Mivazerol, a novel compound with high specificity for α2 adrenergic receptors: Binding studies on different human and rat membrane preparations

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1973 • 12,522 citations

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

1980 • 8,534 citations

Alpha-2A and alpha-2B adrenergic receptor subtypes: antagonist binding in tissues and cell lines containing only one subtype.

1988 • 307 citations

Characterization of α1-and α2-Adrenergic Receptors

1983 • 230 citations

Neural mechanisms in life-threatening arrhythmias

1980 • 164 citations

Human platelet α2-adrenergic receptors: Labeling with 3H-yohimbine, a selective antagonist ligand

1981 • 142 citations

Delineation of rat kidney α2A- and α2B-adrenoeeptors with [3H]RX821002 radiollgand binding: computer modelling reveals that guanfacine is an α2A-selective compound

1991 • 137 citations

Autoradiographic localization of D1 and D2 dopamine receptors in the human brain

1988 • 124 citations

Novel α2-adrenoceptor antagonists show selectivity for α2A- and α2B-adrenoceptor subtypes

1989 • 109 citations

Alpha-2 adrenergic receptor subtypes indicated by [3H]yohimbine binding in human brain

1986 • 88 citations

The deleterious effects of myocardial catecholamines on cellular electrophsiology and arrhythmias during ischaemia and reperfusion

1984 • 86 citations

D1 dopamine receptors in human putamen, frontal cortex and calf retina: differences in guanine nucleotide regulation of agonist binding and adenylate cyclase stimulation

1988 • 64 citations

High affinity binding of 3H rauwolscine and 3H RX781094 to α2 adrenergic receptors and non-stereo selective sites in human and rabbit brain cortex membranes

1989 • 62 citations

Alpha2-adrenergic agonists in cardiovascular anesthesia

1992 • 58 citations

Regional Distribution of α_2A‐and α_2B‐Adrenoceptor Subtypes in Postmortem Human Brain

1992 • 55 citations

Clonidine Prevents the Sympathetic Initiation and Aggravation of Poststenotic Myocardial Ischemia

1985 • 49 citations

Peripheral presynaptic and central effects of clonidine, yohimbine and rauwolscine on the sympathetic nervous system in rabbits

1989 • 44 citations

Heterogeneos 3H-rauwolscine binding sites in rat cortex: Two alpha2-adrenoceptor subtypes or an additional non-adrenergic interaction?

1988 • 42 citations

[3H]Rauwolscine labels α2-adrenoceptors and 5-HT1A receptors in human cerebral cortex

1989 • 39 citations

Identification of α2 adrenergic receptors in human frontal cortex membranes by binding of [3H]RX 821002, the 2-methoxy analog of [3H]idazoxan

1990 • 36 citations

Regional distribution of the dopamine D2 receptors in the mesotelencephalic dopamine neuron system of human brain

1985 • 35 citations

Adrenergic Mechanisms in Myocardial Infarction

1988 • 34 citations

Human M1-, M2- and M3-muscarinic cholinergic receptors: Binding characteristics of agonists and antagonists

1990 • 32 citations

Shallow agonist competition binding curves for beta-adrenergic receptors: the role of tight agonist binding.

1987 • 25 citations

Antianginal Effects of Clonidine

1986 • 25 citations

Tight agonist binding may prevent the correct interpretation of agonist competition binding curves for alpha 2-adrenergic receptors.

1987 • 23 citations

[3H]SCH 23390 labels a novel 5-hydroxytryptamine binding site in human blood platelet membranes

1989 • 22 citations

Identification of human platelet a₂‐adrenoceptors with a new antagonist [³H]‐RX821002, a 2‐methoxy derivative of idazoxan

1990 • 22 citations

Identification and characterization of α1-adrenergic receptors in human myometrium by [3H]prazosin binding

1983 • 20 citations

Intravenous clonidine in acute myocardial infarction in men

1984 • 19 citations

Clonidine effect in chronic angina pectoris. Double-blind, crossover trial on 60 patients.

1979 • 18 citations

Intravenous clonidine treatment in acute myocardial infarction (with comparison to a nitroglycerin-treated and control group).

1986 • 16 citations

Intravenous Clonidine Treatment in Acute Myocardial Infarction (with Comparison to a Nitroglycerin-Treated and Control Group)

1986 • 11 citations

Agonist/N-ethylmaleimide mediated inactivation of β-adrenergic receptors

1985 • 9 citations

EFFECT OF CLONIDINE ON ADRENAL MEDULLA CATECHOLAMINE LEVELS IN RATS

1987 • 9 citations

Mivazerol, a new α2-adrenergic agonist with anti-ischaemic effects in animal models of myocardial ischaemia

1994 • 6 citations

Mivazerol, an α2-adrenoceptor agonist, improves exercise induced ischaemia in patients with angina pectoris

1994 • 4 citations

Mivazerol, a new ?2-adrenoceptor agonist, increases the ventricular fibrillation threshold in anaesthetised dogs

1991 • 3 citations

Levodopa up-regulates platelet α2-adrenoceptors

1990 • 2 citations

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