Why is epidermal growth factor present in the gut lumen?

Targeted Disruption of Mouse EGF receptor: Effect of Genetic Background on Mutant Phenotype

1995 • 1,457 citations

Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor

1995 • 1,035 citations

Strain-Dependent Epithelial Defects in Mice Lacking the EGF Receptor

1995 • 1,016 citations

TGFα deficiency results in hair follicle and eye abnormalities in targeted and waved-1 mice

1993 • 659 citations

Induction of a novel epidermal growth factor-secreting cell lineage by mucosal ulceration in human gastrointestinal stem cells

1990 • 465 citations

Epidermal growth factor-related peptides and their relevance to gastrointestinal pathophysiology

1995 • 329 citations

Trefoil peptide gene expression in gastrointestinal epithelial cells in inflammatory bowel disease

1993 • 256 citations

Immunohistochemical localisation of urogastrone to human duodenal and submandibular glands.

1978 • 198 citations

Intravenous but not intragastric urogastrone-EGF is trophic to the intestine of parenterally fed rats.

1987 • 146 citations

Effect of sialoadenectomy and synthetic human urogastrone on healing of chronic gastric ulcers in rats.

1986 • 137 citations

Effect of luminal growth factor preservation on intestinal growth

1993 • 117 citations

Epidermal growth factor is digested to smaller, less active forms in acidic gastric juice

1995 • 114 citations

Combined Intestinal Trefoil Factor and Epidermal Growth Factor is Prophylactic against Indomethacin-Induced Gastric Damage in the Rat

1995 • 112 citations

Peptides and gastrointestinal mucosal integrity.

1995 • 95 citations

Physiological concentrations of human epidermal growth factor in biological fluids: use of a sensitive enzyme immunoassay

1986 • 82 citations

Developmental regulation of epidermal growth factor receptor kinase in rat intestine

1994 • 73 citations

Characterization and autoradiographic localization of the epidermal growth factor receptor in the jejunum of neonatal and weaned pigs

1992 • 69 citations

Effect of sialoadenectomy and salivary gland extracts on gastrointestinal mucosal growth and gastrin levels in the rat.

1984 • 54 citations

Hypersecretion of submandibular saliva in male mice: Trophic response in small intestine

1983 • 48 citations

Luminal Epidermal Growth Factor is Trophic to the Small Intestine of Parenterally Fed Rats

1995 • 38 citations

Gastric Ulcer is Accompanied by a Decrease of Epidermal Growth Factor in Gastric Juice and Saliva

1989 • 11 citations

The EGF-receptor (EGF-R) is present on the basolateral, but not apical, surface of enterocytes in the human gastrointestinal tract

1995 • 4 citations