Production of neutralizing granulocyte-macrophage colony-stimulating factor (GM-CSF) antibodies in carcinoma patients following GM-CSF combination therapy

Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity.

1993 • 2,828 citations

Viral Hepatitis and Liver Disease

1985 • 1,886 citations

Human GM-CSF: Molecular Cloning of the Complementary DNA and Purification of the Natural and Recombinant Proteins

1985 • 1,253 citations

Establishment and characterization of a unique human cell line that proliferates dependently on GM‐CSF, IL‐3, or erythropoietin

1989 • 833 citations

Human Recombinant Granulocyte-Macrophage Colony-Stimulating Factor: A Multilineage Hematopoietin

1985 • 374 citations

Cloning, sequence, and expression of a human granulocyte/macrophage colony-stimulating factor.

1985 • 314 citations

Granulocyte-macrophage colony-stimulating factor augments the primary antibody response by enhancing the function of antigen-presenting cells.

1987 • 299 citations

Human recombinant granulocyte-macrophage colony-stimulating factor increases cell-to-cell adhesion and surface expression of adhesion-promoting surface glycoproteins on mature granulocytes.

1986 • 284 citations

Resistance to Recombinant Interferon Alfa-2a in Hairy-Cell Leukemia Associated with Neutralizing Anti-Interferon Antibodies

1988 • 251 citations

Activation of antibody-dependent cell-mediated cytotoxicity of human neutrophils and eosinophils by separate colony-stimulating factors.

1983 • 248 citations

Neutralizing Antibodies to Interferon- : Relative Frequency in Patients Treated with Different Interferon Preparations

1991 • 214 citations

Purification and properties of bacterially synthesized human granulocyte-macrophage colony stimulating factor

1987 • 211 citations

Development of antibodies to unprotected glycosylation sites on recombinant human GM-CSF

1990 • 207 citations

Subcutaneous granulocyte-macrophage colony-stimulating factor in patients with myelodysplastic syndrome: toxicity, pharmacokinetics, and hematological effects.

1989 • 179 citations

Recombinant human interferon (IFN) alpha‐2b in chronic myelogenous leukaemia: dose dependency of response and frequency of neutralizing anti‐interferon antibodies

1989 • 108 citations

Induction of anti-recombinant human granulocyte-macrophage colony- stimulating factor (Escherichia coli-derived) antibodies and clinical effects in nonimmunocompromised patients

1994 • 102 citations

Effect of monoclonal antibody 17‐1A and gm‐CSF in patients with advanced colorectal carcinoma—long‐lasting, complete remissions can be induced

1993 • 101 citations

Neutralizing antibodies to recombinant alpha-interferon and response to therapy in chronic hepatitis C virus infection

1993 • 84 citations

Clinical properties of yeast-derived versus Escherichia coli-derived granulocyte-macrophage colony-stimulating factor.

1993 • 81 citations

Regulation of human monocyte adherence by granulocyte-macrophage colony-stimulating factor.

1989 • 71 citations

Granulocyte-monocyte-colony-stimulating factor augments the cytotoxic capacity of lymphocytes and monocytes in antibody-dependent cellular cytotoxicity

1989 • 70 citations

Effective natural interferon-alpha therapy in recombinant interferon- alpha-resistant patients with hairy cell leukemia

1991 • 63 citations

Characterization of anti-interferon-α antibodies appearing during recombinant interferon-α2a treatment

1992 • 50 citations

Development of immunoassays for human interleukin 3 and interleukin 4, some of which discriminate between different recombinant DNA-derived molecules

1991 • 21 citations

Quantitative biological assays for individual cytokines

1995 • 15 citations

The use of haemopoietic growth factors in the treatment of myelodysplastic syndromes.

1990 • 14 citations

Purification and properties of bacterially synthesized human granulocyte-macrophage colony stimulating factor

1987 • 13 citations