Structural interconversion of alternating purine-pyrimidine inverted repeats cloned in supercoiled plasmids

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

Salt-induced co-operative conformational change of a synthetic DNA: Equilibrium and kinetic studies with poly(dG-dC)

1972 • 1,213 citations

THE CHEMISTRY AND BIOLOGY OF LEFT-HANDED Z-DNA

1984 • 1,149 citations

The Writhing Number of a Space Curve

1971 • 754 citations

Cruciform structures in supercoiled DNA

1981 • 545 citations

Left-handed Z-DNA is induced by supercoiling in physiological ionic conditions

1982 • 439 citations

Facile transition of poly[d(TG)·d(CA)] into a left-handed helix in physiological conditions

1983 • 335 citations

Map of distamycin, netropsin, and actinomycin binding sites on heterogeneous DNA: DNA cleavage-inhibition patterns with methidiumpropyl-EDTA.Fe(II).

1982 • 332 citations

Flipping of cloned d(pCpG)n.d(pCpG)n DNA sequences from right- to left-handed helical structure by salt, Co(III), or negative supercoiling.

1982 • 321 citations

Chemical probes of DNA conformation: detection of Z-DNA at nucleotide resolution

1985 • 286 citations

Left-handed DNA in restriction fragments and a recombinant plasmid

1981 • 277 citations

Facile cruciform formation by an (A-T)34 sequence from a Xenopus globin gene

1985 • 186 citations

Poly(ADP-ribosylation) of DNA topoisomerase I from calf thymus.

1984 • 178 citations

Diethyl pyrocarbonate: a chemical probe for secondary structure in negatively supercoiled DNA.

1985 • 169 citations

Proton NMR studies on the interaction between distamycin A and a symmetrical DNA dodecamer

1986 • 151 citations

The facile generation of covalently closed, circular DNAs with defined negative superhelical densities

1982 • 139 citations

Conditions which cause the right-handed to left-handed DNA conformational transitions. Evidence for several types of left-handed DNA structures in solution.

1982 • 138 citations

Transition of a cloned d(AT)n-d(AT)n tract to a cruciformin vivo

1985 • 130 citations

Determination of Base Sequence in Nucleic Acids with the Electron Microscope. V. The Thymine-Specific Reactions of Osmium Tetroxide with Deoxyribonucleic Acid and Its Components^*

1966 • 127 citations

Intervening sequences in human fetal globin genes adopt left-handed Z helices.

1984 • 121 citations

The supercoil-stabilised cruciform of ColE1 is hyper-reactive to osmium tetroxide.

1984 • 120 citations

S1 nuclease recognizes DNA conformational junctions between left-handed helical (dT-dG n. dC-dA)n and contiguous right-handed sequences.

1984 • 119 citations

Conformational flexibility of junctions between contiguous B- and Z-DNAs in supercoiled plasmids.

1983 • 113 citations

Selective degradation of thymidine and thymine deoxynucleotides

1966 • 106 citations

Highly selective chemical modification of cruciform loops by diethyl pyrocarbonate

1986 • 100 citations

Consecutive A X T pairs can adopt a left-handed DNA structure.

1986 • 99 citations

Spectroscopic studies on acetylaminofluorene-modified (dT-dG)n . (dC-dA)n suggest a left-handed conformation.

1982 • 89 citations

Conformational transitions of poly(dA-dC).poly(dG-dT) induced by high salt or in ethanolic solution

1982 • 89 citations

Relationship between superhelical density and cruciform formation in plasmid pVH51.

1982 • 88 citations

Effects of 5 cytosine methylation on the B-Z transition in DNA restriction fragments and recombinant plasmids

1983 • 81 citations

An assessment of the Z-DNA forming potential of alternating dA-dT stretches in supercoiled plasmids

1986 • 80 citations

Diethyl pyrocarbonate: a chemical probe for DNA cruciforms

1986 • 76 citations

Site-specific OsO4 modification of the B-Z junctions formed at the (dA-dC)32 region in supercoiled DNA.

1986 • 72 citations

Hhalmethylase and restriction endonuclease as probes for B to Z DNA conformational changes in d(GCGC) sequences

1984 • 71 citations

A Structural Transition in d(AT)_n·d(AT)_nInserts within Superhelical DNA

1985 • 69 citations

The structure of cruciforms in supercoiled DNA: probing the single-stranded character of nucleotide bases with bisulphite.

1986 • 63 citations

Osmium-labeled polynucleotides. The reaction of osmium tetroxide with deoxyribonucleic acid and synthetic polynucleotides in the presence of tertiary nitrogen donor ligands

1977 • 60 citations

Recognition of the Structural Distortions at the Junctions Between B and Z Segments in Negatively Supercoiled DNA by Osmium Tetroxide

1985 • 58 citations

A two-state conformational equilibrium for alternating (A-T)n sequences in negatively supercoiled DNA

1987 • 52 citations

The influence of the purine 2-amino group on DNA conformation and stability. Synthesis and conformational analysis of d[T(2-aminoA)]₃

1982 • 51 citations

Left-handed DNA Helices, Supercoiling, and the B-Z Junction

1983 • 48 citations

B-Z DNA junctions contain few, if any, nonpaired bases at physiological superhelical densities.

1985 • 47 citations

Temperatare dependence of the gel electrophoretic mobility of superhelical DNA

1985 • 47 citations

Z Form of Poly d(A-T) · Poly d(A-T) in Solution Studied by CD and UV Spectroscopies

1987 • 46 citations

Thermodynamic parameters are sequence-dependent for the supercoil-induced B to Z transition in recombinant plasmids.

1986 • 40 citations

Stress-induced cruciform formation in a cloned d(CATG)10 sequence.

1986 • 36 citations

B- to Z-DNA transition probed by oligonucleotides containing methylphosphonates.

1986 • 31 citations

DNA: Sequence, Structure and Supercoiling

1984 • 28 citations