Basic FGF and TGF-β differentially modulate integrin expression of human microvascular endothelial cells

Angiogenic Factors

1987 • 3,702 citations

Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix.

1986 • 2,499 citations

Integrins and other cell adhesion molecules

1990 • 1,990 citations

Integrins.

1991 • 1,369 citations

Capillary endothelial cells express basic fibroblast growth factor, a mitogen that promotes their own growth

1987 • 764 citations

Regulation of Cell Adhesion Receptors by Transforming Growth Factor-β

1989 • 672 citations

In vitro angiogenesis on the human amniotic membrane: requirement for basic fibroblast growth factor-induced proteinases.

1989 • 462 citations

Endothelial cells use alpha 2 beta 1 integrin as a laminin receptor.

1989 • 363 citations

The primary structure of the VLA-2/collagen receptor alpha 2 subunit (platelet GPIa): homology to other integrins and the presence of a possible collagen-binding domain.

1989 • 343 citations

Fibronectin Matrix Deposition and Fibronectin Receptor Expression in Healing and Normal Skin

1990 • 314 citations

Transforming growth factor-beta inhibits endothelial cell proliferation

1986 • 313 citations

Inhibition of endothelial cell proliferation by type β-transforming growth factor: Interactions with acidic and basic fibroblast growth factors

1986 • 312 citations

The role of integrins in the maintenance of endothelial monolayer integrity.

1991 • 290 citations

The vitronectin receptor alpha v beta 3 binds fibronectin and acts in concert with alpha 5 beta 1 in promoting cellular attachment and spreading on fibronectin.

1990 • 282 citations

Regulation of Cell Adhesion Receptors by Transforming Growth Factor-β

1989 • 272 citations

The alpha 1-alpha 6 subunits of integrins are characteristically expressed in distinct segments of developing and adult human nephron.

1990 • 261 citations

Blood Vessel Fibronectin Increases in Conjunction with Endothelial Cell Proliferation and Capillary Ingrowth During Wound Healing

1982 • 211 citations

Transforming growth factor-β switches the pattern of integrins expressed in MG-63 human osteosarcoma cells and causes a selective loss of cell adhesion to laminin

1989 • 199 citations

Fibronectin is produced by blood vessels in response to injury.

1982 • 155 citations

Human microvascular endothelial cells use beta 1 and beta 3 integrin receptor complexes to attach to laminin.

1990 • 155 citations

Tumor necrosis factor alpha and interferon gamma modulate the expression of the vitronectin receptor (integrin beta 3) in human endothelial cells.

1991 • 139 citations

Endothelial Cells Synthesize Basic Fibroblast Growth Factor and Transforming Growth Factor Beta

1988 • 119 citations

Spatiotemporal segregation of endothelial cell integrin and nonintegrin extracellular matrix-binding proteins during adhesion events.

1990 • 104 citations

Endothelial cell behavior after denudation injury is modulated by transforming growth factor-beta1 and fibronectin.

1989 • 101 citations

Human microvascular endothelial cells express integrin‐related complexes that mediate adhesion to the extracellular matrix

1989 • 93 citations

The integrin complex αvβ3 participates in the adhesion of microvascular endothelial cells to fibronectin

1991 • 55 citations

Individual embryonic fibroblasts express multiple beta chains in association with the alpha v integrin subunit. Loss of beta 3 expression with cell confluence.

1991 • 53 citations

Cell Adhesion Mechanisms and Their Potential Impact on Wound Healing and Tumor Control

1990 • 24 citations