In Vitro Activity of Fluoroquinolones against Gram-Positive Bacteria

Quinolone antimicrobial agents

1989 • 421 citations

In vitro and in vivo antibacterial activities of levofloxacin (l-ofloxacin), an optically active ofloxacin

1992 • 217 citations

In vitro activity of CP-99,219, a new fluoroquinolone, against clinical isolates of gram-positive bacteria

1993 • 134 citations

Antimicrobial activity of DU-6859, a new potent fluoroquinolone, against clinical isolates

1992 • 126 citations

In vitro antimicrobial activity of CP-99,219, a novel azabicyclo-naphthyridone

1993 • 125 citations

In vitro and in vivo antibacterial activities of AM-1155, a new 6-fluoro-8-methoxy quinolone

1992 • 117 citations

In vitro antibacterial activity of AM-1155, a novel 6-fluoro-8-methoxy quinolone

1994 • 94 citations

Susceptibilities of penicillin-susceptible and -resistant strains of Streptococcus pneumoniae to RP 59500, vancomycin, erythromycin, PD 131628, sparfloxacin, temafloxacin, win 57273, ofloxacin, and ciprofloxacin

1992 • 90 citations

Comparative in-vitro activities of the new quinolone, Bay y 3118, and ciprofloxacin, sparfioxacin, tosufloxacin, CI-960 and CI-990

1993 • 58 citations

In vitro and in vivo antibacterial activities of T-3761, a new quinolone derivative

1993 • 55 citations

The in-vitro activity of OPC-17116, a new 5-methyl substituted quinolone

1993 • 53 citations

In vitro activity of OPC-17116

1992 • 49 citations

Antibacterial activity of NM394, the active form of prodrug NM441, a new quinolone

1993 • 45 citations

In vitro antibacterial activity of Q-35, a new fluoroquinolone

1992 • 41 citations

Comparative in vitro activities of a new quinolone, OPC-17116, possessing potent activity against gram-positive bacteria

1992 • 38 citations

Susceptibilities of bacterial isolates from patients with cancer to levofloxacin and other quinolones

1994 • 38 citations

In vitro activity of DU-6859a, a new fluorocyclopropyl quinolone

1993 • 38 citations

In vitro activity of T-3761, a new fluoroquinolone

1992 • 37 citations

The in-vitro activity of a new highly active quinolone, DU-6859a

1993 • 28 citations

Comparative in vitro activity of DU-6859a, a new fluoroquinolone agent, against gram-positive cocci

1994 • 26 citations

In-vitro activity of OPC-17116 against more than 6000 consecutive clinical isolates: a multicentre international study

1994 • 24 citations

In vitro activities of BAY Y3118, ciprofloxacin, ofloxacin, and fleroxacin against gram-positive and gram-negative pathogens from respiratory tract and soft tissue infections

1993 • 23 citations

Comparative in vitro activity of PD 127391, a new fluoroquinolone agent, against susceptible and resistant clinical isolates of gram-positive cocci

1992 • 22 citations

In vitro and in vivo evaluations of A-80556, a new fluoroquinolone

1994 • 22 citations

The in-vitro susceptibilities of 326 Streptococcus pneumoniae isolates to nine antimicrobial agents including penicillin and newer quinolones

1994 • 20 citations

Antimicrobial activity of DV-7751a, a new fluoroquinolone

1993 • 19 citations

Comparative in vitro activities of new quinolones against coryneform bacteria

1994 • 19 citations

In vitro activity of Bay y 3118, a new quinolone

1993 • 19 citations

In vitro activity of sparfloxacin (AT-4140, CI-978, PD 131501), a new quinolone antimicrobial agent

1990 • 17 citations

In vitro activities of ramoplanin, selected glycopeptides, fluoroquinolones, and other antibiotics against clinical bloodstream isolates of gram-positive cocci

1993 • 16 citations

In vitro and in vivo antibacterial activities of E-4868, a new fluoroquinolone with a 7-azetidin ring substituent

1993 • 16 citations

Comparative in vitro activity of WIN 57273, a new fluoroquinolone antimicrobial agent

1990 • 16 citations

In vitro antistaphylococcal activities of two investigative fluoroquinolones, CI-960 and WIN 57273, compared with those of ciprofloxacin, mupirocin (pseudomonic acid), and peptide-class antimicrobial agents

1992 • 15 citations

In-vitro activity of PD 131628, a new quinolone antimicrobial agent

1992 • 13 citations

In vitro antibacterial activities of PD 138312 and PD 140248, new fluoronaphthyridines with outstanding gram-positive potency

1993 • 11 citations

Bactericidal activities of DU-6859a and clinafloxacin (CI-960) against staphylococci

1994 • 9 citations

Bactericidal activity of the fluoroquinolone WIN 57273 against high-level gentamicin-resistant Enterococcus faecalis

1993 • 8 citations