Kinetics of binding of [3H]acetylcholine and [3H]carbamoylcholine to Torpedo postsynaptic membranes: slow conformational transitions of the cholinergic receptor

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

A study of the ‘desensitization’ produced by acetylcholine at the motor end‐plate

1957 • 1,457 citations

Structural and Functional Properties of the Acetylcholine Receptor Protein in its Purified and Membrane-Bound States

1978 • 399 citations

Large‐Scale Purification of the Acetylcholine‐Receptor Protein in Its Membrane‐Bound and Detergent‐Extracted Forms from Torpedo marmorata Electric Organ

1977 • 375 citations

Acetylcholine and local anesthetic binding to Torpedo nicotinic postsynaptic membranes after removal of nonreceptor peptides.

1979 • 350 citations

On the mechanism of desensitization at cholinergic receptors.

1970 • 247 citations

Equilibrium binding of [3H]tubocurarine and [3H]acetylcholine by torpedo postsynaptic membranes: stoichiometry and ligand interactions

1979 • 243 citations

Molecular forms of acetylcholine receptor. Effects of calcium ions and a sulfhydryl reagent on the occurrence of oligomers

1977 • 185 citations

Fast Kinetic Studies on the Interaction of a Fluorescent Agonist with the Membrane‐Bound Acetylcholine Receptor from Torpedo marmorata

1979 • 183 citations

Generation of end-plate potentials

1976 • 176 citations

Binding of Naja nigricollis (3H)alpha-toxin to membrane fragments from Electrophorus and Torpedo electric organs. I. Binding of the tritiated alpha-neurotoxin in the absence of effector.

1974 • 170 citations

Permeability control by cholinergic receptors in Torpedo postsynaptic membranes: agonist dose-response relations measured at second and millisecond times

1980 • 170 citations

Regulation of binding properties of the nicotinic receptor protein by cholinergic ligands in membrane fragments from Torpedo marmorata.

1975 • 169 citations

Kinetics of agonist-mediated transitions in state of the cholinergic receptor.

1977 • 143 citations

Identification of a local anesthetic binding site in nicotinic post-synaptic membranes isolated from Torpedo marmorata electric tissue.

1979 • 120 citations

Ligand-induced conformation changes in Torpedo californica membrane-bound acetylcholine receptor

1978 • 119 citations

Agonist-mediated changes of the acetylcholine receptor in its membrane environment

1978 • 104 citations

Fast Kinetic Studies on the Allosteric Interactions between Acetylcholine Receptor and Local Anesthetic Binding Sites

1979 • 102 citations

Studies on the electrogenic action of acetylcholine with Torpedo marmorata electric organ

1976 • 101 citations

KINETICS OF ALLOSTERIC ENZYMES 9031

1974 • 99 citations

Kinetic evidence for hapten-induced conformational transition in immunoglobin MOPC 460.

1976 • 95 citations

Studies on the electrogenic action of acetylcholine with Torpedo marmorata electric organ

1976 • 92 citations

Disulfide bond cross-linked dimer in acetylcholine receptor from Torpedo californica

1977 • 92 citations

Ligand specificity of state transitions in the cholinergic receptor: behavior of agonists and antagonists.

1979 • 89 citations

Fast Kinetic Studies on the Interaction of Cholinergic Agonists with the Membrane-Bound Acetylcholine Receptor from Torpedo marmorata as Revealed by Quinacrine Fluorescence

1977 • 76 citations

On the voltage-dependent action of tetrodotoxin

1977 • 75 citations

Kinetics of agonist-induced intrinsic fluorescence changes in membrane-bound acetylcholine receptor

1976 • 73 citations

A simple, rapid, and quantitative radiometric assay of acetylcholinesterase

1974 • 61 citations

Binding of perhydrohistrionicotoxin to intact and detergent-solubilized membranes enriched in nicotinic acetylcholine receptor

1979 • 58 citations

Ligand-induced changes in membrane-bound acetylcholine receptor observed by ethidium fluorescence. 2. Stopped-flow studies with agonists and antagonists

1979 • 58 citations

Interaction of local anesthetics with Torpedo californica membrane-bound acetylcholine receptor

1979 • 52 citations

The study of allosteric proteins

1973 • 43 citations

Kinetic analysis of receptor-controlled tracer efflux from sealed membrane fragments

1978 • 35 citations