What roles have anti-interferon antibodies in physiology and pathology?

Naturally occurring antibodies against nine common antigens in human sera. I. Detection, isolation and characterization.

1982 • 665 citations

Resistance to Recombinant Interferon Alfa-2a in Hairy-Cell Leukemia Associated with Neutralizing Anti-Interferon Antibodies

1988 • 251 citations

Interferon-neutralizing antibodies in a patient treated with human fibroblast interferon

1981 • 156 citations

Immunologic Tolerance: Collaboration Between Antigen and Lymphokines

1989 • 135 citations

Defective gamma interferon production in leprosy. Reversal with antigen and interleukin 2.

1983 • 131 citations

Progressive glomerulonephritis in mice treated with interferon preparations at birth

1976 • 115 citations

Influence of anti-mouse interferon serum on the growth and metastasis of tumor cells persistently infected with virus and of human prostatic tumors in athymic nude mice

1981 • 112 citations

Recombinant human interferon (IFN) alpha‐2b in chronic myelogenous leukaemia: dose dependency of response and frequency of neutralizing anti‐interferon antibodies

1989 • 108 citations

ANTIBODIES TO HUMAN LEUCOCYTE INTERFERONS IN CANCER PATIENTS

1983 • 103 citations

The Biology of the Interferon System 1986

1987 • 81 citations

Roles of interferon produced in physiological conditions. A speculative review.

1988 • 77 citations

Unusual apparently constitutive interferons and antagonists in human placental blood.

1985 • 74 citations

Uromodulin. An immunosuppressive 85-kilodalton glycoprotein isolated from human pregnancy urine is a high affinity ligand for recombinant interleukin 1 alpha.

1986 • 73 citations

Recombinant interferon alfa-2a in metastatic renal cell carcinoma: assessment of antitumor activity and anti-interferon antibody formation.

1988 • 71 citations

Regulation of Immune Functions in the Fetus and Newborn1

2015 • 68 citations

Localization of α-interferon in the human feto-placental unit

1988 • 63 citations

The distribution of immunoreactive interferon-alpha in normal human tissues.

1989 • 57 citations

Treatment of anti‐recombinant interferon‐alpha 2 antibody positive CML patients with natural interferon‐alpha

1991 • 56 citations

Assessment of the antigenic response in humans to a recombinant mutant interferon beta

1987 • 47 citations

Recombinant Interferon-γ Inhibits Cell Invasion byEimeria tenella

1989 • 43 citations

The Physiological Interferon Response: IV. Production of Interferon by the Perfused Human Placenta at Term

1985 • 39 citations

Phase I trial of recombinant interleukin-2 and cyclophosphamide: augmentation of cellular immunity and T-cell mitogenic response with long-term administration of rIL-2.

1988 • 36 citations

Interferon in pregnancy.

1989 • 30 citations

Detection and incidence of neutralizing antibodies to interferon-alpha-n1.

1989 • 30 citations

Anti-interferon antibodies to interferon-alpha 2b: results of comparative assays and clinical perspective.

1989 • 28 citations

Sarcolectin: an interferon antagonist extracted from hamster sarcomas and normal muscles. Isolation, characterization, and purification.

1983 • 26 citations

Defective interferon-γ production in ataxia-telangiectasia

1984 • 23 citations

Naturally occurring anti-interferon antibodies in Lou/c rats.

1984 • 21 citations

Production of Two Human 2′,5′-Oligoadenylate Synthetase Enzymes inEscherichia coli

1989 • 20 citations

What is the role of carohydrates in interferons?

1983 • 19 citations

Low incidence of neutralizing antibody formation to interferon-alpha 2b in human recipients.

1989 • 14 citations

Interferon responses in maternal and fetal mice

1985 • 12 citations

Renal deposition of alpha interferon in systemic lupus erythematosus

1983 • 12 citations

Partial Purification of a Placental Interferon with Atypical Characteristics

1983 • 11 citations

Effects of Interferon-γ and Tumor Necrosis Factor-α on Macrophage Enzyme Levels

1989 • 8 citations

Regulation of Immune Functions in the Fetus and Newborn (Part 3 of 4)

1981 • 6 citations

Control of the interferon system: an inhibitor of interferon action.

1981 • 4 citations

Are there pathological defects of interferon secretion in man?

1980 • 3 citations

Deleted Work

1955 • 0 citations