Mechanism of tubulin assembly: role of rings in the nucleation process and of associated proteins in the stabilization of microtubules

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

A protein factor essential for microtubule assembly.

1975 • 2,863 citations

Microtubule Assembly in the Absence of Added Nucleotides

1973 • 2,055 citations

Turbidimetric studies of the in vitro assembly and disassembly of porcine neurotubules

1974 • 814 citations

Opposite end assembly and disassembly of microtubules at steady state in vitro

1978 • 567 citations

In vitro reconstitution of calf brain microtubules: effects of solution variables

1977 • 333 citations

Kinetics of Exchange Reactions

1938 • 278 citations

Kinetic analysis of microtubule self-assembly in vitro

1977 • 260 citations

Microtubule Assembly and Nucleation

1978 • 253 citations

Role of tubulin-associated proteins in microtubule nucleation and elongation

1977 • 225 citations

Neurofilament proteins of rat peripheral nerve and spinal cord.

1978 • 219 citations

Separation and characterization of microtubule proteins from calf brain

1977 • 203 citations

Microtubules from Mammalian Brain: Some Properties of Their Depolymerization Products and a Proposed Mechanism of Assembly and Disassembly

1974 • 200 citations

Identity and polymerization-stimulatory activity of the nontubulin proteins associated with microtubules

1977 • 184 citations

Kinetic analysis of cooperativity in tubulin polymerization in the presence of guanosine di- or triphosphate nucleotides

1978 • 177 citations

Guanosinetriphosphatase activity of tubulin associated with microtubule assembly.

1977 • 174 citations

Arrangement of high molecular weight associated proteins on purified mammalian brain microtubules.

1977 • 155 citations

A dynein‐like protein associated with neurotubules

1974 • 154 citations

Microtubule assembly: Some possible regulatory mechanisms

1974 • 148 citations

Assembly of microtubules from preformed, ring‐shaped protofilaments and 6‐s tubulin

1974 • 136 citations

In vitro assembly of pure tubulin into microtubules in the absence of microtubule-associated proteins and glycerol.

1977 • 124 citations

Quantitative electron microscopy of microtubule assembly in vitro

1975 • 123 citations

The mechanism of microtubule assembly in vitro

1974 • 109 citations

The non-tubulin component of microtubule protein oligomers. Effect on self-association and hydrodynamic properties.

1978 • 106 citations

Study of the 10-nm-filament fraction isolated during the standard microtubule preparation

1980 • 93 citations

X-ray kinetic studies of microtubule assembly using synchrotron radiation

1980 • 93 citations

The polypeptides of isolated brain 10nm filaments and their association with polymerized tubulin

1979 • 60 citations

Rate of isotope exchange in enzyme-catalyzed reactions

1969 • 59 citations

A kinetic analysis of the assembly of microtubules in vitro

1977 • 57 citations

Role of co-operative interactions, microtubule-associated proteins and guanosine triphosphate in microtubule assembly: a model.

1980 • 55 citations

Identification of the major 68,000-dalton protein of microtubule preparations as a 10-nm filament protein and its effects on microtubule assembly in vitro

1979 • 53 citations

Incorporation of radioactive tubulin into microtubules at steady state. Experimental and theoretical analyses of diffusional and directional flux.

1980 • 51 citations

Tubulin‐Associated Nucleoside Diphosphokinase

1979 • 48 citations

The role of ring aggregates and other structures in the assembly of microtubules

1974 • 45 citations

Preferential blockade of the tubulin transport by colchicine

1980 • 34 citations

Nucleotide release from tubulin and nucleoside-5'-diphosphate kinase action in microtubule assembly.

1979 • 28 citations

Radioiodination of brain tubulin with Bolton-Hunter reagent

1980 • 17 citations

Purification of a microtubule‐associated protein based on its preferential association with tubulin during microtubule initiation

1979 • 16 citations

Rings are not microtubule assembly intermediates: An analysis of the lag phase in GTP-dependent self-assembly of bovine brain tubulin

1980 • 15 citations

A pressure relaxation study of tubulin oligomer formation

1980 • 11 citations

Préparation de microtubules hautement purifiés et mise en évidence d'un arrangement nouveau des molécules de tubuline à basse température

1977 • 2 citations