Development of monoclonal antibodies to 3-hydroxy-3-methylglutaryl-coenzyme A reductase

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Continuous cultures of fused cells secreting antibody of predefined specificity

1975 • 17,037 citations

Selected methods in cellular immunology

1981 • 1,915 citations

Selected methods in cellular immunology

1980 • 747 citations

Regulation of HMG-CoA Reductase

1976 • 743 citations

Induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in human fibroblasts incubated with compactin (ML-236B), a competitive inhibitor of the reductase

1978 • 556 citations

Inhibitory Effects on Lipid Metabolismn in Cultured Cells of ML‐236B, a Potent Inhibitor of 3‐Hydroxt‐3‐methylglutaryl‐Cornzyme‐A Reductase

1978 • 252 citations

A rapid sensitive assay for specific protein synthesis in cells and in cell-free translations: Use of Staphylococcus aureus as an adsorbent for immune complexes

1979 • 145 citations

Modulation of hydroxymethylglutaryl-CoA reductase activity, reductase kinase activity, and cholesterol synthesis in rat hepatocytes in response to insulin and glucagon.

1979 • 143 citations

Localization of murine Ig-1b and Ig-1a (IgG 2a) allotypic determinants detected with monoclonal antibodies

1979 • 134 citations

Properties of purified rat hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase and regulation of enzyme activity.

1980 • 118 citations

Control of 3-hydroxy-3-methylglutaryl coenzyme A reductase by endogenously synthesized sterols in vitro and in vivo.

1977 • 110 citations

In vitro and in vivo phosphorylation of rat liver 3-hydroxy-3-methylglutaryl coenzyme A reductase and its modulation by glucagon.

1980 • 96 citations

Radioimmune precipitation of 3-hydroxy-3-methylglutaryl coenzyme A reductase from Chinese hamster fibroblasts. Effect of 25-hydroxycholesterol.

1981 • 93 citations

3-Hydroxy-3-methylglutaryl coenzyme A reductase from rat liver. Its purification, properties, and immunochemical studies.

1976 • 72 citations

The in vivo regulation of rat liver 3-hydroxy-3-methylglutaryl coenzyme A reductase. Phosphorylation of the enzyme as an early regulatory response following cholesterol feeding.

1981 • 67 citations

Proteinase involvement in the solubilization of 3-hydroxy-3-methylglutaryl coenzyme a reductase

1981 • 57 citations

In vivo and in vitro mechanisms regulating rat liver beta-hydroxy-beta-methylglutaryl coenzyme A reductase activity.

1980 • 52 citations

Purification of 3-hydroxy-3-methylglutaryl coenzyme A reductase from rat liver

1979 • 49 citations

Regulation of 3-hydroxy-3-methylglutaryl coenzyme a reductase in minimal deviation hepatoma 7288C. Immunological measurements in hepatoma tissue culture cells.

1977 • 46 citations

An alternate method of purification and properties of rat liver beta-hydroxy-beta-methylglutaryl coenzyme A reductase.

1979 • 27 citations

Purification and properties of rat liver 3-hydroxy-3-methylglutaryl coenzyme A reductase

1979 • 22 citations

Cholesterol Metabolism and Lipolytic Enzymes

1979 • 15 citations