microsomal activation of cyclophosphamide in vivo

1970 • 49 citations

Studies on Cyclophosphamide Metabolites and Their Related Compounds. I

1972 • 41 citations

Effect of deuteration of the OCH3 group on the enzymic demethylation of o-nitroanisole☆

1967 • 40 citations

Cytotoxic drugs in the treatment of cancer

1969 • 34 citations

Cytotoxic Drugs in the Treatment of Cancer

1970 • 30 citations

Zur Massenspektrometrie von Nitrophenylverbindungen—II. Nitrophenylhydrazone Aliphatischer Aldehyde und Ketone

1970 • 26 citations

Observations on the metabolism of cyclophosphamide

1972 • 23 citations

Chemical trapping of a reactive metabolite

1972 • 23 citations

PRECLINICAL INVESTIGATION OF ALKYLATING AGENTS IN CANCER CHEMOTHERAPY

1969 • 21 citations

Crystal and molecular structure of cyclophosphamide hydrate

1972 • 13 citations

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Some studies of the active intermediates formed in the microsomal metabolism of… (1974) – Biochemical Pharmacology | Metascience Observatory Explorer