Modeling immunotherapy of the tumor - immune interaction

Treatment of 283 Consecutive Patients With Metastatic Melanoma or Renal Cell Cancer Using High-Dose Bolus Interleukin 2

1994 • 1,070 citations

Nonlinear dynamics of immunogenic tumors: Parameter estimation and global bifurcation analysis

1994 • 801 citations

Extravasation of intravascular fluid mediated by the systemic administration of recombinant interleukin 2.

1986 • 534 citations

A Survey of Models for Tumor-Immune System Dynamics

1997 • 344 citations

Nonlinear dynamics of immunogenic tumors: Parameter estimation and global bifurcation analysis

1994 • 315 citations

Cancer Immunotherapy Using Interleukin-2 and Interleukin-2-Activated Lymphocytes

1986 • 307 citations

Treatment of 283 consecutive patients with metastatic melanoma or renal cell cancer using high-dose bolus interleukin 2

1994 • 222 citations

Spontaneous regression of non-Hodgkin's lymphoma: A report of nine cases

1980 • 146 citations

Ultra-late recurrence (15 years or longer) of cutaneous melanoma

1997 • 144 citations

Macrophage T lymphocyte interactions in the anti-tumor immune response: a mathematical model.

1985 • 141 citations

Expression and activity of signaling molecules in T lymphocytes obtained from patients with metastatic melanoma before and after interleukin 2 therapy.

1996 • 111 citations

Predictors of clinical response to interleukin-2--based immunotherapy in melanoma patients: a French multiinstitutional study.

1996 • 100 citations

Bistability in fluctuating environments. Implications in tumor immunology

1979 • 100 citations

Prediction of response to treatment in superficial bladder carcinoma through pattern of interleukin-2 gene expression.

1996 • 98 citations

Spontaneous Cyclic Leukocytosis and Thrombocytosis in Chronic Granulocytic Leukemia

1972 • 94 citations

The Frequency and Morbidity of Local Tumor Recurrence after Definitive Radiotherapy for Stage C Prostate Cancer

1991 • 92 citations

Combination therapy with interferon alfa-2a and interleukin-2 for the treatment of metastatic cancer.

1995 • 89 citations

CYCLIC LEUCOCYTOSIS AS EVIDENCE FOR RETENTION OF NORMAL HOMŒOSTATIC CONTROL IN CHRONIC GRANULOCYTIC LEUKÆMIA

1967 • 86 citations

Recurrence of breast cancer. Obesity, tumor size, and axillary lymph node metastases

1980 • 64 citations

Immune surveillance and neoplasia—1 a minimal mathematical model

1977 • 62 citations

Immunotherapy of metastatic melanoma with interferon-α and interleukin-2: Pattern of progression in responders and patients with stable disease with or without resection of residual lesions

1994 • 32 citations

Phase I study of subcutaneously administered interleukin-2 in combination with interferon alfa-2a in patients with advanced cancer.

1996 • 32 citations

Activation of the Complement System during Immunotherapy of Cancer with Interleukin-2: A Possible Explanation of the Capillary Leak Syndrome

1990 • 31 citations

Modelling and simulation of Rosenberg-type adoptive cellular immunotherapy

1994 • 30 citations

Cyclic Oscillations in Leukocyte Count in Chronic Myeloid Leukemia

1980 • 28 citations

Bistability in fluctuating environments. Implications in tumor immunology

1979 • 27 citations

Effects of vascularization on lymphocyte/tumor cell dynamics: Qualitative features

1996 • 23 citations

Rejection of Mouse Renal Cell Carcinoma Elicited by Local Secretion of Interleukin‐2

1996 • 23 citations

Cancer Immunotherapy Using Interleukin-2 and Interleukin-2-Activated Lymphocytes

1986 • 22 citations

On the Growth of Cellular Tissues Under Constant and Fluctuating Environmental Conditions

1984 • 22 citations

In vitro predictors of clinical response in patients receiving interleukin-2-based immunotherapy

1993 • 21 citations

Influence of Interleukin-2 Regimens on Circulating Populations of Lymphocytes After Adoptive Transfer of Anti-CD3-Stimulated T Cells

1996 • 18 citations

A prospective randomized study of prophylaxis of tumor recurrence following transurethral resection of superficial bladder cancer-intravesical thio-TEPA versus oral UFT

1992 • 15 citations

Immunohistochemical characterisation of immunological changes at the tumour site after chemo-immunotherapy with doxorubicin, interleukin-2 and interferon-gamma.

1996 • 6 citations