Pygopus Residues Required for its Binding to Legless Are Critical for Transcription and Development

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

1993 • 9,476 citations

Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC

1997 • 3,847 citations

Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC ^−/− Colon Carcinoma

1997 • 3,234 citations

Wnt signaling and cancer

2000 • 3,215 citations

Wnt signaling: a common theme in animal development

1997 • 2,579 citations

The β-Catenin/TCF-4 Complex Imposes a Crypt Progenitor Phenotype on Colorectal Cancer Cells

2002 • 1,984 citations

Linking Colorectal Cancer to Wnt Signaling

2000 • 1,507 citations

Armadillo Coactivates Transcription Driven by the Product of the Drosophila Segment Polarity Gene dTCF

1997 • 1,201 citations

Structure of a c-Cbl–UbcH7 Complex

2000 • 824 citations

The oncogenic activation of β-catenin

1999 • 655 citations

The p300/CBP acetyltransferases function as transcriptional coactivators of beta-catenin in vertebrates

2000 • 596 citations

Wnt/Wingless Signaling Requires BCL9/Legless-Mediated Recruitment of Pygopus to the Nuclear β-Catenin-TCF Complex

2002 • 548 citations

The Transcriptional Coactivator Cbp Interacts with β-Catenin to Activate Gene Expression

2000 • 468 citations

The PHD Finger of the Chromatin-Associated Protein ING2 Functions as a Nuclear Phosphoinositide Receptor

2003 • 467 citations

The chromatin remodelling factor Brg-1 interacts with beta-catenin to promote target gene activation

2001 • 440 citations

Modulation of Transcriptional Regulation by LEF-1 in Response to Wnt-1 Signaling and Association with β-Catenin

1998 • 366 citations

The APC tumour suppressor has a nuclear export function

2000 • 348 citations

A new nuclear component of the Wnt signalling pathway

2002 • 287 citations

Pygopus, a nuclear PHD-finger protein required for Wingless signaling inDrosophila

2002 • 236 citations

Solution structure of the PHD domain from the KAP-1 corepressor: structural determinants for PHD, RING and LIM zinc-binding domains

2001 • 197 citations

pygopusencodes a nuclear protein essential for Wingless/Wnt signaling

2002 • 179 citations

Structure of the PHD Zinc Finger from Human Williams-Beuren Syndrome Transcription Factor

2000 • 155 citations

Sla1p serves as the targeting signal recognition factor for NPFX(1,2)D-mediated endocytosis

2002 • 121 citations

The sequence NPFXD defines a new class of endocytosis signal in Saccharomyces cerevisiae.

1996 • 109 citations

β-catenin: molecular plasticity and drug design

2001 • 80 citations

Efficient Inhibition of Escherichia Coli RNA Polymerase by the Bacteriophage T4 AsiA Protein Requires that AsiA Binds First to Free σ70

2000 • 67 citations