Induction of apoptosis by fenretinide (4HPR) in human ovarian carcinoma cells and its association with retinoic acid receptor expression

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

The Retinoids-Biology, Chemistry and Medicine

1994 • 987 citations

Apoptotic cell death induced by c-myc is inhibited by bcl-2

1992 • 981 citations

The retinoid receptors.

1994 • 665 citations

Suppression of Retinoic Acid Receptor–β in Premalignant Oral Lesions and Its Up-Regulation by Isotretinoin

1995 • 419 citations

Differential expression and ligand regulation of the retinoic acid receptor alpha and beta genes.

1989 • 403 citations

N-(4-Hydroxyphenyl)retinamide, a new retinoid for prevention of breast cancer in the rat.

1979 • 388 citations

Tumor-suppressive effect of the retinoic acid receptor beta in human epidermoid lung cancer cells.

1993 • 282 citations

N-(4-hydroxyphenyl)retinamide induces apoptosis of malignant hemopoietic cell lines including those unresponsive to retinoic acid.

1993 • 249 citations

Five-year administration of fenretinide: pharmacokinetics and effects on plasma retinol concentrations.

1993 • 205 citations

Differential effects of N-(4-hydroxyphenyl)retinamide and retinoic acid on neuroblastoma cells: apoptosis versus differentiation.

1995 • 195 citations

Down-regulation of retinoic acid receptor beta in mammary carcinoma cell lines and its up-regulation in senescing normal mammary epithelial cells.

1994 • 183 citations

In Situ Localization of Apoptosis in the Rat Ovary during Follicular Atresia1

1994 • 171 citations

Retinoids, retinoid-responsive genes, cell differentiation, and cancer.

1992 • 158 citations

Regulation of apoptosis induced by the retinoid N-(4-hydroxyphenyl) retinamide and effect of deregulated bcl-2

1995 • 146 citations

Synthetic retinoid fenretinide is effective against a human ovarian carcinoma xenograft and potentiates cisplatin activity.

1993 • 134 citations

Combination chemotherapy in vitro with adriamycin. Observations of additive, antagonistic, and synergistic effects when used in two-drug combinations on cultured human lymphoma cells.

1976 • 120 citations

MINIREVIEW: Interactions of Retinoids and Transforming Growth Factor-β in Regulation of Cell Differentiation and Proliferation

1991 • 118 citations

Prospects of chemoprevention of human cancers with the synthetic retinoid fenretinide.

1994 • 117 citations

Long-term tolerability of fenretinide (4-HPR) in breast cancer patients

1991 • 116 citations

Internucleosomal dna fragmentation and programmed cell death (apoptosis) in the interdigital tissue of the embryonic chick leg bud

1993 • 113 citations

Occurrence of resistance to retinoic acid in the acute promyelocytic leukemia cell line NB4 is associated with altered expression of the pml/RAR alpha protein

1993 • 111 citations

Neuroblastoma cell apoptosis induced by the synthetic retinoid N‐(4‐hydroxyphenyl)retinamide

1994 • 73 citations

Regulation of apoptosis in normal and malignant ovarian epithelial cells by transforming growth factor beta.

1995 • 72 citations

N‐(4‐hydroxyphenyl) retinamide induces cell cycle specific growth inhibition in PC3 cells

1994 • 63 citations

Modulation of markers associated with tumor aggressiveness in human breast cancer cell lines by N-(4-hydroxyphenyl) retinamide.

1995 • 61 citations

Response of four human ovarian carcinoma cell lines to ALL‐TRANS retinoic acid: Relationship with induction of differentiation and retinoic acid receptor expression

1994 • 49 citations

The human glutathione S-transferase P1-1 gene: modulation of expression by retinoic acid and insulin

1993 • 40 citations

Retinoic acid receptors in retinoid responsive ovarian cancer cell lines detected by polymerase chain reaction following reverse transcription

1993 • 33 citations

Enhancement of cisplatin and etoposide cytotoxicity after all‐trans retinoic‐acid‐induced cellular differentiation of a murine embryonal carcinoma cell line

1993 • 24 citations

Investigation of loss of heterozygosity at specific loci on chromosomes 3p, 6q, 11p, 17p and 17q in ovarian cancer

1993 • 14 citations